Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) Proteins (MST1)

The protein encoded by MST1 contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Additionally we are shipping MST1 Antibodies (102) and MST1 Kits (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MST1 4485 P26927
MST1 24566  
MST1 15235 P26928
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Top MST1 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$723.00
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$225.40
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 2 to 3 Days
$814.00
Details
Escherichia coli (E. coli) Rat T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$720.00
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$352.75
Details
Insect Cells Human GST tag   10 μg Log in to see 3 to 4 Days
$310.00
Details
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
$412.19
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$582.75
Details

MST1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, ,
Rat (Rattus)

Mouse (Murine) ,
,

More Proteins for Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1) Interaction Partners

Human Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1) interaction partners

  1. Mst1 has an important role in inhibiting the growth of NSCLC in vitro and in vivo; its antiproliferative effect is associated with induction of apoptosis.

  2. These data suggest that MSP (show MSMB Proteins) is an effective inhibitor of inflammation and lipid accumulation in the stressed liver, thereby indicating that MSP (show MSMB Proteins) has a key regulatory role in non-alcoholic steatohepatitis.

  3. Identify MST1/MSP as a mitogen for tracheal basal cells.

  4. MSP (show MSMB Proteins) appears to promote the migration of fibroblasts, enhances collagen synthesis and remodeling, and effectively improves wound healing.

  5. Elevated serum levels of MST1 were found in subjects with excessive alcohol use.

  6. These results support the hypothesis that the alpha-chain (show FCGRT Proteins) of MSPalphabeta mediates RON (show MST1R Proteins) dimerization.

  7. functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele

  8. Results suggest that the [AA] genotype of the common MST1 variant rs3197999 enhances genetic risk of sporadic extrahepatic cholangiocarcinoma irrespective of primary sclerosing cholangitis status.

  9. MSP (show MSMB Proteins) may be one of the major determinants that affects the properties of tumor stroma and that produces a permissive microenvironment to promote cancer metastasis

  10. The present results refine the known genetic architecture in primary sclerosing cholangitis by confirming MST1 locus association.

Mouse (Murine) Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1) interaction partners

  1. data revealed that OSM (show OSM Proteins) alleviated postinfarction cardiac remodeling and dysfunction by enhancing cardiomyocyte autophagy. OSM (show OSM Proteins) holds promise as a therapeutic target in treating HF after MI through Obeta receptor by inhibiting Mst1 phosphorylation.

  2. The results identify Mst1 as a malefactor in the development of post-infarction cardiac injury and that it acts through the JNK (show MAPK8 Proteins)-Drp1 (show CRMP1 Proteins)-mitochondrial fission pathway.

  3. The results suggest that melatonin alleviates cardiac remodeling and dysfunction in diabetic cardiomyopathy by upregulating autophagy, limiting apoptosis, and modulating mitochondrial integrity and biogenesis. The mechanisms are associated with Mst1/Sirt3 (show SIRT3 Proteins) signaling.

  4. These data suggest that MSP is an effective inhibitor of inflammation and lipid accumulation in the stressed liver, thereby indicating that MSP has a key regulatory role in non-alcoholic steatohepatitis.

  5. kinases, including Slk (show SLK Proteins), Lok and Mst1, are inhibited by BI-D1870 but to a much lesser extent by BIX 02565 and that phosphorylation of some of their substrates is blocked by BI-D1870 in living cells.

  6. Nicorandil alleviates post-MI cardiac dysfunction and remodeling. The mechanisms were associated with enhancing autophagy and inhibiting apoptosis through Mst1 inhibition.

  7. Using a standard two-thirds partial hepatectomy (PH) model in young and aged mice, the activity of the core kinases MST1 and LATS1 increased during the early hypertrophic phase and returned to steady state levels in the proliferative phase, coinciding with activation of YAP1 (show YAP1 Proteins) target genes and hepatocyte proliferation.

  8. The MST1 acts as a molecular brake to maintain immune tolerance by regulating T cell-mediated B cell activation (show BLNK Proteins).

  9. Mst1 knockout alleviated while Mst1 overexpression aggravated cardiac dysfunction in diabetes.

  10. these findings highlight a role for MST1 in vesicle trafficking and extravasation in neutrophils, providing an additional mechanistic explanation for the severe immune defect

MST1 Protein Profile

Protein Summary

The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.

Gene names and symbols associated with MST1

  • macrophage stimulating 1 (MST1)
  • macrophage stimulating 1 (Mst1)
  • macrophage stimulating 1 (hepatocyte growth factor-like) (Mst1)
  • macrophage stimulating 1 (hepatocyte growth factor-like) (MST1)
  • macrophage stimulating 1 L homeolog (mst1.L)
  • d3f15s2 protein
  • D3F15S2h protein
  • D9H3F15S2 protein
  • dnf15s2 protein
  • DNF15S2h protein
  • E1A protein
  • E2F2 protein
  • HGF1/MSP protein
  • hgfl protein
  • msp protein
  • mst1 protein
  • nf15s2 protein
  • XHL protein

Protein level used designations for MST1

hepatocyte growth factor-like protein , hepatocyte growth factor-like protein homolog , macrophage-stimulating protein , D8h3f15s2 , E2F transcription factor 2 , MSP , macrophage stimulatory protein , hepatocyte growth factor-like/macrophage stimulating protein , macrophage stimulating 1 (hepatocyte growth factor-like) , 12S E1A , macrophage stimulating 1 L homeolog

GENE ID SPECIES
4485 Homo sapiens
24566 Rattus norvegicus
15235 Mus musculus
484768 Canis lupus familiaris
514667 Bos taurus
396135 Gallus gallus
100734937 Cavia porcellus
100512987 Sus scrofa
379214 Xenopus laevis
Selected quality suppliers for MST1 Proteins (MST1)
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