anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Antibodies

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.

list all antibodies Gene Name GeneID UniProt
Anti-Human MMP1 MMP1 4312 P03956
Anti-Mouse MMP1 MMP1 17386 P33435
Anti-Rat MMP1 MMP1 300339  
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Top anti-MMP1 Antibodies at

Showing 10 out of 345 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
Horse Rabbit Un-conjugated IHC, WB WB Suggested Anti-MMP1 Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate <b>Sample Type:</b> Equine Cartilage Explants<br><b>Primary Dilution:</b> 1:800<br><b>Secondary Antibody</b>: Bio-Rad 170-5046 <br><b>Secondary Dilution:</b> 1:100,000<br>Image Submitted By: Adam Williams<br>University of Nottingham 100 μL Log in to see 2 to 3 Days
Human Mouse HRP EIA, IHC (fro), IHC (p), WB   1 mL Log in to see 6 to 8 Days
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-MMP1 Antibody Titration:  2.5ug/ml  Positive Control:  HT1080 cell lysate MMP1 is supported by BioGPS gene expression data to be expressed in HT1080 <b>Sample Type:</b> Human Macrophange Cells<br><b>Green:</b> primary<br><b>Red:</b> phallodin<br><b>Blue:</b> DAPI<br><b>Yellow:</b> green/red<br><b>Primary Dilution:</b> 1:200<br><b>Secondary Antibody:</b> anti-Rabbit IgG-FITC<br><b>Secondary Dilution: </b>1:1000<br><b>Image Submitted By:</b> Milan Fiala<br>University of California, Los Angeles 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image MMP1 antibody detects MMP1 protein at secreted on human endometrial carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human endometrial carcinoma. MMP1 antibody , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of MMP1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MMP1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
Human Mouse PE FACS Detection of MMP-1 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human MMP-1 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
Human Mouse Un-conjugated ELISA, FACS, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: MMP-1 Antibody (6A5) [NBP2-22123] - Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues (left) and human kidney cancer tissues (right) using MMP1 mouse mAb with DAB staining. Western Blot: MMP-1 Antibody (6A5) [NBP2-22123] - Western blot analysis using MMP1 mAb against HEK293 (1) and MMP1(AA: 24-213)-hIgGFc transfected HEK293 (2) cell lysate. 0.1 mL Log in to see 7 to 9 Days
Human Mouse Un-conjugated ELISA, FACS, IF, IHC, WB 100 μL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2 cells, using MMP-1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days

Top referenced anti-MMP1 Antibodies

  1. Human Polyclonal MMP1 Primary Antibody for WB - ABIN3043405 : Man, Gao, Zhang, Liu, Yan, Huang, Liu: Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma. in Cancer biology & therapy 2011 (PubMed)
    Show all 10 Pubmed References

  2. Mouse (Murine) Polyclonal MMP1 Primary Antibody for IF (p), IHC (p) - ABIN668931 : Luo, Zhang, Wang, Hu, Song, Zhang: The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model. in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2014 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal MMP1 Primary Antibody for ELISA, IHC - ABIN4334917 : Huu, Matsushita, Jin, Hamaguchi, Hasegawa, Takehara, Fujimoto: FTY720 ameliorates murine sclerodermatous chronic graft-versus-host disease by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin. in Arthritis and rheumatism 2013 (PubMed)
    Show all 4 Pubmed References

  4. Cow (Bovine) Polyclonal MMP1 Primary Antibody for IHC, ELISA - ABIN1582229 : Yang, Lee, Choi, Lee, Kim, Shin, Han, Kang, Chung: Matrix metalloproteinase-1 induces cleavage of exogenous alphaB-crystallin transduced by a cell-penetrating peptide. in Journal of cellular biochemistry 2011 (PubMed)
    Show all 4 Pubmed References

  5. Mouse (Murine) Polyclonal MMP1 Primary Antibody for IHC, ELISA - ABIN1586066 : Bonta, Matlung, Vos, Peters, Pannekoek, Bakker, de Vries: Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels. in Cardiovascular research 2010 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal MMP1 Primary Antibody for FACS, IF - ABIN966588 : Genevay, Finckh, Mezin, Tessitore, Guerne: Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation. in Arthritis research & therapy 2010 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal MMP1 Primary Antibody for ICC, FACS - ABIN969287 : Guan, Shu, Fu, Liu, Xu, Wu: Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells. in FEMS microbiology letters 2009 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal MMP1 Primary Antibody for IF (p), IHC (p) - ABIN668466 : Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage. in Cells, tissues, organs 2012 (PubMed)
    Show all 2 Pubmed References

