anti-Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1) Antibodies

The protein encoded by MST1 contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Additionally we are shipping MST1 Kits (48) and MST1 Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MST1 6789 Q13043
MST1 24566  
MST1 15235 P26928
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Top anti-MST1 Antibodies at antibodies-online.com

Showing 10 out of 102 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemistry with Liver tissue at an antibody concentration of 5µg/ml using anti-MST1 antibody (ARP45724_P050) WB Suggested Anti-MST1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB Host: Rabbit Target Name: MST1 Sample Type: Thymus Tumor lysates Antibody Dilution: 1.0ug/ml Rabbit Anti-MST1 Antibody Catalog Number: ARP45722_P050 Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue Observed Staining: Cytoplasm in hepatocytes Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB MST1 Antibody (C-term)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MST1 antibody detected the MST1 protein (arrow). MST1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MST1 Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB ABIN6270145 at 1/100 staining mouse heart tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6270145 at 1/100 staining rat heart tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Log in to see 11 to 12 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-MST1 Pab (ABIN392427) in HL60 cell lysate. MST1 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Western blot analysis of STK4 (arrow) using MST1 Antibody (C-term) (ABIN392427).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the STK4 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-CMST1 Polyclonal Antibody, Unconjugated (ABIN747308) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$306.90
Details
Dog Rabbit Un-conjugated IHC, IHC (p), WB Anti-MST1 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958312 concentration 5 ug/ml. Anti-MST1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms ... 50 μg Log in to see 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated IHC, WB ABIN6267141 at 1/100 staining Mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of WEHI-231 cells treated with Staurosporine, using Phospho-MST1 (Thr183)/MST2 (Thr180) Antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of NCI-H460 cells using MST1 Antibody (C-term) Cat.-No AP52761PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue reacted with MST1 Antibody (C-term) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining.This data demonstrates the use of MST1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB Western blot analysis of MST1 using 293 whole cell lysates ABIN6278391 at 1/100 staining Human pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details

Top referenced anti-MST1 Antibodies

  1. Human Polyclonal MST1 Primary Antibody for IHC (p), WB - ABIN392427 : Ren, Yan, You, Sun: Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells. in Cancer research 2008 (PubMed)
    Show all 2 Pubmed References

More Antibodies against MST1 Interaction Partners

Human Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1) interaction partners

  1. hWW45 (show SAV1 Antibodies) is required to enhance MST1-mediated apoptosis in vivo and thus is a critical player in an MST1-driven cell death signaling pathway.

  2. MST1-FOXO1 (show FOXO1 Antibodies) signaling is an important link survival factor deprivation-induced neuronal cell death

  3. hSav1 is a newly identified protein that interacts with Mst1 and augments Mst1-mediated apoptosis.

  4. tolerance to increased levels of intracellular ROS (show ROS1 Antibodies) provided by the Mst1-FoxOs signaling pathway is crucial for the maintenance of naive T cell homeostasis in the periphery

  5. The identified Mst1 as a binding partner that interacts with PHLPPs both in vivo and in vitro. PHLPPs dephosphorylate Mst1 on the T387 inhibitory site, which activate Mst1 and its downstream effectors p38 (show CRK Antibodies) and JNK (show MAPK8 Antibodies) to induce apoptosis.

  6. H2AX (show H2AFX Antibodies) is a substrate of MST1, which functions to induce apoptotic chromatin condensation and DNA fragmentation

  7. novel regulatory mechanism involving the phosphorylation of Sirt1 (show SIRT1 Antibodies) by MST1 kinase which leads to p53 (show TP53 Antibodies) activation, with implications for our understanding of signaling mechanisms during DNA damage-induced apoptosis

  8. Mst1 exhibits a growth promoting activity (show CNTF Antibodies) in HCC (show FAM126A Antibodies) cells upon NORE1B (show RASSF5 Antibodies) downregulation.

  9. Mst1 inactivates Prdx1 (show PRDX1 Antibodies) by phosphorylating it at Thr (show TRH Antibodies)-90 and Thr (show TRH Antibodies)-183, leading to accumulation of hydrogen peroxide in cells.

