anti-Laminin, alpha 3 (LAMA3) Antibodies

Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Additionally we are shipping LAMA3 Kits (14) and LAMA3 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LAMA3 3909 Q16787
LAMA3 16774  
LAMA3 307582  
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Top anti-LAMA3 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 6 to 7 Days
$291.53
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using LAMA3 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using LAMA3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p) 100 μL Log in to see 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Human Kidney Tissue. 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemistry: Laminin alpha 3 Antibody (CL3112) [NBP2-42390] - Staining of human colon shows positivity in basement membrane of glandular epithelium. Immunohistochemistry: Laminin alpha 3 Antibody (CL3112) [NBP2-42390] - Staining of human lymph node shows absence of positivity in lymphoid tissue (negative control). 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: Laminin alpha 3 Antibody [NBP1-89955] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules. Immunocytochemistry/Immunofluorescence: Laminin alpha 3 Antibody  - Staining of human cell line A-431 shows localization to endoplasmic reticulum. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-LAMA3/Laminin 5 alpha 3 Polyclonal Antibody, Unconjugated (ABIN676073) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated ELISA, IF, IHC   100 μL Log in to see 16 Days
$181.73
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 11 to 14 Days
$507.83
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 7 to 9 Days
$375.73
Details

Top referenced anti-LAMA3 Antibodies

  1. Human Polyclonal LAMA3 Primary Antibody for ELISA - ABIN250910 : Dietze, Bowie, Mrózek, Caldwell, Neal, Marjoram, Troch, Bean, Yokoyama, Ibarra, Seewaldt: CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5. in Journal of cell science 2005 (PubMed)

  2. Human Polyclonal LAMA3 Primary Antibody for IHC, IHC (p) - ABIN4330106 : Kuhn, Kurman, Soslow, Han, Sehdev, Morin, Wang, Shih: The diagnostic and biological implications of laminin expression in serous tubal intraepithelial carcinoma. in The American journal of surgical pathology 2012 (PubMed)

More Antibodies against LAMA3 Interaction Partners

Horse (Equine) Laminin, alpha 3 (LAMA3) interaction partners

  1. A 6589-bp deletion spanning exons 24-27 was found in the LAMA3 gene in American Saddlebred foals born with the skin-blistering condition epitheliogenesis imperfecta

Human Laminin, alpha 3 (LAMA3) interaction partners

  1. The study has identified two mutations in two large consanguineous pedigrees. Identification of novel variants in the LAMA3 and PLEC genes will expand the mutation spectrum and also help in genetic counselling of patients in the Pakistani population.

  2. Seventeen percent of the patients were compound heterozygous or homozygous for mutations in the gene LAMA3, 59% carried mutations in both alleles of LAMB3, and 12% were homozygous for mutations in LAMC2. In nine patients with severe generalized JEB, detection of two mutations in one of the genes LAMA3, LAMB3, or LAMC2 was not possible, so the molecular basis of disease could not be clarified completely

  3. Both parents had offspring affected with JEB and displayed subtle enamel pitting of secondary dentition without any sign of skin blistering. The reported enamel abnormality in LAMA3 mutation carriers could be attributed to a half dose effect of the laminin a3 chain

  4. Loss of the normal basement membrane organization of alpha3 laminin observed in fibrotic regions from the lungs of patients with pulmonary fibrosis contributes to their disease progression.

  5. Two of the six genes (LAMA3 and DST) validated by quantitative RT-PCR for tumor-specific alternative splicing events

  6. LAMNA variants have been identified in atrial fibrillation cohort studies, demonstrating abnormalities in cardiac excitation - supra ventricular tachycardia and atrial fibrillation.

  7. We established the LAMA3 gene as novel potential susceptibility gene for atopic dermatitis.

  8. Expression of a3, beta3 and beta2 cannot predict the prognosis. However, high expression of beta2 mRNA in HCC/non-cancerous liver correlated significantly with the absence of complete encapsulation, which is an important tumor invasiveness factor.

  9. Results describe a new pedigree identifying a novel mutation of LAMA3 in LOC syndrome

  10. A male patient with Herlitz junctional epidermolysis bullosa with a novel homozygosity for insertion LAMA3 Premature Termination Codon mutation is described. Both parents and his sibling were shown to be heterozygous carriers.