  9. Human Monoclonal MMP1 Primary Antibody for FACS - ABIN4896251 : Domeij, Modéer, Quezada, Yucel-Lindberg: Cell expression of MMP-1 and TIMP-1 in co-cultures of human gingival fibroblasts and monocytes: the involvement of ICAM-1. in Biochemical and biophysical research communications 2005 (PubMed)

  10. Human Polyclonal MMP1 Primary Antibody for IHC (p), IP - ABIN948134 : Kim, Xuan, Park: Licoricidin, an isoflavonoid isolated from Glycyrrhiza uralensis Fisher, prevents UVA-induced photoaging of human dermal fibroblasts. in International journal of cosmetic science 2016 (PubMed)

More Antibodies against MMP1 Interaction Partners

Human Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. Review/Meta-analysis: MMP-1 -1607 1G/2G and MMP-12 (show MMP12 Antibodies) -82 A/G gene polymorphisms are associated with ischemic stroke risk.

  2. Results show that head and neck squamous cell carcinoma tumors with low P120CTN (show CTNND1 Antibodies) and PI3K (show PIK3CA Antibodies) pathway mutations have higher levels of MMP1 compared to tumors with high P120CTN (show CTNND1 Antibodies) and no PI3K (show PIK3CA Antibodies) pathway mutations demonstrating that P120CTN (show CTNND1 Antibodies) downregulation and PIK3CA (show PIK3CA Antibodies) mutations promote MMP1-driven invasion.

  3. MMP-1 (and MMP-2 (show MMP2 Antibodies) and MMP-3 (show MMP3 Antibodies)) are independently associated with markers of arterial stiffening in patients with type 1 diabetes.

  4. There was no statistically significant difference in the distribution of the MMP1-1607dupG (rs1799750) polymorphism between patients with unstable angina and the control group.

  5. PTEN inhibits replicative senescence-induced MMP-1 expression by regulating NOX4 (show NOX4 Antibodies)-mediated reactive oxygen species in human dermal fibroblasts.

  6. Matrix metalloproteinase 1 rs1799750 polymorphism was significantly associated with nasopharyngeal carcinoma risk in the subgroup analysis by smoking, a marginally significant association was found in non-smokers.

  7. Studied the association between the matrix metalloproteinase-1 (MMP-1) 1607 1G/2G polymorphism and susceptibility to spinal tuberculosis in Southern Chinese Han population.

  8. MMP1 was consistently and significantly upregulated in the induced pluripotent stem cells-derived endothelia from autosomal dominant polycystic kidney disease patients with intracranial aneurysms compared with the patients without intracranial aneurysms in multiple assays, indicating that high serum MMP1 levels may be a novel risk factor.

  9. cabozantinib suppressed MMP1 expression by blocking HGF (show HGF Antibodies)-MET signaling and that HGF (show HGF Antibodies)-MET-MMP1 signaling is involved in the invasiveness and proliferation of BCa (show BLNK Antibodies) cells. These results suggest that cabozantinib might prove useful for future treatment of muscle-invasive BCa (show BLNK Antibodies).

  10. rs1144393 in the MMP1 promoter region can be a predictor of grade >/= 2 RILI in lung cancer patients treated with thoracic radiation.

Pig (Porcine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. the identification of MMP1 and MMP10 (show MMP10 Antibodies) genes in swine is reported.

  2. increased interstitial MMP1 activity during ischemia and reperfusion is a result of the endothelin protein kinase c (show PKC Antibodies) pathway and may be due to enhanced phosphorylation of mmp1

  3. Results indicate that leukemia inhibitory factor (LIF (show LIF Antibodies)) and Oncostatin M (show OSM Antibodies) increase the expression of MMP-1, MMP-3 (show MMP3 Antibodies), and TIMP-1 (show TIMP1 Antibodies) several fold, and that their expression is reduced to basal levels in the presence of the LIF (show LIF Antibodies) antagonist MH35-BD.

Fruit Fly (Drosophila melanogaster) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. This work identifies Draper-dependent activation of MMP-1 as a novel cascade required for proper glial clearance of severed axons.

  2. Mmp1 negatively regulates ectopic eye differentiation by restricting the rate of proliferation and the levels of expression of retinal-determining genes dachshund and eyes absent.

