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MDM2 Proteins

(Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))

This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues. [provided by RefSeq, Jul 2008].

recommended

MDM2 Protein (AA 1-491) (His tag) (ABIN7554539)

custom-made MDM2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

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recommended

MDM2 Protein (AA 1-489) (His tag) (ABIN7562986)

custom-made MDM2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

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recommended

MDM2 Protein (AA 1-491) (GST tag) (ABIN1310600)

MDM2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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MDM2 Proteins by Grade

Find MDM2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

MDM2 Proteins by Origin

Find MDM2 Proteins for a variety of species such as anti-Human MDM2, anti-Mouse MDM2, anti-Cat MDM2. The species listed below are among those available. Click on a link to go to the corresponding products.

MDM2 Proteins by Source

Here you will find MDM2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

MDM2 Proteins by Protein Type

Here you can find MDM2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

MDM2 Proteins by Application

Find MDM2 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

MDM2 Proteins by Biological Activity

Find MDM2 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular MDM2 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

MDM2 Protein (AA 1-491) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7554539

Quantity 1 mg

Datasheet Datasheet

MDM2 Protein (AA 1-489) (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7562986

Quantity 1 mg

Datasheet Datasheet

MDM2 Protein (AA 1-491) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1310600

Quantity 10 μg

Datasheet Datasheet

MDM2 Protein (AA 1-118) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123867

Quantity 50 μg

Datasheet Datasheet

MDM2 Protein (AA 1-300) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123866

Quantity 50 μg

Datasheet Datasheet

MDM2 Protein (AA 101-200) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1310602

Quantity 10 μg

Datasheet Datasheet

MDM2 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7578136

Quantity 100 μg

Datasheet Datasheet

MDM2 Protein (AA 1-310) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7408738

Quantity 100 μg

Datasheet Datasheet

MDM2 Protein (AA 1-321) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7408735

Quantity 100 μg

Datasheet Datasheet

MDM2 Protein (AA 1-489) (Strep Tag)

Reactivity Mouse

Source Cell-free protein synthesis (CFPS)

Validations

Cat. No. ABIN3133375

Quantity 250 μg

Datasheet Datasheet

MDM2 Protein (AA 1-491) (Strep Tag)

Reactivity Human

Source Cell-free protein synthesis (CFPS)

Validations

Cat. No. ABIN3093782

Quantity 250 μg

Datasheet Datasheet

MDM2 Protein (AA 1-489, full length) (His tag)

Reactivity Mouse

Source Yeast

Validations

Cat. No. ABIN5713638

Quantity 100 μg

Datasheet Datasheet

MDM2 Protein (AA 1-489, full length) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5709925

Quantity 100 μg

Datasheet Datasheet

MDM2 Protein (AA 1-218) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6239916

Quantity 50 μg

Datasheet Datasheet

MDM2 Protein (AA 1-118) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6700261

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our MDM2 Proteins

Zhang, Zhong, Chen: "LC-MS/MS-based targeted proteomics quantitatively detects the interaction between p53 and MDM2 in breast cancer." in: Journal of proteomics, Vol. 152, pp. 172-180, (2016) (PubMed).

Aliases for MDM2 Proteins

MDM2 proto-oncogene (MDM2) Proteins
MDM2 proto-oncogene S homeolog (mdm2.S) Proteins
MDM2 proto-oncogene (Mdm2) Proteins
Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) (MDM2) Proteins
MDM2 oncogene, E3 ubiquitin protein ligase (mdm2) Proteins
transformed mouse 3T3 cell double minute 2 (Mdm2) Proteins
1700007J15Rik Proteins
AA415488 Proteins
ACTFS Proteins
hdm2 Proteins
HDMX Proteins
Mdm-2 Proteins
zgc:109834 Proteins

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MDM2 Proteins by Grade

MDM2 Proteins by Origin

MDM2 Proteins by Source

MDM2 Proteins by Protein Type

MDM2 Proteins by Application

MDM2 Proteins by Biological Activity

Popular MDM2 Proteins

Latest Publications for our MDM2 Proteins

Aliases for MDM2 Proteins

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