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The protein encoded by MOB3B shares similarity with the yeast Mob1 protein.
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low levels of hMOB3B are closely associated with aggressive clinicopathologic features in patients with prostate cancer. The results suggest that hMOB3B may act as a tumor suppressor in human prostate cancer.
The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene.
MOB1, Mps One Binder kinase activator-like 2B
, mob1 homolog 2b
, monopolar spindle 1 binding, MOB1, domain containing
, mps one binder kinase activator-like 2B
, MOB1 (Mps One Binder) kinase activator-like 2B