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LEFTY2 Products

(Left-Right Determination Factor 2 (LEFTY2))

Categories

This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2010].

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Featured LEFTY2 Categories

LEFTY2 Antibodies

High quality antibodies with extensive validation data.

LEFTY2 ELISA Kits

Reliable ELISA kits for a wide range of species.

LEFTY2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LEFTY2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7157970
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7185094
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, ICC, IF
Validations
  • (2)
Cat. No. ABIN6262947
Quantity 100 μL
Datasheet Datasheet

Recommended LEFTY2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957426
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN843141
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5656351
Quantity 96 tests
Datasheet Datasheet

Recommended LEFTY2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309300
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN7318717
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401626
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LEFTY2 products

Toh, Blagovic, Yu, Voldman: "Spatially organized in vitro models instruct asymmetric stem cell differentiation." in: Integrative biology : quantitative biosciences from nano to macro, Vol. 3, Issue 12, pp. 1179-87, (2011) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Yashiro, Saijoh, Sakuma, Tada, Tomita, Amano, Matsuda, Monden, Okada, Hamada: "Distinct transcriptional regulation and phylogenetic divergence of human LEFTY genes." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 5, Issue 5, pp. 343-57, (2000) (PubMed).

Synonyms and alternative names related to LEFTY2

left-right determination factor 2 (LEFTY2), left right determination factor 1 (Lefty1), lefty2 (lft2), left-right determination factor 2 (Lefty2), Left-right determination factor 2 (Lefty2), left-right determination factor 2 (LOC699676), left-right determination factor 2-like (LOC100232580), 6030463A22Rik, AI450052, atv2, AV214969, cb720, EBAF, Ebaf, Ebaf2, fe38b03, LEFTA, Lefta, Leftb, lefty, lefty-1, LEFTYA, Stra3, TGFB4, Tgfb4, wu:fe38b03

Protein level used designations for LEFTY2

  • TGF-beta-4
  • endometrial bleeding-associated factor
  • left-right determination factor A
  • protein lefty-2
  • protein lefty-A
  • transforming growth factor beta-4
  • left-right determination factor 1
  • left-right determination, factor B
  • protein lefty-1
  • stimulated by retinoic acid gene 3 protein
  • endometrial bleeding associated factor
  • left-right determination factor B
  • left-right determination, factor A
  • protein lefty-B
  • left-right determination factor 2
  • lefty
  • left-right determination factor 2-like
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