Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) Proteins (MST1)

The protein encoded by MST1 contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Additionally we are shipping MST1 Antibodies (116) and MST1 Kits (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MST1 6789 Q13043
MST1 24566  
MST1 15235 P26928
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top MST1 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$723.00
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 2 to 3 Days
$814.00
Details
Escherichia coli (E. coli) Rat T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$720.00
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$352.75
Details
Insect Cells Human GST tag   10 μg Log in to see 3 to 4 Days
$310.00
Details
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
$412.19
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$582.75
Details

MST1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, ,
Rat (Rattus)

Mouse (Murine) ,
,

More Proteins for Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1) Interaction Partners

Human Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1) interaction partners

  1. hWW45 (show SAV1 Proteins) is required to enhance MST1-mediated apoptosis in vivo and thus is a critical player in an MST1-driven cell death signaling pathway.

  2. MST1-FOXO1 (show FOXO1 Proteins) signaling is an important link survival factor deprivation-induced neuronal cell death

  3. hSav1 is a newly identified protein that interacts with Mst1 and augments Mst1-mediated apoptosis.

  4. tolerance to increased levels of intracellular ROS (show ROS1 Proteins) provided by the Mst1-FoxOs signaling pathway is crucial for the maintenance of naive T cell homeostasis in the periphery

  5. The identified Mst1 as a binding partner that interacts with PHLPPs both in vivo and in vitro. PHLPPs dephosphorylate Mst1 on the T387 inhibitory site, which activate Mst1 and its downstream effectors p38 (show CRK Proteins) and JNK (show MAPK8 Proteins) to induce apoptosis.

  6. H2AX (show H2AFX Proteins) is a substrate of MST1, which functions to induce apoptotic chromatin condensation and DNA fragmentation

  7. novel regulatory mechanism involving the phosphorylation of Sirt1 (show SIRT1 Proteins) by MST1 kinase which leads to p53 (show TP53 Proteins) activation, with implications for our understanding of signaling mechanisms during DNA damage-induced apoptosis

  8. Mst1 exhibits a growth promoting activity (show CNTF Proteins) in HCC (show FAM126A Proteins) cells upon NORE1B (show RASSF5 Proteins) downregulation.

  9. Mst1 inactivates Prdx1 (show PRDX1 Proteins) by phosphorylating it at Thr (show TRH Proteins)-90 and Thr (show TRH Proteins)-183, leading to accumulation of hydrogen peroxide in cells.

  10. Mst1 has an important role in inhibiting the growth of NSCLC in vitro and in vivo; its antiproliferative effect is associated with induction of apoptosis.

Mouse (Murine) Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) (MST1) interaction partners

  1. The results suggest that melatonin alleviates cardiac remodeling and dysfunction in diabetic cardiomyopathy by upregulating autophagy, limiting apoptosis, and modulating mitochondrial integrity and biogenesis. The mechanisms are associated with Mst1/Sirt3 (show SIRT3 Proteins) signaling.

  2. These data suggest that MSP is an effective inhibitor of inflammation and lipid accumulation in the stressed liver, thereby indicating that MSP has a key regulatory role in non-alcoholic steatohepatitis.

  3. kinases, including Slk (show SLK Proteins), Lok (show STK10 Proteins) and Mst1, are inhibited by BI-D1870 but to a much lesser extent by BIX 02565 and that phosphorylation of some of their substrates is blocked by BI-D1870 in living cells.

  4. Nicorandil alleviates post-MI cardiac dysfunction and remodeling. The mechanisms were associated with enhancing autophagy and inhibiting apoptosis through Mst1 inhibition.

  5. Using a standard two-thirds partial hepatectomy (PH) model in young and aged mice, the activity of the core kinases MST1 and LATS1 increased during the early hypertrophic phase and returned to steady state levels in the proliferative phase, coinciding with activation of YAP1 (show YAP1 Proteins) target genes and hepatocyte proliferation.

  6. The MST1 acts as a molecular brake to maintain immune tolerance by regulating T cell-mediated B cell activation (show BLNK Proteins).

  7. Mst1 knockout alleviated while Mst1 overexpression aggravated cardiac dysfunction in diabetes.

  8. these findings highlight a role for MST1 in vesicle trafficking and extravasation in neutrophils, providing an additional mechanistic explanation for the severe immune defect

  9. Results identify L-plastin (show LCP1 Proteins) as a key effector of Mst1 and establish a novel mechanism linking a signaling intermediate to an actin-binding protein (show PFN1 Proteins) critical to T cell migration.

  10. MIST1 is a scaling factor necessary and sufficient by itself to induce and maintain secretory cell architecture

MST1 Protein Profile

Protein Summary

The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.

Gene names and symbols associated with MST1

  • serine/threonine kinase 4 (STK4)
  • macrophage stimulating 1 (MST1)
  • macrophage stimulating 1 (Mst1)
  • macrophage stimulating 1 (hepatocyte growth factor-like) (Mst1)
  • macrophage stimulating 1 (hepatocyte growth factor-like) (MST1)
  • macrophage stimulating 1 L homeolog (mst1.L)
  • d3f15s2 protein
  • D3F15S2h protein
  • D9H3F15S2 protein
  • dnf15s2 protein
  • DNF15S2h protein
  • E1A protein
  • E2F2 protein
  • HGF1/MSP protein
  • hgfl protein
  • KRS2 protein
  • msp protein
  • mst1 protein
  • nf15s2 protein
  • TIIAC protein
  • XHL protein
  • YSK3 protein

Protein level used designations for MST1

MST-1 , STE20-like kinase MST1 , dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2)) , kinase responsive to stress 2 , mammalian STE20-like protein kinase 1 , mammalian sterile 20-like 1 , serine/threonine-protein kinase 4 , serine/threonine-protein kinase Krs-2 , hepatocyte growth factor-like protein , hepatocyte growth factor-like protein homolog , macrophage-stimulating protein , D8h3f15s2 , E2F transcription factor 2 , MSP , macrophage stimulatory protein , hepatocyte growth factor-like/macrophage stimulating protein , macrophage stimulating 1 (hepatocyte growth factor-like) , 12S E1A , macrophage stimulating 1 L homeolog

GENE ID SPECIES
6789 Homo sapiens
4485 Homo sapiens
24566 Rattus norvegicus
15235 Mus musculus
484768 Canis lupus familiaris
514667 Bos taurus
396135 Gallus gallus
100734937 Cavia porcellus
100512987 Sus scrofa
379214 Xenopus laevis
Selected quality suppliers for MST1 Proteins (MST1)
Did you look for something else?