  3. Data indicate that matrix metalloproteinases mmp1 and mmp2 (show MMP2 Antibodies) mutants have distinct heart phenotypes.

  4. These data demonstrate that Mmp1 modulates PDF processing, which leads to daily structural remodeling and circadian behavior.

  5. A primary function of Mmp1, under the control of the JNK (show MAPK8 Antibodies) pathway, is to promote basement membrane repair, which in turn may permit cell migration and the restoration of a continuous tissue.

  6. Drosophila Mmp1 is involved in the regulation of ISC proliferation for maintenance of gut (show GUSB Antibodies) homeostasis

  7. Study identified three genes, regeneration (rgn (show RGN Antibodies)), augmenter of liver regeneration (alr (show GFER Antibodies)) and Matrix metalloproteinase-1 (Mmp1) expressed specifically in blastema cells during disc regeneration.

Mouse (Murine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. CXCL10 (show CXCL10 Antibodies) has strong inhibitory effects on neovascularization, whereas MMP13 (show MMP13 Antibodies) is required for neovascularization in C. albicans-infected corneas.

  2. that MMP-13 (show MMP13 Antibodies) is a central protease in infarct development and cortical remodeling during post-stroke neurorepair

  3. the phenotype seen in the Hdac4 (show HDAC5 Antibodies)(-/-) mice is partially derived from elevation in MMP-13 (show MMP13 Antibodies) and may be due to a bone remodeling disorder caused by overexpression of this enzyme.

  4. MEF2C (show MEF2C Antibodies) is necessary for Mmp13 (show MMP13 Antibodies) gene expression at the transcriptional level and participates in PTH (show PTH Antibodies)-stimulated Mmp13 (show MMP13 Antibodies) gene expression by increased binding to c-FOS at the AP-1 (show JUN Antibodies) site in the Mmp13 (show MMP13 Antibodies) promoter.

  5. data reveal a novel involvement of MMP-13 (show MMP13 Antibodies) in regulating dendritic cell (DC) immunobiology through moderating MHC-I surface presentation, endocytosis and cytokine/chemokine (show CCL1 Antibodies) secretion; furthermore, the reduced MHC-I surface presentation by DCs resulted in a poor CD8 (show CD8A Antibodies)(+) T-cell response in vitro; MMP-13 (show MMP13 Antibodies) might be a promising target for therapeutic intervention in inflammatory diseases

  6. The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (show DDR2 Antibodies)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (show DDR2 Antibodies) and matrix metalloproteinase 13 (show MMP13 Antibodies).

  7. Postnatal chondrocyte-specific deletion of Hdac3 (show HDAC3 Antibodies) with an inducible Col2a1 (show COL2A1 Antibodies)-Cre caused premature production of pErk1/2 and Mmp13 (show MMP13 Antibodies) in the growth plate.

  8. Mmp13 (show MMP13 Antibodies) is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (show PTH Antibodies), and Osterix (show SP7 Antibodies) through distal enhancers.

  9. Our study contributes to the understanding of the role of HIF1alpha (show HIF1A Antibodies) in OA and highlights the HIF1alpha (show HIF1A Antibodies)-beta-catenin (show CTNNB1 Antibodies) interaction, thus providing new insights into the impact of hypoxia in articular cartilage.

  10. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1/protease-activated receptor-1 (show F2R Antibodies) axis may play a role in neurogenesis following physiological and/or pathological stimuli.

Cow (Bovine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. BoHV-4 infection affects various pathways related to cell proliferation and cell surface integrity, at least three of which were centered on upregulation of matrix metalloproteinase 1 (MMP1). MMP1 transcription was upregulated by the BoHV-4 transactivator IE2/RTA (show RBM9 Antibodies), leading to abnormally high metalloproteinase tissue levels, potentially leading to defective endometrium healing and unresolved inflammation.

  2. The expression patterns of MMP1, MMP2 (show MMP2 Antibodies), and MMP8 (show MMP8 Antibodies) were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1, MMP2 (show MMP2 Antibodies), and MMP8 (show MMP8 Antibodies) expression levels with meat quality traits were analyzed in cattle. The expression of MMP1, MMP2 (show MMP2 Antibodies), and MMP8 (show MMP8 Antibodies) were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.

