Left-Right Determination Factor 2 (LEFTY2) ELISA Kits

LEFTY2 encodes a member of the TGF-beta family of proteins. Additionally we are shipping LEFTY2 Antibodies (59) and LEFTY2 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LEFTY2 7044 O00292
LEFTY2 320202 P57785
Anti-Rat LEFTY2 LEFTY2 289316  
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Top LEFTY2 ELISA Kits at antibodies-online.com

Showing 2 out of 8 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 5.5 pg/mL 15.62 pg/mL - 1000 pg/mL 96 Tests Log in to see 13 to 16 Days
Human 1.95 pg/mL 7.8-500 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days

More ELISA Kits for LEFTY2 Interaction Partners

Human Left-Right Determination Factor 2 (LEFTY2) interaction partners

  1. LEFTY2 down-regulates MKi67 (show MKI67 ELISA Kits) expression and FAK (show PTK2 ELISA Kits) activity, up-regulates miR (show MLXIP ELISA Kits)-200a and E-cadherin (show CDH1 ELISA Kits), and is thus a powerful negative regulator of endometrial cell proliferation and migration.

  2. LEFTY2 regulates the expression and activity of ENaC (show SCNN1A ELISA Kits) in endometrial epithelial cells via SGK1 (show SGK1 ELISA Kits).

  3. Lefty A may account for the tumor suppressive activity of human adult stem cells.

  4. Findings suggest that Lefty2 is negatively modulated by miR (show MLXIP ELISA Kits)-302s in hESCs, which plays an important role in maintaining the balance between pluripotency and germ layer specification.

  5. findings show that the TGFB4 (ebaf) mRNA has distinct tumor specific expression

  6. nodal and the inhibitors of Nodal signaling, lefty-A and lefty-B, are down-regulated very early upon differentiation of human embryonic stem cells

  7. Addition of recombinant LEFTY-A to explants induced MMP-9 (show MMP9 ELISA Kits) in most samples, a response prevented by ovarian steroids.

  8. LEFTY proteins, which are known to play a major role during mouse gastrulation, are transiently expressed during human embryonic stem cell differentiation.

Zebrafish Left-Right Determination Factor 2 (LEFTY2) interaction partners

  1. results indicate that differential diffusivity is the major determinant of the differences in Nodal/Lefty range and provide biophysical support for reaction-diffusion models of activator/inhibitor-mediated patterning

  2. we find that Cyclops is specifically required for the maintenance of lefty1 (show LEFTY1 ELISA Kits) and lefty2 transcription

  3. study reports that microRNA-430 (miR (show MYLIP ELISA Kits)-430) dampens and balances the expression of the transforming growth factor-beta (TGF-beta) Nodal agonist squint and the TGF-beta (show TGFB1 ELISA Kits) Nodal antagonist lefty

Mouse (Murine) Left-Right Determination Factor 2 (LEFTY2) interaction partners

  1. LEFTY2 regulates the expression and activity of ENaC (show SCNN1A ELISA Kits) in endometrial epithelial cells via SGK1 (show SGK1 ELISA Kits).

  2. Results indicate that microRNA miR (show MLXIP ELISA Kits)-127 accelerates mesendoderm differentiation of embryonic stem cells through nodal signaling by targeting left-right determination factor 2 (Lefty2).

  3. Studies indicate that the pair of Nodal and Lefty (Lefty1 and Lefty2) has a conserved role in left-right asymmetry.

  4. Taken together, these results suggest that optimal expression of Lefty1 (show LEFTY1 ELISA Kits) and Lefty2 is critical for the balanced differentiation of mESCs into three germ layers.

  5. ectopic expression of the Nodal inhibitor Lefty2 in the node of Nodal(neo/+) embryos resulted in a phenotype similar to that of the Nodal(neo/neo) mutant

LEFTY2 Antigen Profile

Antigen Summary

This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with LEFTY2

  • left-right determination factor 2 (LEFTY2) antibody
  • lefty2 (lft2) antibody
  • left-right determination factor 2 (Lefty2) antibody
  • Left-right determination factor 2 (Lefty2) antibody
  • left-right determination factor 2 (LOC699676) antibody
  • left-right determination factor 2-like (LOC100232580) antibody
  • 6030463A22Rik antibody
  • atv2 antibody
  • AV214969 antibody
  • cb720 antibody
  • Ebaf antibody
  • Ebaf2 antibody
  • fe38b03 antibody
  • Lefta antibody
  • Leftb antibody
  • LEFTYA antibody
  • TGFB4 antibody
  • wu:fe38b03 antibody

Protein level used designations for LEFTY2

TGF-beta-4 , endometrial bleeding-associated factor , left-right determination factor A , protein lefty-2 , protein lefty-A , transforming growth factor beta-4 , endometrial bleeding associated factor , left-right determination factor B , left-right determination, factor A , protein lefty-B , left-right determination factor 2 , lefty , left-right determination factor 2-like

7044 Homo sapiens
30146 Danio rerio
320202 Mus musculus
534018 Bos taurus
100337677 Sus scrofa
289316 Rattus norvegicus
395529 Gallus gallus
457780 Pan troglodytes
699676 Macaca mulatta
100232580 Taeniopygia guttata
100435327 Pongo abelii
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