  11. High LAMA3 expression is associated with gastric cancer.

  12. proteolytic processing of laminin-5 influences its interaction with alpha3beta1 integrin

  13. The uncoordinated production of chains of ln-5 in allergic asthma could have a bearing on the poor epithelial cell anchorage in these patients.

  14. tumor cell migration on laminin-5 is inhibited by HYD1, a biologically active integrin-targeting peptide

  15. Ln-5 is an important regulator of ADPKD cell proliferation and cystogenesis; Ln-5 gamma(2) chain and Ln-5-alpha(6)beta(4) integrin interaction both contribute to these phenotypic changes

  16. Laminin-5 alone stimulates global changes in gene/protein expression in mesenchymal stem cells that lead to commitment of these cells to the osteogenic phenotype, and this correlates with extracellular matrix production.

  17. LM-332 is a crucial motility-promoting factor for B-CLL lymphocytes and is a potential constituent favoring the dissemination of B-CLL lymphocytes through vascular basement membranes and possibly lymph node compartments.

  18. The major contributions of laminin-5 to the resistance of the epidermis against frictional stress but also for basement membrane regeneration and repair of damaged skin are reflected by the phenotype of Herlitz junctional epidermolysis bullosa.

  19. Letter/Case Report: report novel LAMA3 mutations leading to enamel defects in epidermolysis bullosa.

  20. invasive breast cancer cells confer an anoikis-resistant phenotype on myofibroblasts during tissue remodeling by inducing laminin-332 upregulation and integrin beta4 neoexpression

Mouse (Murine) Laminin, alpha 3 (LAMA3) interaction partners

  1. the gradual disappearance of alpha3 chain-containing laminins along the dermal-epidermal junction and formation of subepidermal blisters like in congenital junctional epidermis bullosa.

  2. The expression of integrin-alpha6beta4 and laminin-5 (alpha3, beta3, gamma2) mRNAs was significantly higher on SA-treated c.p.Ti than on c.p.Ti and AO c.p.Ti disks after 3 days (P<0.05).

  3. Deletion of the Lama3 gene leads to abnormnal development of glomerular endothelial and mesangial cells.

  4. alpha3B chain was scarcely detected in the vessels of malignant skin cancers, though the gamma2 and beta3 chains were highly expressed in the cancer cells.

  5. immunofluorescence analyses revealed a basement membrane staining in epithelial tissue for LaNt alpha3 and LaNt alpha3 localized along the substratum-associated surface of cultured keratinocytes.

LAMA3 Antigen Profile

Protein Summary

Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with LAMA3

  • laminin subunit alpha 3 (LAMA3) antibody
  • laminin subunit alpha-3 (LOC100401798) antibody
  • laminin subunit alpha-3 (LOC100484669) antibody
  • laminin subunit alpha 3 (lama3) antibody
  • laminin, alpha 3 (Lama3) antibody
  • laminin subunit alpha 3 (Lama3) antibody
  • BM600 antibody
  • E170 antibody
  • LAMA3 antibody
  • lama3a antibody
  • Lama3B antibody
  • LAMNA antibody
  • LOCS antibody
  • [a]3B antibody

Protein level used designations for LAMA3

laminin, alpha 3 , laminin alpha 3 subunit , alpha3A chain laminin , laminin subunit alpha-3-like , BM600 150kD subunit , epiligrin 170 kda subunit , epiligrin alpha 3 subunit , epiligrin subunit alpha , kalinin 165kD subunit , kalinin subunit alpha , laminin subunit alpha-3 , laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin) , laminin-5 alpha 3 chain , laminin-5 subunit alpha , laminin-6 subunit alpha , laminin-7 subunit alpha , nicein 150kD subunit , nicein subunit alpha , nicein, 150kDa , laminin 5 alpha 3

GENE ID SPECIES
428524 Gallus gallus
455339 Pan troglodytes
480173 Canis lupus familiaris
701313 Macaca mulatta
791238 Equus caballus
100401798 Callithrix jacchus
100484669 Ailuropoda melanoleuca
100496680 Xenopus (Silurana) tropicalis
100511642 Sus scrofa
100540219 Meleagris gallopavo
100561436 Anolis carolinensis
3909 Homo sapiens
16774 Mus musculus
307582 Rattus norvegicus
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