  3. Data suggest that luteolytic factors (such as interferon gamma (show IFNG Antibodies), tumor necrosis factor alpha (show TNF Antibodies), and PGF2a) control expression of MMP1, other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  4. The results showed that a decrease in MMP-1 and MMP-2 (show MMP2 Antibodies) gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.

  5. Cytoskeletal tension modulates MMP-1 gene expression from tenocytes on micropillar substrates.

  6. MMP-1 promotes VEGFR2 (show KDR Antibodies) expression and proliferation of endothelial cells through stimulation of PAR-1 (show F2R Antibodies) and activation of NF-kappaB (show NFKB1 Antibodies)

  7. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  8. the differential expression and localization of membrane-type 1 matrix metalloproteinase (show MMP14 Antibodies) in the corpus luteum suggest that it may have multiple functions throughout the course of the estrous cycle,including activation of pro-MMP-2 (show MMP2 Antibodies)

  9. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 and MMP-13 (show MMP13 Antibodies) (follicular apex (show APEX1 Antibodies) vs. base) for the preovulatory collagenolysis required for follicle rupture

  10. identification of MT1-MMP (show MMP14 Antibodies) in odontoclasts during deciduous tooth resorption might be relevant to the migration activity that these cells have to gain access to the root surface

Rabbit Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. These results suggest that PEP-1-SIRT2 (show SIRT2 Antibodies) promotes matrix metalloproteinases-induced dedifferentiation via ERK (show MAPK1 Antibodies) signaling in articular chondrocytes. .

  2. Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 and decreased TIMP-3 (show TIMP3 Antibodies) secretion.

Horse (Equine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. ANXA2 (show ANXA2 Antibodies) and MMP1 might participate in remodeling during wound healing in the horse.

  2. The polymorphism in the promoter of the MMP-1 gene could be a risk factor for early implant failure of total hip arthroplasty.

  3. These results suggest that MMP-1 and IL-8 (show IL8 Antibodies) are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.

Xenopus laevis Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

MMP1 Antigen Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MMP1

  • matrix metallopeptidase 1 (MMP1) antibody
  • Matrix metalloproteinase 1 (Mmp1) antibody
  • matrix metalloproteinase 1 (RB11133) antibody
  • matrix metalloproteinase 1 (Mmp1) antibody
  • matrix metallopeptidase 13 (Mmp13) antibody
  • matrix metallopeptidase 1 (interstitial collagenase) (MMP1) antibody
  • matrix metallopeptidase 1 S homeolog (mmp1.S) antibody
  • interstitial collagenase (LOC100727966) antibody
  • matrix metallopeptidase 1 (Mmp1) antibody
  • CG4859 antibody
  • Clg antibody
  • Clgn antibody
  • col4 antibody
  • dm1-MMP antibody
  • Dmel\\CG4859 antibody
  • dmmp1 antibody
  • l(2)k04809 antibody
  • MMP-1 antibody
  • MMP-13 antibody
  • Mmp1 antibody
  • Mmp 1 antibody
  • Mmp1a antibody
  • mmp18 antibody

Protein level used designations for MMP1

fibroblast collagenase , interstitial collagenase , matrix metalloprotease 1 , matrix metalloproteinase 1 , MMP-1 , matrix metalloproteinase 1 (type I collagenase) , matrix metalloproteinase-1 , CG4859-PC , CG4859-PD , CG4859-PE , CG4859-PF , CG4859-PG , CG4859-PH , CG4859-PI , CG4859-PJ , CG4859-PK , CG4859-PL , Mmp1-PC , Mmp1-PD , Mmp1-PE , Mmp1-PF , Mmp1-PG , Mmp1-PH , Mmp1-PI , Mmp1-PJ , Mmp1-PK , Mmp1-PL , Collagenase-3 , collagenase 3 , collagenase-1 , matrix metalloproteinase 13 , matrix metalloproteinase-13 , MMP-18 , collagenase-4 , matrix metalloproteinase-18 , xCol4 , matrix metallopeptidase 1a , matrix metalloproteinase 1a (interstitial collagenase) , myocardial collagenase

4312 Homo sapiens
397320 Sus scrofa
37949 Drosophila melanogaster
1790862 Rhodopirellula baltica SH 1
100144547 Bombyx mori
17386 Mus musculus
281308 Bos taurus
100009110 Oryctolagus cuniculus
489428 Canis lupus familiaris
100033896 Equus caballus
495287 Xenopus laevis
101120355 Ovis aries
100727966 Cavia porcellus
300339 Rattus norvegicus
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