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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping MMP1 Kits (135) and MMP1 Proteins (54) and many more products for this protein.
Showing 10 out of 346 products:
Human Polyclonal MMP1 Primary Antibody for WB - ABIN3043405
Man, Gao, Zhang, Liu, Yan, Huang, Liu: Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma. in Cancer biology & therapy 2011
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Mouse (Murine) Polyclonal MMP1 Primary Antibody for IF (p), IHC (p) - ABIN668931
Luo, Zhang, Wang, Hu, Song, Zhang: The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model. in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2014
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Human Polyclonal MMP1 Primary Antibody for ELISA, IHC - ABIN4334917
Huu, Matsushita, Jin, Hamaguchi, Hasegawa, Takehara, Fujimoto: FTY720 ameliorates murine sclerodermatous chronic graft-versus-host disease by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin. in Arthritis and rheumatism 2013
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Human Monoclonal MMP1 Primary Antibody for ICC, FACS - ABIN969287
Genevay, Finckh, Mezin, Tessitore, Guerne: Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation. in Arthritis research & therapy 2010
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Human Polyclonal MMP1 Primary Antibody for IF (p), IHC (p) - ABIN668466
Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage. in Cells, tissues, organs 2012
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Human Monoclonal MMP1 Primary Antibody for FACS, IF - ABIN966588
Guan, Shu, Fu, Liu, Xu, Wu: Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells. in FEMS microbiology letters 2009
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Human Polyclonal MMP1 Primary Antibody for IHC (p), IP - ABIN948134
Kim, Xuan, Park: Licoricidin, an isoflavonoid isolated from Glycyrrhiza uralensis Fisher, prevents UVA-induced photoaging of human dermal fibroblasts. in International journal of cosmetic science 2016
Human Monoclonal MMP1 Primary Antibody for IHC (p), WB - ABIN2475718
Murray, Duncan, Arbuckle, Melvin, Fothergill: Matrix metalloproteinases and their inhibitors in gastric cancer. in Gut 1999
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Human Polyclonal MMP1 Primary Antibody for WB - ABIN517953
Teng, Wang, Hood, Conrads, Hamilton, Maxwell, Darcy, Conrads: Identification of candidate circulating cisplatin-resistant biomarkers from epithelial ovarian carcinoma cell secretomes. in British journal of cancer 2014
Human Monoclonal MMP1 Primary Antibody for FACS - ABIN4896251
Domeij, Modéer, Quezada, Yucel-Lindberg: Cell expression of MMP-1 and TIMP-1 in co-cultures of human gingival fibroblasts and monocytes: the involvement of ICAM-1. in Biochemical and biophysical research communications 2005
The current study indicated that MMP1 has a key role in the regulation of cervical tumor growth and lymph node metastasis via epithelial mesenchymal transition to a certain extent
2G allele of MMP-1, C allele of MMP-2 (show MMP2 Antibodies) and 5A/6A genotype of MMP-3 (show MMP3 Antibodies) are associated with susceptibility and disease progression of type 2 diabetic nephropathy
this study provides insights into the development of a possible alternative therapy manipulating MMP-1 and the mTOR (show FRAP1 Antibodies) signaling pathway in Epidermal growth factor receptor (show EGFR Antibodies)-tyrosine kinase (show RET Antibodies) inhibitor-resistant lung adenocarcinoma.
Specific silencing that targeted AMPK (show PRKAA1 Antibodies) resulted in the enhancement of mobility and contractility and in the production of MMP-1 and MMP-2 (show MMP2 Antibodies).
MMP-1 genotype may accelerate the development of HIV-associated neurocognitive disorder (HAND) whereas MMP3 (show MMP3 Antibodies) -1612 5A5A genotype may reduce the risk of pathogenesis of HAND.
Authors observed a significant increase in the immunoexpression of collagen I and III in patients with DCM and a significant reduction in the immunoexpression of MMP-1 compared with the control group. Also, the collagen I and TIMP-1 (show TIMP1 Antibodies) expression indicated a positive linear correlation and respectively a negative linear relationship with collagen III and MMP-1.
findings suggest that the polymorphic genotypes at MMP-1 promoter -1607 may play a major role in determining personal cancer susceptibility for prostate cancer in Taiwan
No significant association was found between MMP-1 (-16071G/2G, -519A/G) variants and obesity.
