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MPL ELISA Kits

(Myeloproliferative Leukemia Virus Oncogene (MPL))

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. The ligand for c-mpl, thrombopoietin, was cloned in 1994. Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated. [provided by RefSeq, Jul 2008].

recommended

MPL ELISA Kit (ABIN6957947)

MPL Reactivity: Human Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Lysate, Tissue Homogenate

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recommended

MPL ELISA Kit (ABIN1117542)

MPL Reactivity: Rat Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Plasma, Serum

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recommended

MPL ELISA Kit (ABIN5510636)

MPL Reactivity: Mouse AA 26-482 Colorimetric Sandwich ELISA

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MPL ELISA Kits by Reactivity

Find MPL ELISA Kits for a variety of species such as anti-Human MPL, anti-Mouse MPL, anti-Rat MPL. The species listed below are among those available. Click on a link to go to the corresponding products.

MPL ELISA Kits by Detection Method

Find MPL ELISA Kits with a specific Detection Method. The Detection Method listed below are among those available. Click on a link to go to the corresponding products.

MPL ELISA Kits by Analytical Method

Find MPL ELISA Kits with a specific Analytical Method. The Analytical Method listed below are among those available. Click on a link to go to the corresponding products.

MPL ELISA Kits by Method Type

Find MPL ELISA Kits with a specific Method Type. The Method Type listed below are among those available. Click on a link to go to the corresponding products.

MPL ELISA Kits by Sample

Find MPL ELISA Kits with a specific Sample. The Sample listed below are among those available. Click on a link to go to the corresponding products.

MPL ELISA Kits by Binding Specificity

Find MPL ELISA Kits with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Popular MPL ELISA Kits

Product

Reactivity

Analytical Method

Validations

Cat. No.

Quantity

Datasheet

MPL ELISA Kit

Reactivity Human

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6957947

Quantity 96 tests

Datasheet Datasheet

MPL ELISA Kit

Reactivity Rat

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN1117542

Quantity 96 tests

Datasheet Datasheet

MPL ELISA Kit

Reactivity Mouse

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN5510636

Quantity 96 tests

Datasheet Datasheet

MPL ELISA Kit

Reactivity Human

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6951177

Quantity 96 tests

Datasheet Datasheet

MPL ELISA Kit

Reactivity Mouse

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6730219

Quantity 96 tests

Datasheet Datasheet

Aliases for MPL ELISA Kits

MPL proto-oncogene, thrombopoietin receptor (MPL) ELISA Kits
myeloproliferative leukemia virus oncogene (Mpl) ELISA Kits
MPL proto-oncogene, thrombopoietin receptor (Mpl) ELISA Kits
MPL proto-oncogene, thrombopoietin receptor (mpl) ELISA Kits
C-MPL ELISA Kits
c-mpl ELISA Kits
c-mpl-I ELISA Kits
c-mpl-II ELISA Kits
CD110 ELISA Kits
hlb219 ELISA Kits
MPL ELISA Kits
mpll ELISA Kits
MPLV ELISA Kits
THCYT2 ELISA Kits
TPO-R ELISA Kits
TPOR ELISA Kits
tpor ELISA Kits
tpor.b ELISA Kits

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MPL ELISA Kits by Reactivity

MPL ELISA Kits by Detection Method

MPL ELISA Kits by Analytical Method

MPL ELISA Kits by Method Type

MPL ELISA Kits by Sample

MPL ELISA Kits by Binding Specificity

Popular MPL ELISA Kits

Aliases for MPL ELISA Kits

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