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MANF Antibodies

(Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors\; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related. [provided by RefSeq, Jun 2010].
MANF antibody  (AA 25-182) MANF antibody  (AA 25-182) MANF antibody (AA 25-182) (ABIN6143461)

MANF Reactivity: Human IF, IHC, IP, WB Host: Rabbit Polyclonal unconjugated

MANF antibody  (C-Term) MANF antibody  (C-Term) MANF antibody (C-Term) (ABIN6990751)

KO Validated MANF Reactivity: Human, Mouse, Rat ELISA, IF, IHC (p), WB Host: Rabbit Polyclonal unconjugated

MANF antibody  (N-Term) MANF antibody  (N-Term) MANF antibody (N-Term) (ABIN6656565)

MANF Reactivity: Human ELISA, FM, IHC, WB Host: Rabbit Polyclonal unconjugated

MANF Antibodies by Grade

Find MANF Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

MANF Antibodies by Reactivity

Find MANF Antibodies for a variety of species such as anti-Human MANF, anti-Mouse MANF, anti-Rat MANF. The species listed below are among those available. Click on a link to go to the corresponding products.

MANF Antibodies by Application

Find MANF Antibodies validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

MANF Antibodies by Host

Find MANF Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

MANF Antibodies by Binding Specificity

Find MANF Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MANF Antibodies by Clonality

Find available monoclonal or polyclonal MANF Antibodies. Click on a link to go to the corresponding products.

MANF Antibodies by Clone

Find MANF Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

MANF Antibodies by Conjugate

Find MANF Antibodies with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MANF Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IF, IHC, IP, WB
Validations
  • (7)
Cat. No. ABIN6143461
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN6990751
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA, FM, IHC, WB
Validations
  • (3)
Cat. No. ABIN6656565
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FM, IHC, WB
Validations
  • (3)
Cat. No. ABIN6656564
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF, ELISA, WB
Validations
  • (3)
Cat. No. ABIN521690
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7159417
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (4)
  • (1)
Cat. No. ABIN956417
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ICC, IF, WB
Validations
  • (2)
Cat. No. ABIN2855274
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, WB
Validations
  • (2)
Cat. No. ABIN1859738
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
Cat. No. ABIN2788136
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN500226
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN500224
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC, WB
Validations
  • (2)
Cat. No. ABIN7043330
Quantity 25 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN238606
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application IHC, WB
Validations
  • (1)
Cat. No. ABIN1841901
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our MANF Antibodies

Herranen, Ikäheimo, Lankinen, Pakarinen, Fritzsch, Saarma, Lindahl, Pirvola: "Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss." in: Cell death & disease, Vol. 11, Issue 2, pp. 100, (2020) (PubMed).

Lindahl, Chalazonitis, Palm, Pakarinen, Danilova, Pham, Setlik, Rao, Võikar, Huotari, Kopra, Andressoo, Piepponen, Airavaara, Panhelainen, Gershon, Saarma: "Cerebral dopamine neurotrophic factor-deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice." in: Neurobiology of disease, Vol. 134, pp. 104696, (2020) (PubMed).

Pakarinen, Danilova, Võikar, Chmielarz, Piepponen, Airavaara, Saarma, Lindahl: "MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System." in: eNeuro, Vol. 7, Issue 1, (2020) (PubMed).

Tseng, Danilova, Domanskyi, Saarma, Lindahl, Airavaara: "MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex." in: eNeuro, Vol. 4, Issue 5, (2018) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Chen, Sundvik, Rozov, Priyadarshini, Panula: "MANF regulates dopaminergic neuron development in larval zebrafish." in: Developmental biology, Vol. 370, Issue 2, pp. 237-49, (2012) (PubMed).

Lindholm, Voutilainen, Laurén, Peränen, Leppänen, Andressoo, Lindahl, Janhunen, Kalkkinen, Timmusk, Tuominen, Saarma: "Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo." in: Nature, Vol. 448, Issue 7149, pp. 73-7, (2007) (PubMed).

Petrova, Raibekas, Pevsner, Vigo, Anafi, Moore, Peaire, Shridhar, Smith, Kelly, Durocher, Commissiong: "MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons." in: Journal of molecular neuroscience : MN, Vol. 20, Issue 2, pp. 173-88, (2003) (PubMed).

Shridhar, Shridhar, Rivard, Siegfried, Pietraszkiewicz, Ensley, Pauley, Grignon, Sakr, Miller, Smith: "Mutations in the arginine-rich protein gene, in lung, breast, and prostate cancers, and in squamous cell carcinoma of the head and neck." in: Cancer research, Vol. 56, Issue 24, pp. 5576-8, (1997) (PubMed).

Shridhar, Rivard, Shridhar, Mullins, Bostick, Sakr, Grignon, Miller, Smith: "A gene from human chromosomal band 3p21.1 encodes a highly conserved arginine-rich protein and is mutated in renal cell carcinomas." in: Oncogene, Vol. 12, Issue 9, pp. 1931-9, (1996) (PubMed).

Aliases for MANF Antibodies

mesencephalic astrocyte derived neurotrophic factor (MANF) Antibodies
mesencephalic astrocyte-derived neurotrophic factor (Manf) Antibodies
RNA binding motif protein 15B (RBM15B) Antibodies
Mesencephalic astrocyte-derived neurotrophic factor (Manf) Antibodies
mesencephalic astrocyte-derived neurotrophic factor (manf) Antibodies
mesencephalic astrocyte derived neurotrophic factor (Manf) Antibodies
mesencephalic astrocyte-derived neurotrophic factor S homeolog (manf.S) Antibodies
3230402M22Rik Antibodies
AA407711 Antibodies
AA408789 Antibodies
AA673178 Antibodies
anon-EST:ParkEST188 Antibodies
ARMET Antibodies
Armet Antibodies
armet Antibodies
ARP Antibodies
arp Antibodies
ARP-like Antibodies
CG7013 Antibodies
D18Mgi17 Antibodies
D17914 Antibodies
Dmel\\CG7013 Antibodies
DmMANF Antibodies
im:6909481 Antibodies
MANF Antibodies
manf Antibodies
RBM15B Antibodies
zgc:153327 Antibodies
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