LMBRD1 antibody (C-Term)

Catalog No. ABIN6991441

This Rabbit Polyclonal antibody specifically detects LMBRD1 in ELISA, WB, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LMBRD1 antibody (C-Term) (ABIN6991441)

Target: LMBRD1 (LMBR1 Domain Containing 1 (LMBRD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMBRD1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LMBRD1 Antibody

Binding Specificity: C-Term

Purification: LMBRD1 Antibody is affinity chromatography purified via peptide column.

Immunogen: LMBRD1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LMBRD1. The immunogen is located within the last 50 amino acids of LMBRD1.

Isotype: IgG

Application Details

Application Notes: LMBRD1 antibody can be used for detection of LMBRD1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: LMBRD1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: LMBRD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LMBRD1

Target: LMBRD1 (LMBR1 Domain Containing 1 (LMBRD1))

Alternative Name: LMBRD1

Background: LMBRD1 Antibody: LMBRD1, also known as NESI (nuclear export signal-interacting protein, is a lysosomal membrane protein that is thought be involved in the transport and metabolism of cobalamin. LMBRD1 was initially identified as interacting with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F (cblF).

Gene ID: 55788

NCBI Accession: NP_060838

UniProt: Q9NUN5