Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 Proteins (LGR5)

Orphan receptor. Additionally we are shipping LGR5 Antibodies (224) and LGR5 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LGR5 14160 Q9Z1P4
Rat LGR5 LGR5 299802  
LGR5 8549 O75473
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Top LGR5 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 60 to 65 Days
$6,628.57
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
Details
Yeast Human His tag   50 μg Log in to see 8 to 11 Days
$341.00
Details
Escherichia coli (E. coli) Human His tag   100 μg Log in to see 15 to 18 Days
$560.00
Details
HEK-293 Cells Human Fc Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$860.20
Details

LGR5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
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Human , , ,
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More Proteins for Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) Interaction Partners

Mouse (Murine) Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) interaction partners

  1. sorted Reg4 (show REG4 Proteins)(+) DCS cells promote organoid formation of single Lgr5(+) colon stem cells. DCS cells can be massively produced from Lgr5(+) colon stem cells in vitro by combined Notch (show NOTCH1 Proteins) inhibition and Wnt (show WNT2 Proteins) activation

  2. The Lgr5-expressing cells differentiate into hair cells in high yield.

  3. Single-cell transcript profiles reveal multilineage priming in early progenitors derived from Lgr5-expressing intestinal stem cells.

  4. Arrb1 (show ARRB1 Proteins) reduced the chemotherapy-induced Lgr5 stem cell apoptosis by inhibiting endoplasmic reticulum stress-mediated mitochondrial apoptotic signaling.

  5. demonstrates that Lgr5 cells give rise to both anterior and posterior taste buds during development, and are capable of regenerating posterior taste buds after injury induced by glossopharyngeal nerve transection

  6. Lgr5(+) chief cells are involved in maintaining the homeostatic stem cell pool. Define Lgr5(+) chief cells as a major cell-of-origin of gastric cancer.

  7. Stem cell plasticity enables hair regeneration following Lgr5(+) cell loss.

  8. role for Lgr5(+) cancer stem cells in primary and metastatic colon cancer

  9. Data show that both the number and relative position of Paneth cells and Lgr5+ cells are important for fission.

  10. RSPO (show RSPO1 Proteins)-LGR4 (show LGR4 Proteins)/5-ZNRF3 (show ZNRF3 Proteins)/RNF43 (show RNF43 Proteins) module controls metabolic liver zonation and is a hepatic growth/size rheostat during development, homeostasis and regeneration.

Human Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) interaction partners

  1. This study uncovers a novel cross-talk between LGR5 and TGFbeta (show TGFB1 Proteins) signaling in colon cancer and identifies LGR5 as a new modulator of TGFbeta (show TGFB1 Proteins) signaling able to suppress colon cancer metastasis.

  2. Data show that IKKalpha (show CHUK Proteins) directly bind to the promoters of LGR5, in turn, upregulating LGR5 expression through activation of STAT3 (show STAT3 Proteins) signaling pathway during cancer progression.

  3. Report the presence of aberrantly located LGR5(+) cells coexpressing epithelial markers in the stromal compartment of women with endometriosis. These cells have a statistically significantly different expression profile in deep-infiltrating endometriosis in comparison with other types of endometriosis, independent of the menstrual cycle phase.

  4. Arrb1 (show ARRB1 Proteins) reduced the chemotherapy-induced Lgr5 stem cell apoptosis by inhibiting endoplasmic reticulum stress-mediated mitochondrial apoptotic signaling.

  5. LGR5 signaling in gastric cancer cells.LGR5 crosstalk with FOXO1 (show FOXO1 Proteins) in gastric cancer cells.

  6. High LGR5 expression is associated with osteoarthritis.

  7. The LGR5 primarily functions via the IQGAP1-Rac1 pathway to strengthen cell-cell adhesion in normal adult crypt stem cells and colon cancer cells.

  8. Lgr5(+) chief cells are involved in maintaining the homeostatic stem cell pool. Define Lgr5(+) chief cells as a major cell-of-origin of gastric cancer.

  9. LGR5-expressing fraction of CD54 (show ICAM1 Proteins)+ cells represents gastric cancer CSCs, in which LGR5 is closely associated with stemness and EMT (show ITK Proteins) core genes

  10. clathrin-mediated endocytosis inhibition of the leucine-rich G protein-coupled receptor-5 (show XCR1 Proteins) diminishes cell fitness

LGR5 Protein Profile

Protein Summary

Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.

Gene names and symbols associated with LGR5

  • leucine-rich repeat containing G protein-coupled receptor 5 L homeolog (lgr5.L)
  • leucine rich repeat containing G protein coupled receptor 5 (Lgr5)
  • leucine rich repeat containing G protein-coupled receptor 5 (LGR5)
  • FEX protein
  • GPR49 protein
  • GPR67 protein
  • GRP49 protein
  • HG38 protein
  • lgr5-a protein
  • lgr5a protein

Protein level used designations for LGR5

leucine-rich repeat-containing G protein-coupled receptor 5 , leucine-rich repeat-containing G-protein coupled receptor 5A , leucine-rich repeat-containing G-protein coupled receptor 5a , G protein-coupled receptor 49 , G-protein coupled receptor 49 , follicle expressed hormone , leucine-rich repeat-containing G-protein coupled receptor 5 , orphan G-protein coupled receptor FEX , G-protein coupled receptor 67 , G-protein coupled receptor HG38 , orphan G protein-coupled receptor HG38

GENE ID SPECIES
100526795 Xenopus laevis
14160 Mus musculus
299802 Rattus norvegicus
8549 Homo sapiens
427867 Gallus gallus
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