  10. Mst1 has an important role in inhibiting the growth of NSCLC in vitro and in vivo; its antiproliferative effect is associated with induction of apoptosis.

Mouse (Murine) Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1) interaction partners

  1. The results suggest that melatonin alleviates cardiac remodeling and dysfunction in diabetic cardiomyopathy by upregulating autophagy, limiting apoptosis, and modulating mitochondrial integrity and biogenesis. The mechanisms are associated with Mst1/Sirt3 (show SIRT3 Antibodies) signaling.

  2. These data suggest that MSP is an effective inhibitor of inflammation and lipid accumulation in the stressed liver, thereby indicating that MSP has a key regulatory role in non-alcoholic steatohepatitis.

  3. kinases, including Slk (show SLK Antibodies), Lok and Mst1, are inhibited by BI-D1870 but to a much lesser extent by BIX 02565 and that phosphorylation of some of their substrates is blocked by BI-D1870 in living cells.

  4. Nicorandil alleviates post-MI cardiac dysfunction and remodeling. The mechanisms were associated with enhancing autophagy and inhibiting apoptosis through Mst1 inhibition.

  5. Using a standard two-thirds partial hepatectomy (PH) model in young and aged mice, the activity of the core kinases MST1 and LATS1 increased during the early hypertrophic phase and returned to steady state levels in the proliferative phase, coinciding with activation of YAP1 (show YAP1 Antibodies) target genes and hepatocyte proliferation.

  6. The MST1 acts as a molecular brake to maintain immune tolerance by regulating T cell-mediated B cell activation (show BLNK Antibodies).

  7. Mst1 knockout alleviated while Mst1 overexpression aggravated cardiac dysfunction in diabetes.

  8. these findings highlight a role for MST1 in vesicle trafficking and extravasation in neutrophils, providing an additional mechanistic explanation for the severe immune defect

  9. Results identify L-plastin (show LCP1 Antibodies) as a key effector of Mst1 and establish a novel mechanism linking a signaling intermediate to an actin-binding protein (show PFN1 Antibodies) critical to T cell migration.

  10. MIST1 is a scaling factor necessary and sufficient by itself to induce and maintain secretory cell architecture

MST1 Antigen Profile

Protein Summary

The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.

Gene names and symbols associated with MST1

  • serine/threonine kinase 4 (STK4) antibody
  • macrophage stimulating 1 (MST1) antibody
  • macrophage stimulating 1 (Mst1) antibody
  • macrophage stimulating 1 (hepatocyte growth factor-like) (Mst1) antibody
  • macrophage stimulating 1 (hepatocyte growth factor-like) (MST1) antibody
  • macrophage stimulating 1 L homeolog (mst1.L) antibody
  • d3f15s2 antibody
  • D3F15S2h antibody
  • D9H3F15S2 antibody
  • dnf15s2 antibody
  • DNF15S2h antibody
  • E1A antibody
  • E2F2 antibody
  • HGF1/MSP antibody
  • hgfl antibody
  • KRS2 antibody
  • msp antibody
  • mst1 antibody
  • nf15s2 antibody
  • TIIAC antibody
  • XHL antibody
  • YSK3 antibody

Protein level used designations for MST1

MST-1 , STE20-like kinase MST1 , dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2)) , kinase responsive to stress 2 , mammalian STE20-like protein kinase 1 , mammalian sterile 20-like 1 , serine/threonine-protein kinase 4 , serine/threonine-protein kinase Krs-2 , hepatocyte growth factor-like protein , hepatocyte growth factor-like protein homolog , macrophage-stimulating protein , D8h3f15s2 , E2F transcription factor 2 , MSP , macrophage stimulatory protein , hepatocyte growth factor-like/macrophage stimulating protein , macrophage stimulating 1 (hepatocyte growth factor-like) , 12S E1A , macrophage stimulating 1 L homeolog

GENE ID SPECIES
6789 Homo sapiens
4485 Homo sapiens
24566 Rattus norvegicus
15235 Mus musculus
484768 Canis lupus familiaris
514667 Bos taurus
396135 Gallus gallus
100734937 Cavia porcellus
100512987 Sus scrofa
379214 Xenopus laevis
Selected quality suppliers for anti-MST1 (MST1) Antibodies
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