This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane.
Gene names and symbols associated with Latrophilin 3 Proteins (LPHN3)
adhesion G protein-coupled receptor L3 (ADGRL3) antibody
adhesion G protein-coupled receptor L3 (LOC100554073) antibody
adhesion G protein-coupled receptor L3 (Adgrl3) antibody
Protein level used designations for Latrophilin 3 Proteins (LPHN3)