anti-Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) Antibodies

The product of MGAT2 is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. Additionally we are shipping MGAT2 Kits (12) and MGAT2 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MGAT2 4247 Q10469
MGAT2 94273 Q09326
MGAT2 217664 Q921V5
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Top anti-MGAT2 Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MGAT2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate MGAT2 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-MGAT2 Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate Human kidney 100 μL 2 to 3 Days
$249.00
Details
Human Rabbit Un-conjugated FACS, WB MGAT2 Antibody (P423) (ABIN389038) western blot analysis in MCF-7 and HepG2 cell line lysates (35 µg/lane).This demonstrates the MGAT2 antibody detected the MGAT2 protein (arrow). 400 μL 10 to 11 Days
$385.00
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$507.83
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of Human liver cells, using MGAT2 antibody. 100 μL 11 to 13 Days
$366.77
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Rabbit APC IHC, ELISA   200 μL 11 to 14 Days
$1,013.83
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA   200 μL 11 to 14 Days
$1,013.83
Details
Human Rabbit FITC IHC, ELISA   200 μL 11 to 14 Days
$1,013.83
Details

Top referenced anti-MGAT2 Antibodies

  1. Human Polyclonal MGAT2 Primary Antibody for IHC (p), ELISA - ABIN545233 : Tan, Dunn, Jaeken, Schachter: Mutations in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development. in American journal of human genetics 1996 (PubMed)
    Show all 3 Pubmed References

More Antibodies against MGAT2 Interaction Partners

Human Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) interaction partners

  1. The recombinant hGnTII was purified from silkworm larval hemolymph in two steps by using tandem affinity purification tags, with a yield of approximately 120 mug from 10 mL hemolymph, and exhibited glycosyltransferase activity and strict substrate specificity. The enzyme was found to be N-glycosylated by the enzymatic cleavage of glycans, while hGnTII expressed in insect cells had not been reported to be glycosylated.

  2. These data suggest that substrate binding by MGAT2 employs both conserved and convergent catalytic subsite modules to provide substrate selectivity and catalysis. More broadly, the MGAT2 active-site architecture demonstrates how glycosyltransferases create complementary modular templates for regiospecific extension of glycan structures in mammalian cells.

  3. UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats).

  4. Golgi N-glycosyltransferases beta-1,2-N-acetylglucosaminyltransferase I, beta-1,2-N-acetylglucosaminyltransferase II, 1,4-galactosyltransferase I, and alpha-2,6-sialyltransferase I form both homo- and heterodimeric enzyme complexes in live cells

Mouse (Murine) Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) interaction partners

  1. the CD11c promoter was unexpectedly active and triggered Mgat2 deletion within multiple hematopoietic lineages, showed remarkably poor penetrance within native DC populations, and produced almost undetectable levels of green fluorescent protein signal. These findings show that the CD11c promoter is not DC-specific, and extreme care should be taken in the interpretation of data using any mouse created using the CD11c-CRE

  2. when the C-terminal cysteine (C334) was mutated, MGAT activity was actually higher than that of wild-type FL-MGAT2. Lastly, we determined that both transmembrane domains of MGAT2 are important for its ER localization, and that MGAT2 is present in mitochondrial-associated membranes.

  3. The use of 1-oleoyl-glycerol-d5 and (U13)C-TG oil followed by LC/ESI/MS/MS detection of stable-isotopic labeled DAG, TG, or glycerol provides a wide range of applications to study pathophysiological regulation of the monoacylglycerol pathway and MGAT2 activity.

  4. beneficial effects of vertical sleeve gastrectomy on body weight and glucose metabolism are independent of MGAT2 activity

  5. The results suggest that MGAT2 has a pivotal role in lipid metabolism in the small intestine, and the inhibition of MGAT2 activity may be a promising strategy for the treatment of obesity-related metabolic disorders.

  6. MGAT2 may play an important role in dietary fat absorption

  7. MGAT2 is a monoacylglycerol acyltransferase expressed in the small intestine

  8. investigated the expression of murine MGAT2 protein along the intestinal tract, determined its subcellular localization, and studied its regulation by diet and in db/db mouse

  9. analysis of developmental and nutritional regulation of monoacylglyceanalysis of developmental and nutritional regulation of monoacylglycerol lipase and monoacylglycerol acyltransferaserol lipase and monoacylglycerol acyltransferase

MGAT2 Antigen Profile

Protein Summary

The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.

Gene names and symbols associated with MGAT2

  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT2) antibody
  • CG7921 gene product from transcript CG7921-RB (Mgat2) antibody
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog (mgat2.L) antibody
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (mgat2) antibody
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat2) antibody
  • mannoside acetylglucosaminyltransferase 2 (Mgat2) antibody
  • AA407964 antibody
  • CDG2A antibody
  • CDGS2 antibody
  • CG7921 antibody
  • CH73-301C19.1 antibody
  • Dmel\\CG7921 antibody
  • dMGAT2 antibody
  • GlcNAc-TII antibody
  • GlcNAcT2 antibody
  • GLCNACTII antibody
  • GNT-II antibody
  • Gnt2 antibody
  • MGC89475 antibody
  • zgc:162268 antibody

Protein level used designations for MGAT2

Beta-1,2-N-acetylglucosaminyltransferase II , N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II , UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II , alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase , glcNAc-T II , mannoside acetylglucosaminyltransferase 2 , CG7921-PA , CG7921-PB , CG7921-PC , Mgat2-PA , Mgat2-PB , Mgat2-PC , mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase , alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like , GNT-II , beta-1,2-N-acetylglucosaminyltransferase II , beta-12-N-acetylglucosaminyltransferase II

GENE ID SPECIES
4247 Homo sapiens
43563 Drosophila melanogaster
414590 Xenopus laevis
448439 Xenopus (Silurana) tropicalis
480312 Canis lupus familiaris
706426 Macaca mulatta
740608 Pan troglodytes
100023862 Monodelphis domestica
100348676 Oryctolagus cuniculus
100403225 Callithrix jacchus
100460559 Pongo abelii
100469937 Ailuropoda melanoleuca
94273 Rattus norvegicus
100151745 Sus scrofa
217664 Mus musculus
101122525 Ovis aries
100724305 Cavia porcellus
100000478 Danio rerio
Selected quality suppliers for anti-MGAT2 (MGAT2) Antibodies
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