anti-Lymphocyte Antigen 75 (LY75) Antibodies

Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Additionally we are shipping Lymphocyte Antigen 75 Kits (8) and Lymphocyte Antigen 75 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LY75 17076 Q60767
LY75 4065 O60449
LY75 499800  
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Top anti-Lymphocyte Antigen 75 Antibodies at antibodies-online.com

Showing 10 out of 169 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Mouse Rat Un-conjugated FACS, IHC (fro) Rat anti CD205 / DEC-205 / LY75 NLDC145 0.1 mg 6 to 8 Days
$368.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD205 expression in MCF7 (A), SP2/0 (B), H9C2 (C), mouse lymph node (D) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Mouse Rat FITC FACS, IHC (fro) Table 1. Antigen distribution. 0.2 mg 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Available
$363.46
Details
Mouse Rat Biotin FACS, IHC (fro) Rat anti CD205 / DEC-205 / LY75 NLDC145 0.15 mg 6 to 8 Days
$390.50
Details
Human Mouse PE FACS, IHC (f), WB Surface staining of human peripheral blood monocytes with anti-CD205 (HD30) PE. 100 Tests 5 to 7 Days
$497.45
Details
Cow Mouse FITC FACS   0.1 mg 6 to 8 Days
$621.50
Details
Human Mouse Un-conjugated IHC (fro), FACS, WB   0.1 mg 6 to 8 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of extracts from COLO205 cells, using LY75 antibody. ABIN6275874 staining COLO205 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated IHC (fro), FACS, IP 0.2 mg 3 to 4 Days
$433.53
Details

Top referenced anti-Lymphocyte Antigen 75 Antibodies

  1. Human Monoclonal LY75 Primary Antibody for FACS - ABIN2689082 : Guo, Gong, Maric, Misulovin, Pack, Mahnke, Nussenzweig, Steinman: A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells. in Human immunology 2000 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal LY75 Primary Antibody for FACS - ABIN2689081 : Kato, Neil, Clark, Morris, Sorg, Hart: cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells. in Immunogenetics 1998 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal LY75 Primary Antibody for IHC (fro), FACS - ABIN2479195 : Lopes: [Psychogenic sterility: a myth?]. in Revue française de gynécologie et d'obstétrique 1991 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal LY75 Primary Antibody for IHC (fro), FACS - ABIN2479201 : Kato, McDonald, Khan, Ross, Vuckovic, Chen, Munster, MacDonald, Hart: Expression of human DEC-205 (CD205) multilectin receptor on leukocytes. in International immunology 2006 (PubMed)
    Show all 4 Pubmed References

  5. Mouse (Murine) Monoclonal LY75 Primary Antibody for FACS - ABIN2479209 : Plavidal, Werch: Fetal scalp abscess secondary to intrauterine monitoring. in American journal of obstetrics and gynecology 1976 (PubMed)
    Show all 4 Pubmed References

  6. Mouse (Murine) Monoclonal LY75 Primary Antibody for FACS - ABIN2479207 : Di Rosa, Serafini, Scognamiglio, Di Virgilio, Finocchi, Aloisi, Barnaba: Short-lived immunization site inflammation in self-limited active experimental allergic encephalomyelitis. in International immunology 2000 (PubMed)
    Show all 4 Pubmed References

  7. Mouse (Murine) Monoclonal LY75 Primary Antibody for IHC (fro), FACS - ABIN2479206 : Kronin, Wu, Gong, Nussenzweig, Shortman: DEC-205 as a marker of dendritic cells with regulatory effects on CD8 T cell responses. in International immunology 2000 (PubMed)
    Show all 4 Pubmed References

  8. Mouse (Murine) Monoclonal LY75 Primary Antibody for FACS - ABIN2479210 : Serafini, Columba-Cabezas, Di Rosa, Aloisi: Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis. in The American journal of pathology 2000 (PubMed)
    Show all 4 Pubmed References

  9. Mouse (Murine) Monoclonal LY75 Primary Antibody for ICC, FACS - ABIN786567 : Flores-Langarica, Meza-Perez, Calderon-Amador, Estrada-Garcia, Macpherson, Lebecque, Saeland, Steinman, Flores-Romo: Network of dendritic cells within the muscular layer of the mouse intestine. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 2 Pubmed References

  10. Mouse (Murine) Monoclonal LY75 Primary Antibody for ICC, FACS - ABIN786569 : Rochereau, Verrier, Pin, Genin, Paul: Phenotypic localization of distinct DC subsets in mouse Peyer Patch. in Vaccine 2011 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Lymphocyte Antigen 75 Interaction Partners

Mouse (Murine) Lymphocyte Antigen 75 (LY75) interaction partners

  1. this study shows that CD205-TLR9-IL-12 axis contributes to CpG-induced oversensitive liver injury in Hepatitis B viral antigens transgenic mice by promoting the interaction of NKT cells with Kupffer cells

  2. Antigen targeting to DEC-205 on dendritic cells leads to an IL-10-dependent downregulation of CXCR3 expression on differentiated antigen-specific Th1 cells in vivo. This downregulation interferes with the migration of Th1 cells into the gut and protects mice against severe acute and relapsing intestinal inflammation.

  3. DNA vaccines encoding DEC205-targeted antigens induce peripheral tolerance rather than immunity

  4. The DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8 T cells independently of PD-1 and PD-L1.

  5. Through analysis of both polyclonal and monoclonal transgenic TCR T-cell development in the context of CD205 deficiency, we demonstrate that CD205 does not play an overt role in T cell development or selection.

  6. Introduction of a labile dipeptide linker at the N terminus of a T-cell epitope improves proteasome-dependent class I MHC-restricted peptide cross-presentation when delivered by alphaDEC205 in vitro and in vivo.

