More product categories related to LRP1B ELISA Kit
More ELISA Kits for LRP1B Interaction Partners
Human Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B) interaction partners
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LRP1B mutations are highly prevalent among the lung adenocarcinoma patients with COPD.
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Data show that overexpression of full-length mouse Lrp1b leads to impaired cellular proliferation, while humsn LRP1B knockdown has the opposite effect.
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that LRP1B interacted with DVL2, inhibited the interaction between DVL2 and Axin, and negatively regulated beta-catenin/TCF signaling
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LRP1B gene is a target for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma.
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LRP1B, BRD2 and CACNA1D are new candidate genes in fetal metabolic programming of newborns exposed to maternal hyperglycemia.
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LRP1B presents with frequent molecular alterations for glioblastoma patients; its deletion may impact patient outcome.
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Silencing of LRP1B altered the expression of focal adhesion complex-associated proteins, and Cdc42/RhoA activities.
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genetic association studies in Danish population: Quantitative metabolic phenotypes in obesity are associated with SNP in various genes: LRP1B (rs2890652) is associated with body mass index and insulin resistance.
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LRP1b shows restricted expression in human tissues and binds to several extracellular ligands, including fibrinogen and apoE--carrying lipoproteins
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Epigenomics and microRNAs inactivate LRP1B, a modulator of the extracellular environment of thyroid cancer cells, and it is deleted in neoplasms.
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LRP1B was hypermethylated in four gastric cancer cell lines, and low LRP1B mRNA expression was associated with high methylation levels in gastric cancer cell lines.
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results suggest that haplotypes in the gene LRP1B are significant/protective for successful aging without cognitive decline
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The LRP1B gene is a candidate tumor suppressor gene in urothelial cancer.
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LRP1B can function as a negative regulator of uPAR regeneration and cell migration.
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These findings reveal that low density lipoprotein receptor-related protein 1B is a novel binding partner of beta-amyloid precursor protein (APP) that functions to decrease APP processing to amyloid beta peptides.
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LRP1B modulates the catabolism of uPAR and PDGFR, affecting the migration of smooth muscle cells.
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Loss of LRP1B function in esophageal carcinogenesis most often occurs either by homozygous deletion or by transcriptional silencing through hypermethylation of its CpG island.
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Although mouse LRP1B expresses in the forms of both full-length receptor tail and an alternatively spliced form lacking a 33-amino acid insert, human LRP1B is expressed exclusively in the form of full-length receptor tail
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LRP1B functions as a receptor for Pseudomonas exotoxin.
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Frequent inactivation of LRP1B mainly occurs by means of epigenetic mechanisms in oral squamous cell carcinoma, which might play an important role in oral tumorigenesis.
Mouse (Murine) Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B) interaction partners
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Data show that overexpression of full-length mouse Lrp1b leads to impaired cellular proliferation, while human LRP1B knockdown has the opposite effect.
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C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-beta neurotoxicity
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the extracellular domains may function as a scavenger for signaling ligands or signal modulators in the extracellular space, thereby preserving signaling thresholds that are critical for embryonic development
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Results show that in contrast to LRP1, LRP1b-deficient mice develop normally, most likely due to its restricted expression pattern and functional compensation by LRP1 or other receptors.
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both halves of the LRP1B cytoplasmic tail contribute to a unique global conformation, which results in less efficient recognition by endocytic adaptors and a slow endocytosis rate.
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This study presents the possibility that LRP1B participates in signal transduction which PICK1 may regulate by inhibiting PKCalpha phosphorylation of LRP1B.
LRP1B Antigen Profile
Antigen Summary
LRP1B belongs to the low density lipoprotein (LDL) receptor gene family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands (Liu et al., 2001
Gene names and symbols associated with LRP1B
- LDL receptor related protein 1B (LRP1B) antibody
- LDL receptor related protein 1B (lrp1b) antibody
- low density lipoprotein-related protein 1B (deleted in tumors) (Lrp1b) antibody
- 9630004P12Rik antibody
- LRP-DIT antibody
- LRPDIT antibody
Protein level used designations for LRP1B
low density lipoprotein receptor-related protein 1B , low density lipoprotein-related protein 1B , low-density lipoprotein receptor-related protein 1B-like , LRP-1B , LRP-deleted in tumors , low density lipoprotein receptor related protein-deleted in tumor , low density lipoprotein-related protein 1B (deleted in tumors) , low-density lipoprotein receptor-related protein 1B , low-density lipoprotein receptor-related protein-deleted in tumor
GENE ID | SPECIES |
---|---|
721791 | Macaca mulatta |
100343646 | Oryctolagus cuniculus |
100402000 | Callithrix jacchus |
100468231 | Ailuropoda melanoleuca |
100485687 | Xenopus (Silurana) tropicalis |
100624047 | Sus scrofa |
53353 | Homo sapiens |
94217 | Mus musculus |
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