Reduced expression of types I and III collagen and TIMP-1 (show TIMP1 Antibodies) as well as the increased expression of MMP-1 and MMP-8 (show MMP8 Antibodies) in the anterior vaginal wall tissues play important roles in the onset of pelvic organ prolapse.
The results of the present study suggested that miR93 regulated MMP1 and collagen I expression in fibroblasts via calpain2. miR93 mediated collagen expression in stress urinary incontinence via calpain2.
the identification of MMP1 and MMP10 (show MMP10 Antibodies) genes in swine is reported.
increased interstitial MMP1 activity during ischemia and reperfusion is a result of the endothelin protein kinase c (show PKC Antibodies) pathway and may be due to enhanced phosphorylation of mmp1
Results indicate that leukemia inhibitory factor (LIF (show LIF Antibodies)) and Oncostatin M (show OSM Antibodies) increase the expression of MMP-1, MMP-3 (show MMP3 Antibodies), and TIMP-1 (show TIMP1 Antibodies) several fold, and that their expression is reduced to basal levels in the presence of the LIF (show LIF Antibodies) antagonist MH35-BD.
results suggest that Ubx regulates organ shape by controlling Mmp1 expression, and the extent and timing of extracellular matrix degradation.
This work identifies Draper-dependent activation of MMP-1 as a novel cascade required for proper glial clearance of severed axons.
Mmp1 negatively regulates ectopic eye differentiation by restricting the rate of proliferation and the levels of expression of retinal-determining genes dachshund and eyes absent.
Data indicate that matrix metalloproteinases mmp1 and mmp2 (show MMP2 Antibodies) mutants have distinct heart phenotypes.
These data demonstrate that Mmp1 modulates PDF processing, which leads to daily structural remodeling and circadian behavior.
A primary function of Mmp1, under the control of the JNK (show MAPK8 Antibodies) pathway, is to promote basement membrane repair, which in turn may permit cell migration and the restoration of a continuous tissue.
Drosophila Mmp1 is involved in the regulation of ISC proliferation for maintenance of gut (show GUSB Antibodies) homeostasis
Study identified three genes, regeneration (rgn (show RGN Antibodies)), augmenter of liver regeneration (alr (show GFER Antibodies)) and Matrix metalloproteinase-1 (Mmp1) expressed specifically in blastema cells during disc regeneration.
Infection with Mycobacterium bovis results in increase in interleukin-1alpha, TGF-beta1 (show TGFB1 Antibodies), and MMP1 in multinucleated macrophages.
MMP-2 (show MMP2 Antibodies) promoted and MMP-13 (show MMP13 Antibodies) disrupted vasculogenic mimicry formation in large cell lung cancer by cleaving laminin-5 to influence EGFR (show EGFR Antibodies) signal activation.
The data demonstrate that MMP13 (show MMP13 Antibodies) and CTGF (show CTGF Antibodies) play a crucial role in modulation of fibrogenic mediators while promoting hepatic fibrogenesis.
CXCL10 (show CXCL10 Antibodies) has strong inhibitory effects on neovascularization, whereas MMP13 (show MMP13 Antibodies) is required for neovascularization in C. albicans-infected corneas.
that MMP-13 (show MMP13 Antibodies) is a central protease in infarct development and cortical remodeling during post-stroke neurorepair
the phenotype seen in the Hdac4 (show HDAC5 Antibodies)(-/-) mice is partially derived from elevation in MMP-13 (show MMP13 Antibodies) and may be due to a bone remodeling disorder caused by overexpression of this enzyme.