  7. Data indicate that the interaction between the PE-Cy5.5 conjugates and the cells expressing mDEC205 appears distinctive, since none of the PE-Cy5.5 conjugates bind to the cells that express human DEC205 on surface.

  8. CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo

  9. Langerin-positive dendritic cells appear to be the predominant, though not exclusive, population responsible for in vivo transport of anti-DEC-205 antibodies from the skin to the draining lymph nodes in steady state and inflammation.

  10. For production of cytotoxic T cells, DEC-205 and Clec9A, but not Clec12A, are effective targets for antibody-mediated delivery of antigens for vaccination, although only in the presence of adjuvants.

  11. Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

  12. show that Flt3L DC efficiently crosspresent HIV gag via the DEC-205 receptor, about 100 times more effective than non-targeted gag.

  13. Results suggest that DEC-205 provides an efficient receptor-based mechanism for dendritic cells to process proteins for MHC class I presentation in vivo, leading to tolerance in the steady state and immunity after dendritic cell maturation.

  14. This protein was detected in mouse Langerhans cells on epidermis separated by microwave irradiation.

  15. Dendritic cell targeting via the DEC205 receptor in the presence of anti-CD40 and poly(I:C) as maturation stimuli, induced strong human and mouse survivin-specific CD4+ T cell responses

  16. murine DEC-205 is a receptor for PLA of Yersinia pestis

  17. CD205 acts as a recognition receptor for dying cells, potentially providing an important pathway for the uptake of self-antigen in intrathymic and peripheral tolerance.

Human Lymphocyte Antigen 75 (LY75) interaction partners

  1. combined panel had the highest sensitivity and specificity at 96.3% and 100%, which was significantly or marginally higher than those of EZH2, C-KIT, and CD205 alone

  2. keratins are the cellular ligands of human DEC205.

  3. High LY75 expression is associated with metastasis of ovarian cancer.

  4. IL-6, DEC205, and CD86 can be predictive biomarkers for the respiratory and immune effects of ambient PM2.5.

  5. LY75 Gene Polymorphisms are Associated with Inflammatory Bowel Disease.

  6. results suggest that DEC205 is an immune receptor that recognizes apoptotic and necrotic cells specifically through a pH-dependent mechanism

  7. Variants in LY75 were associated with a Crohn's disease phenotype involving erythema nodosum.

  8. elevated in cholesteatoma

  9. DEC-205 is a cell surface receptor for CpG olligonucleotides.

  10. Data indicate that the interaction between the PE-Cy5.5 conjugates and the cells expressing mDEC205 appears distinctive, since none of the PE-Cy5.5 conjugates bind to the cells that express human DEC205 on surface.

  11. The most significantly associated SNPs to type 2 diabetes mellitus in this study are expression SNPs to the lymphocyte antigen 75 gene, the ubiquitin-specific peptidase 36 gene, and the phosphatidylinositol transfer protein, cytoplasmic 1 gene.

  12. CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo

  13. Upregulation of LY75 is associated with ovarian tumor.

  14. observed that TLR-mediated signaling increases DEC-205 expression levels without affecting receptor internalization

  15. Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1

  16. DCs and DEC-205 can cross-present several different peptides from a single protein. Data supports testing of alphaDEC-205 fusion mAb as a protein-based vaccine.

  17. CD205 is a sensitive and specific marker for thymoma but its sensitivity to thymic carcinoma is lower than CD5 and CD117.

  18. targeting EBV nuclear antigen 1 to human DEC-205 receptor, in the presence of the DC maturation stimulus poly(I:C), expanded EBNA1-specific CD4 and CD8 memory T cells; these lymphocytes control the outgrowth of autologous EBV-infected B cells

  19. oxLDL uptake by DCs is mediated by the scavenger-receptors LOX-1, CD36, and CD205

  20. Induction of LY75 antigen is associated with relapsed chronic myeloid leukemia.

Lymphocyte Antigen 75 (LY75) Antigen Profile

Protein Summary

Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.

Gene names and symbols associated with LY75

  • lymphocyte antigen 75 (LY75) antibody
  • lymphocyte antigen 75 (Cyan7822_2917) antibody
  • lymphocyte antigen 75 (LY5) antibody
  • lymphocyte antigen 75 (ly75) antibody
  • CD205 protein (cd205) antibody
  • lymphocyte antigen 75 (LOC100380704) antibody
  • CD302 antigen (LOC100433861) antibody
  • lymphocyte antigen 75 (LOC100483541) antibody
  • lymphocyte antigen 75 (Ly75) antibody
  • CD205 antibody
  • CLEC13B antibody
  • DEC-205 antibody
  • DEC205 antibody
  • GP200-MR6 antibody
  • im:7150926 antibody
  • Ly-75 antibody
  • LY75 antibody
  • LYT75 antibody
  • MGC140308 antibody
  • RGD1565962 antibody
  • si:dkey-78p20.2 antibody

Protein level used designations for LY75

lymphocyte antigen 75 , DEC-205/CD205 protein , DEC-205/CD205 , CD205 protein , DEC-205 protein , Lymphocyte antigen 75 , lymphocyte antigen 75-like , ly-75 , C-type lectin domain family 13 member B

GENE ID SPECIES
407236 Bos taurus
9739406 Cyanothece sp. PCC 7822
100060284 Equus caballus
100500738 Oncorhynchus mykiss
100462946 Takifugu rubripes
424192 Gallus gallus
459682 Pan troglodytes
488366 Canis lupus familiaris
504036 Danio rerio
595126 Sus scrofa
100101125 Felis catus
100380704 Salmo salar
100433861 Pongo abelii
100483541 Ailuropoda melanoleuca
17076 Mus musculus
4065 Homo sapiens
499800 Rattus norvegicus
101830769 Mesocricetus auratus
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