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MGAT2 antibody (Middle Region)

MGAT2 Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781980
  • Target See all MGAT2 Antibodies
    MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))
    Binding Specificity
    • 8
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 32
    • 14
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human, Mouse, Rat, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig
    Host
    • 37
    • 1
    Rabbit
    Clonality
    • 37
    • 1
    Polyclonal
    Conjugate
    • 18
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    This MGAT2 antibody is un-conjugated
    Application
    • 23
    • 20
    • 18
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    Immunohistochemistry (IHC), Western Blotting (WB)
    Sequence
    PKNAALKLGC INAEYPDSFG HYREAKFSQT KHHWWWKLHF VWERVKILRD
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against MGAT2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human MGAT2
    Top Product
    Discover our top product MGAT2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 447 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))
    Alternative Name
    MGAT2 (MGAT2 Products)
    Synonyms
    CDG2A antibody, CDGS2 antibody, GLCNACTII antibody, GNT-II antibody, GNT2 antibody, CG7921 antibody, Dmel\\CG7921 antibody, GlcNAc-TII antibody, GlcNAcT2 antibody, dMGAT2 antibody, MGC89475 antibody, Gnt2 antibody, AA407964 antibody, CH73-301C19.1 antibody, zgc:162268 antibody, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase antibody, CG7921 gene product from transcript CG7921-RB antibody, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog antibody, mannoside acetylglucosaminyltransferase 2 antibody, MGAT2 antibody, Mgat2 antibody, mgat2.L antibody, mgat2 antibody
    Background
    MGAT2 is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in its gene may lead to carbohydrate-deficient glycoprotein syndrome, type II.The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. Two transcript variants encoding the same protein have been identified for this gene.
    Alias Symbols: CDGS2, GLCNACTII, GNT-II, GNT2, CDG2A
    Protein Interaction Partner: UBC,
    Protein Size: 447
    Molecular Weight
    51 kDa
    Gene ID
    4247
    NCBI Accession
    NM_002408, NP_002399
    UniProt
    Q10469
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