MDS1 and EVI1 Complex Locus Proteins
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters.
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MDS1 and EVI1 Complex Locus (MECOM) (AA 1-169) protein (His tag) Protein
MDS1 and EVI1 Complex Locus (MECOM) (AA 1-129) protein (His tag) Protein
MDS1 and EVI1 Complex Locus (MECOM) (AA 1-1051) protein (His tag) Protein
MDS1 and EVI1 Complex Locus (MECOM) (AA 1-1042) protein (His tag) Protein
MDS1 and EVI1 Complex Locus (MECOM) (AA 952-1050) protein (GST tag) Protein
MDS1 and EVI1 Complex Locus (MECOM) (AA 1-169) protein (GST tag) Protein
MDS1 and EVI1 Complex Locus (MECOM) (AA 80-169) protein (GST tag) Protein
MDS1 and EVI1 Complex Locus (MECOM) (AA 1-169) protein (His tag) Protein
MDS1 and EVI1 Complex Locus (MECOM) Protein Protein
MDS1 and EVI1 Complex Locus (MECOM) Protein Profile
Protein Summary
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Gene names and symbols associated with MECOM
- MDS1 and EVI1 complex locus (MECOM) antibody
- MDS1 and EVI1 complex locus (Mecom) antibody
- MDS1 and EVI1 complex locus (mecom) antibody
- MDS1 and EVI1 complex locus L homeolog (mecom.L) antibody
- AML1-EVI-1 antibody
- D630039M04Rik antibody
- evi-1 antibody
- evi1 antibody
- im:7140716 antibody
- Jbo antibody
- Mds antibody
- Mds1 antibody
- Mds1-Evi1 antibody
- mecom antibody
- mecom-a antibody
- mecom-b antibody
- prdm3 antibody
- xEvi-1 antibody
- Znfpr1b1 antibody
Protein level used designations for MECOM
AML1-EVI-1 fusion protein , MDS1 and EVI1 complex locus protein EVI1 , MDS1 and EVI1 complex locus protein MDS1 , ecotropic virus integration site 1 protein homolog , myelodysplasia syndrome-associated protein 1 , oncogene EVI1 , zinc finger protein Evi1 , ecotropic viral integration site 1 , ecotropic virus integration site 1 protein , myelodysplasia syndrome 1 homolog , myelodysplasia syndrome 1 protein homolog , PR domain containing 3 , MDS1 and EVI1 complex locus , MDS1 and EVI1 complex locus protein EVI1-like , MDS1 and EVI1 complex locus protein EVI1-A , ecotropic virus integration site 1 protein homolog-A , myelodysplasia syndrome 1-ectopic viral integration site 1
GENE ID | SPECIES |
---|---|
2122 | Homo sapiens |
424997 | Gallus gallus |
532209 | Bos taurus |
14013 | Mus musculus |
497407 | Danio rerio |
460837 | Pan troglodytes |
488148 | Canis lupus familiaris |
698603 | Macaca mulatta |
100343228 | Oryctolagus cuniculus |
100403987 | Callithrix jacchus |
100591579 | Nomascus leucogenys |
294924 | Rattus norvegicus |
734157 | Xenopus laevis |
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