MEF2C (show MEF2C Antibodies) is necessary for Mmp13 (show MMP13 Antibodies) gene expression at the transcriptional level and participates in PTH (show PTH Antibodies)-stimulated Mmp13 (show MMP13 Antibodies) gene expression by increased binding to c-FOS at the AP-1 (show JUN Antibodies) site in the Mmp13 (show MMP13 Antibodies) promoter.
data reveal a novel involvement of MMP-13 (show MMP13 Antibodies) in regulating dendritic cell (DC) immunobiology through moderating MHC-I surface presentation, endocytosis and cytokine/chemokine (show CCL1 Antibodies) secretion; furthermore, the reduced MHC-I surface presentation by DCs resulted in a poor CD8 (show CD8A Antibodies)(+) T-cell response in vitro; MMP-13 (show MMP13 Antibodies) might be a promising target for therapeutic intervention in inflammatory diseases
The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (show DDR2 Antibodies)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (show DDR2 Antibodies) and matrix metalloproteinase 13 (show MMP13 Antibodies).
Postnatal chondrocyte-specific deletion of Hdac3 (show HDAC3 Antibodies) with an inducible Col2a1 (show COL2A1 Antibodies)-Cre caused premature production of pErk1/2 and Mmp13 (show MMP13 Antibodies) in the growth plate.
BoHV-4 infection affects various pathways related to cell proliferation and cell surface integrity, at least three of which were centered on upregulation of matrix metalloproteinase 1 (MMP1). MMP1 transcription was upregulated by the BoHV-4 transactivator IE2/RTA (show RBM9 Antibodies), leading to abnormally high metalloproteinase tissue levels, potentially leading to defective endometrium healing and unresolved inflammation.
The expression patterns of MMP1, MMP2 (show MMP2 Antibodies), and MMP8 (show MMP8 Antibodies) were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1, MMP2 (show MMP2 Antibodies), and MMP8 (show MMP8 Antibodies) expression levels with meat quality traits were analyzed in cattle. The expression of MMP1, MMP2 (show MMP2 Antibodies), and MMP8 (show MMP8 Antibodies) were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.
Data suggest that luteolytic factors (such as interferon gamma (show IFNG Antibodies), tumor necrosis factor alpha (show TNF Antibodies), and PGF2a) control expression of MMP1, other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.
The results showed that a decrease in MMP-1 and MMP-2 (show MMP2 Antibodies) gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.
Cytoskeletal tension modulates MMP-1 gene expression from tenocytes on micropillar substrates.
MMP-1 promotes VEGFR2 (show KDR Antibodies) expression and proliferation of endothelial cells through stimulation of PAR-1 (show F2R Antibodies) and activation of NF-kappaB (show NFKB1 Antibodies)
These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.
the differential expression and localization of membrane-type 1 matrix metalloproteinase (show MMP14 Antibodies) in the corpus luteum suggest that it may have multiple functions throughout the course of the estrous cycle,including activation of pro-MMP-2 (show MMP2 Antibodies)
increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 and MMP-13 (show MMP13 Antibodies) (follicular apex (show APEX1 Antibodies) vs. base) for the preovulatory collagenolysis required for follicle rupture
identification of MT1-MMP (show MMP14 Antibodies) in odontoclasts during deciduous tooth resorption might be relevant to the migration activity that these cells have to gain access to the root surface
These results suggest that PEP-1-SIRT2 (show SIRT2 Antibodies) promotes matrix metalloproteinases-induced dedifferentiation via ERK (show MAPK1 Antibodies) signaling in articular chondrocytes. .
Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 and decreased TIMP-3 (show TIMP3 Antibodies) secretion.
ANXA2 (show ANXA2 Antibodies) and MMP1 might participate in remodeling during wound healing in the horse.
The polymorphism in the promoter of the MMP-1 gene could be a risk factor for early implant failure of total hip arthroplasty.
These results suggest that MMP-1 and IL-8 (show IL8 Antibodies) are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
, interstitial collagenase
, matrix metalloprotease 1
, matrix metalloproteinase 1
, matrix metalloproteinase 1 (type I collagenase)
, matrix metalloproteinase-1
, collagenase 3
, matrix metalloproteinase 13
, matrix metalloproteinase-13
, matrix metalloproteinase-18
, matrix metallopeptidase 1a
, matrix metalloproteinase 1a (interstitial collagenase)
, myocardial collagenase