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KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009].. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Antibodies (49) and Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Proteins (5) and many more products for this protein.
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NKp80 is a marker of natural killer (NK) cell maturity in secondary lymphoid tissues and supports NK cell development through a stage 4a intermediate with ILC3-associated features.
In the second trimester, functional markers of Decidual natural killer activation, i.e., angiogenic factor (show VEGFA ELISA Kits) production (e.g., vascular endothelial growth factor, interleukin-8 (show IL8 ELISA Kits), interferon-gamma (show IFNG ELISA Kits)), remained stable despite an increase in NKp80 or NKG2D (show KLRK1 ELISA Kits) surface expression.
IL-15 (show IL15 ELISA Kits)+IL-12 (show IL12A ELISA Kits) has an immunomodulatory effect on NK cell subsets from HIV-infected individuals viz down-regulation of iNKRs, elevation of activatory receptors NKp46 (show NCR1 ELISA Kits) and NKG2D (show KLRK1 ELISA Kits), and induction of coreceptor NKp80.
our data report a previously unrecognized regulatory circuit enabling autonomous control of human NK cell responses via the NKp80-AICL (show CLEC2B ELISA Kits) axis.
Two non-consensus amino acids of NKp80, in particular arginine 6, critically impair both hemi-immunoreceptor tyrosine-based activation motif phosphorylation and Syk (show SYK ELISA Kits) recruitment.
Activating receptor NKp80 induces cytotoxicity by using an atypical hemi-ITAM amino acid seqeuence and the Syk (show SYK ELISA Kits)-kinase pathway.
NKp80 is expressed on a highly responsive subset of effector memory CD8 (show CD8A ELISA Kits) T cells with an inflammatory NK-like phenotype and promotes T-cell responses toward AICL (show CLEC2B ELISA Kits)-expressing cells.
phenotypic, molecular, and functional characterization for triggering molecules (NKp46 (show NCR1 ELISA Kits), NKp30 (show NCR3 ELISA Kits) NKp80, and NKG2D (show KLRK1 ELISA Kits); in this AIDS-resistant species, relevant differences to human NK cells involve NKp80 and particularly NKp30 (show NCR3 ELISA Kits)
KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009
C-type lectin domain family 5 member C
, activating coreceptor NKp80
, killer cell lectin-like receptor F1
, killer cell lectin-like receptor subfamily F member 1
, lectin-like receptor F1
, killer cell lectin-like receptor subfamily F, member 1
, NKp80 receptor
, Activating coreceptor NKp80
, Lectin-like receptor F1
, NKp80 NK receptor