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Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. Additionally we are shipping Lysophospholipase I Proteins (19) and Lysophospholipase I Kits (4) and many more products for this protein.
Showing 10 out of 65 products:
Human Polyclonal LYPLA1 Primary Antibody for ELISA, WB - ABIN564540
Vose, Fujioka, Gulevich, Lin, Holland, Casida: Cellular function of neuropathy target esterase in lysophosphatidylcholine action. in Toxicology and applied pharmacology 2008
Human Monoclonal LYPLA1 Primary Antibody for IF, ELISA - ABIN523832
Hirano, Kishi, Sugimoto, Taguchi, Obinata, Ohshima, Tatei, Izumi: Thioesterase activity and subcellular localization of acylprotein thioesterase 1/lysophospholipase 1. in Biochimica et biophysica acta 2009
Data show taht active S-depalmitoylation in mitochondria, in part mediated by acyl-protein thioesterase 1 (APT1)
Here, we describe the conserved functions of APT1 (show FAS Antibodies) and APT2 (show TAP2 Antibodies) across organisms and discuss the possibility that these enzymes are members of a larger family of depalmitoylation enzymes.
High expression of APT1 (show FAS Antibodies) is associated with chronic lymphocytic leukemia.
identifcation APT1 (show FAS Antibodies) as one of the thioesterases in the acylation cycle and demonstration that this protein is a cellular target of the inhibitor.
Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 (show LYPLA2 Antibodies) with that of proto-oncogene (show RAB1A Antibodies) H-ras (show HRAS Antibodies) product and growth-associated protein-43 (show GAP43 Antibodies)
Serum activity of APT1 (show FAS Antibodies) may play an important role in determination of the concentration of des (show DES Antibodies)-acyl ghrelin (show GHRL Antibodies) in circulation, especially under septic inflammation.
Endogenous and overexpressed hAPT1 were mainly localized in the cytosol, while some signals were detected in the plasma membrane, the nuclear membrane and endoplasmic reticulum in HEK293 cells.
Results suggest that APT1 (show FAS Antibodies)-regulated depalmitoylation of Galpha (show SUCLG1 Antibodies)(13) might be an important downstream event of miR (show MLXIP Antibodies)-138 function.
Data indicate that thioesterases APT1 (show FAS Antibodies)/APT2 (show TAP2 Antibodies) depalmitoylate nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2 (show NMNAT2 Antibodies)) and zDHHC17 (show ZDHHC17 Antibodies) is the strongest candidate palmitoyltransferase for NMNAT2 (show NMNAT2 Antibodies).
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. The use of alternate polyadenylation sites has been found for this gene. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet.
acyl-protein thioesterase 1
, lysoPLA I
, lysophospholipid-specific lysophospholipase
, lysophopholipase 1
, lysophospholipase I
, phospholipase 1a
, lysophospholipase 1
, calcium-independent phospholipase A2