anti-Mastermind-Like 2 (Drosophila) (MAML2) Antibodies

Acts as a transcriptional coactivator for NOTCH proteins. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAML2 270118  
MAML2 689844  
MAML2 84441 Q8IZL2
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Top anti-MAML2 Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  Maml2  Sample Type:  Mouse Stomach lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Guinea Pig Rabbit Un-conjugated WB WB Suggested Anti-5930431H10 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Mouse Kidney 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) . Dilution: 1:500~1000 100 μg Log in to see 8 to 11 Days
$461.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated FACS, IF, IHC (p) IHC testing of FFPE human bladder carcinoma with MAML2 antibody (clone MMLP2-1). IHC testing of FFPE human colon carcinoma with MAML2 antibody (clone MMLP2-1). 100 μg Log in to see 2 to 3 Days
$361.90
Details
Human Rabbit Un-conjugated IHC, IP, WB Western Blot and Immunoprecipitation: MAML2 Antibody [ABIN151565] - Detection of Human and Mouse MAML2 by Western Blot (h and m) and Immunoprecipitation (m). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-MAML2 antibody (Cat. No. ABIN151565) used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B), and used for IP at 3 mcg/mg lysate. MAML2 was also immunoprecipitated by another rabbit anti-MAML2 antibodies and (Cat. No. ABIN151564).  Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B). 0.1 mL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 16 Days
$149.09
Details
Human Mouse CF405M FACS, IF, IHC, ISt, WB   100 μL Log in to see 3 to 4 Days
$209.23
Details
Human Mouse CF®640R FACS, IF, IHC, ISt, WB   100 μL Log in to see 3 to 4 Days
$209.23
Details

Top referenced anti-MAML2 Antibodies

  1. Human Polyclonal MAML2 Primary Antibody for IHC, IP - ABIN151565 : Oyama, Harigaya, Sasaki, Okamura, Kokubo, Saga, Hozumi, Suganami, Tamura, Nagase, Koga, Nishimura, Sakamoto, Sato, Yoshida, Kitagawa: Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo. in Development (Cambridge, England) 2011 (PubMed)

More Antibodies against MAML2 Interaction Partners

Human Mastermind-Like 2 (Drosophila) (MAML2) interaction partners

  1. CRTC3 (show CRTC3 Antibodies)-MAML2 gene fusion occurs in hidradenomas.

  2. findings suggest further characterization of MECs is needed before considering the CRTC1 (show CRTC1 Antibodies)/3-MAML2 gene fusion as a prognostic biomarker

  3. It is, to our knowledge, the first case of B acute lymphoblastic leukemia with this fusion gene. At the molecular level, two rearrangements were detected using RNA sequencing juxtaposing exon 7 to exon 2 and exon 9 to intron 1-2 of the KMT2A (show MLL Antibodies) and MAML2 genes respectively, and one rearrangement using Sanger sequencing juxtaposing exon 8 and exon 2.

  4. we demonstrated that MDM2 (show MDM2 Antibodies) is frequently overexpressed in clear cell carcinomas, and that MDM2 (show MDM2 Antibodies) overexpression is associated with poor prognosis.

  5. Warthin-like mucoepidermoid carcinoma (MEC (show CCL28 Antibodies)), and now a ciliated form of MEC (show CCL28 Antibodies), are newly described variants of a common salivary gland carcinoma. MAML2 rearrangements were identified in all cases. These unusual variants appear to consistently harbor MAML2 fusions-a finding that establishes a clear link to conventional MEC (show CCL28 Antibodies).

  6. MECT1 (show CRTC1 Antibodies)-MAML2 fusion transcript is a driver genetic event in the pathogenesis of primary bronchopulmonary mucoepidermoid carcinoma

  7. A subgroup of MAML2 fusion-negative mucoepidermoid carcinomas are actually clear cell carcinoma of the salivary gland with EWSR1 (show EWSR1 Antibodies) translocation.

  8. This condensed chromatin structure is associated with binding of DNMT3B (show DNMT3B Antibodies) and decreased occupancy of OCT1 (show POU2F1 Antibodies) transcription factor at MAML2 enhancer, suggesting a role of DNMT3B (show DNMT3B Antibodies) in increasing methylation of MAML2 after stilbenoid treatment.

  9. revealing neither correlation between the cellular composition and CRTC1 (show CRTC1 Antibodies)-MAML2 fusions nor presence of CRTC3 (show CRTC3 Antibodies)-MAML2 fusions in cutaneous hidradenoma

  10. MAML2 rearrangement is common and specific for MEC (show CCL28 Antibodies), which makes it a useful diagnostic tool. MAML2 rearrangement also predicts a favorable prognosis.

MAML2 Antigen Profile

Protein Summary

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3 (By similarity).

Gene names and symbols associated with MAML2

  • mastermind like 2 (Drosophila) (Maml2) antibody
  • mastermind-like transcriptional coactivator 2 (Maml2) antibody
  • mastermind like transcriptional coactivator 2 (MAML2) antibody
  • 5930431H10 antibody
  • BC032967 antibody
  • MAM-3 antibody
  • MAM2 antibody
  • MAM3 antibody
  • MLL-MAML2 antibody

Protein level used designations for MAML2

mastermind like 2 , mastermind-like 2 , mastermind-like protein 2 , mam-2

GENE ID SPECIES
270118 Mus musculus
689844 Rattus norvegicus
84441 Homo sapiens
521194 Bos taurus
485116 Canis lupus familiaris
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