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anti-LMBR1 Domain Containing 1 (LMBRD1) Antibodies

LMBRD1 encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. Additionally we are shipping LMBR1 Domain Containing 1 Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LMBRD1 55788 Q9NUN5
LMBRD1 68421 Q8K0B2
LMBRD1 246046 Q6AZ61
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Top anti-LMBR1 Domain Containing 1 Antibodies at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg 4 to 8 Days
$539.00
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Colon, Myenteric Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Colon, Myenteric Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 6 to 8 Days
$511.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg 12 to 14 Days
$667.92
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   100 μg 15 to 19 Days
$513.04
Details
Human Rabbit Un-conjugated ELISA, FM, IHC, WB   100 μg 1 to 2 Days
$405.90
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of LMBRD1 in human brain tissue lysate with LMBRD1 polyclonal antibody at 1 ug/mL. Immunohistochemical staining of human brain cells with LMBRD1 polyclonal antibody at 2.5 ug/mL. 100 μg 11 to 12 Days
$460.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using LMBRD1 antibody. 100 μL 6 to 11 Days
$390.55
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical staining of human hippocampus with LMBRD1 polyclonal antibody shows strong cytoplasmic positivity in neuronal cells. Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with LMBRD1 polyclonal antibody . 100 μL 11 to 12 Days
$577.33
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg 2 to 3 Days
$370.00
Details

More Antibodies against LMBR1 Domain Containing 1 Interaction Partners

Human LMBR1 Domain Containing 1 (LMBRD1) interaction partners

  1. endogenous ABCD4 was localized to both lysosomes and the ER, and its lysosomal localization was disturbed by knockout of LMBRD1

  2. Data suggest that ABCD4 lysosomal targeting depends on co-expression of and interaction with LMBRD1; mutations in LMBRD1 and ABCD4 that result in cobalamin metabolism disorders cblF and cblJ (or mutations in ATPase domain) disrupt interactions between LMBRD1 and ABCD4. (LMBRD1 = nuclear export signal-interacting protein; ABCD4 = ATP-binding cassette, sub-family D (ALD), member 4)

  3. Results propose a model whereby membrane-bound LMBD1 and ABCD4 facilitate the vectorial delivery of lysosomal vitamin B12 to cytoplasmic MMACHC.

  4. LMBD1 plays an imperative role in mediating and regulating the endocytosis of the IR.

  5. These data indicate that by forming complexes with lamin A/C and nucleoporins, NESI facilitates the CRM1-independent nuclear export of large hepatitis delta antigen.

  6. novel mutations in LMBRD1 in three patients

  7. LMBRD1: the gene for the cblF defect of vitamin B metabolism.

  8. a LMBRD1 mutation causes the cblF defect of vitamin B(12) metabolism in a Turkish patient [case report]

  9. LMBRD1 is the gene underlying the cblF defect of cobalamin metabolism and suggests that LMBD1 is a lysosomal membrane exporter for cobalamin.

Mouse (Murine) LMBR1 Domain Containing 1 (LMBRD1) interaction partners

  1. By studying the heterozygous knockout of Lmbrd1 (Lmbrd1(+/-)), we discovered that lack of Lmbrd1 not only resulted in the increase of cardiac-glucose uptake, pathological consequences were also observed. The results suggested that Lmbrd1 gene not only plays a significant role in mediating the energy homeostasis in cardiac tissue, it may also be a key factor in the regulation of cardiac function in mice.

  2. the physiological function of LMBRD1 during embryogenesis, is reported.

  3. LMBD1 plays an imperative role in mediating and regulating the endocytosis of the IR.

LMBR1 Domain Containing 1 (LMBRD1) Antigen Profile

Protein Summary

This gene encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. This protein also interacts with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F.

Gene names and symbols associated with LMBRD1

  • LMBR1 domain containing 1 (lmbrd1) antibody
  • LMBR1 domain containing 1 (LMBRD1) antibody
  • LMBR1 domain containing 1 (MCYG_07794) antibody
  • LMBR1 domain containing 1 (Lmbrd1) antibody
  • LMBR1 domain containing 1 L homeolog (lmbrd1.L) antibody
  • 0910001K20Rik antibody
  • AV347960 antibody
  • C6orf209 antibody
  • fc08a03 antibody
  • LMBD1 antibody
  • MAHCF antibody
  • MGC89794 antibody
  • NESI antibody
  • wu:fc08a03 antibody
  • zgc:103471 antibody

Protein level used designations for LMBRD1

LMBR1 domain-containing protein 1 , probable lysosomal cobalamin transporter , LMBR1 domain containing 1 , HDAg-L-interacting protein NESI , hepatitis delta antigen-L interacting protein , liver regeneration p-53 related protein , nuclear export signal-interacting protein , protein N90b

GENE ID SPECIES
323720 Danio rerio
474955 Canis lupus familiaris
714710 Macaca mulatta
736319 Pan troglodytes
779630 Xenopus (Silurana) tropicalis
9226393 Arthroderma otae CBS 113480
100057167 Equus caballus
100153685 Sus scrofa
55788 Homo sapiens
68421 Mus musculus
246046 Rattus norvegicus
510495 Bos taurus
421874 Gallus gallus
398468 Xenopus laevis
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