anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Antibodies

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping MMP1 Kits (130) and MMP1 Proteins (55) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MMP1 4312 P03956
MMP1 300339  
MMP1    
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Top anti-MMP1 Antibodies at antibodies-online.com

Showing 10 out of 320 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Horse Rabbit Un-conjugated IHC, WB WB Suggested Anti-MMP1 Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate Sample Type: Equine Cartilage ExplantsPrimary Dilution: 1:800Secondary Antibody: Bio-Rad 170-5046 Secondary Dilution: 1:100,000Image Submitted By: Adam WilliamsUniversity of Nottingham 100 μL Log in to see 2 to 3 Days
$249.00
Details
Human Mouse HRP EIA, IHC (fro), IHC (p), WB   1 mL Log in to see 6 to 8 Days
$511.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-MMP1 Antibody Titration:  2.5ug/ml  Positive Control:  HT1080 cell lysate MMP1 is supported by BioGPS gene expression data to be expressed in HT1080 Sample Type: Human Macrophange CellsGreen: primaryRed: phallodinBlue: DAPIYellow: green/redPrimary Dilution: 1:200Secondary Antibody: anti-Rabbit IgG-FITCSecondary Dilution: 1:1000Image Submitted By: Milan FialaUniversity of California, Los Angeles 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image MMP1 antibody detects MMP1 protein at secreted on human endometrial carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human endometrial carcinoma. MMP1 antibody , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of MMP1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MMP1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated ELISA, FACS, ICC, IHC, WB Red: Control Antigen (100ng);Purple: Antigen (10ng);Green: Antigen (50ng);Blue: Antigen (100ng); Dilution: 1/10000 Figure 1: Western blot analysis using MMP1 mAb against HEK293 (1) and MMP1(AA: 24-213)-hIgGFc transfected HEK293 (2) cell lysate.  Dilution: 1/500 - 1/2000 100 μL Log in to see 8 to 11 Days
$577.50
Details
Human Mouse Un-conjugated ELISA, FACS, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: MMP-1 Antibody (6A5) [NBP2-22123] - Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues (left) and human kidney cancer tissues (right) using MMP1 mouse mAb with DAB staining. Western Blot: MMP-1 Antibody (6A5) [NBP2-22123] - Western blot analysis using MMP1 mAb against HEK293 (1) and MMP1(AA: 24-213)-hIgGFc transfected HEK293 (2) cell lysate. 0.1 mL Log in to see 7 to 9 Days
$516.98
Details
Human Mouse Un-conjugated ELISA, FACS, IF, IHC, WB 100 μL Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from A549 cells, treated with etoposide 25uM 24h, using MMP1 (Cleaved-Phe100) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

Top referenced anti-MMP1 Antibodies

  1. Human Polyclonal MMP1 Primary Antibody for WB - ABIN3043405 : Man, Gao, Zhang, Liu, Yan, Huang, Liu: Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma. in Cancer biology & therapy 2011 (PubMed)
    Show all 13 Pubmed References

  2. Polyclonal MMP1 Primary Antibody for IHC (p), IP - ABIN541021 : Metzger, Negm, Plentz, Weismüller, Wedemeyer, Karlsen, Dakna, Mullen, Mischak, Manns, Lankisch: Urine proteomic analysis differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders. in Gut 2012 (PubMed)
    Show all 6 Pubmed References

  3. Mouse (Murine) Polyclonal MMP1 Primary Antibody for IF (p), IHC (p) - ABIN668931 : Luo, Zhang, Wang, Hu, Song, Zhang: The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model. in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2014 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal MMP1 Primary Antibody for FACS, IF - ABIN966588 : Genevay, Finckh, Mezin, Tessitore, Guerne: Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation. in Arthritis research & therapy 2010 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal MMP1 Primary Antibody for IF (p), IHC (p) - ABIN668466 : Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage. in Cells, tissues, organs 2012 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal MMP1 Primary Antibody for ICC, FACS - ABIN969287 : Guan, Shu, Fu, Liu, Xu, Wu: Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells. in FEMS microbiology letters 2009 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal MMP1 Primary Antibody for FACS - ABIN4896251 : Domeij, Modéer, Quezada, Yucel-Lindberg: Cell expression of MMP-1 and TIMP-1 in co-cultures of human gingival fibroblasts and monocytes: the involvement of ICAM-1. in Biochemical and biophysical research communications 2005 (PubMed)

  8. Human Monoclonal MMP1 Primary Antibody for IHC (p), WB - ABIN2475718 : Murray, Duncan, Arbuckle, Melvin, Fothergill: Matrix metalloproteinases and their inhibitors in gastric cancer. in Gut 1999 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal MMP1 Primary Antibody for ICC - ABIN1883181 : Yamakawa, Uchida, Matthay, Makita: Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells. in American journal of physiology. Lung cellular and molecular physiology 2011 (PubMed)

  10. Human Monoclonal MMP1 Primary Antibody for ELISA, FACS - ABIN4334919 : Kim, Park, Kim, Koh, Yoon, Cho, Park: Periostin in Mature Stage Localized Scleroderma. in Annals of dermatology 2017 (PubMed)

More Antibodies against MMP1 Interaction Partners

Human Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. For MMP-1(-1607) 1G/2G, a significant association was observed using the recessive genetic model. In the subgroup studies, a significant association was observed in the Asian subgroup (OR = 1.68; for the recessive model; and OR = 1.59; for the allelic contrast model) and in the European subgroup (OR = 0.65; for the allelic contrast model).

  2. rs1799750 in MMP1 might be a risk factor for rheumatic heart disease in a Han population in Southern China, and individuals carrying the 2G/2G genotype are likely more susceptible to rheumatic heart disease.

  3. RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-kappaB Signaling and MMP1 Expression.

  4. Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer.

  5. Data suggest that matrix metalloproteinase-1 and neutrophil elastase may be important but heretofore unrecognized players in stimulating uterine contractions at the time of labor, and they may explain why indomethacin delays, but does not prevent, preterm labor because indomethacin inhibits the prostaglandin component but not the protease component of labor.

  6. the present study demonstrated that scopoletin inhibited MMP1 and proinflammatory cytokine expression by inhibiting p38 MAPK phosphorylation.

  7. Matrix metalloproteinase 1(MMP1), which was downregulated in myelodysplastic syndromes (MDS)-mesenchymal stromal cells (MSCs), was identified as an inhibitory factor of MDS cell proliferation.

  8. study to explore the relationship between 2 polymorphisms (MMP-1-755 T/G [rs498186] and MMP-3 A/C [rs632478]) and disc degeneration; no significant association of the MMP-1 polymorphism with disc degeneration was found

  9. Expression of GSDMC is increased by UV irradiation in human skin keratinocytes. GSDMC induction contributes to the increase of MMP-1 expression specifically via activation of ERK and JNK pathways.

  10. our results suggest that the typical 1G/2G MMP-1 polymorphic site did not play a direct determinant role in breast cancer among Taiwanese women.

  11. The maternal and fetal 1G/1G MMP1 gene polymorphisms may be strong genetic markers of preeclampsia, occurring either individually or together.

  12. The current study indicated that MMP1 has a key role in the regulation of cervical tumor growth and lymph node metastasis via epithelial mesenchymal transition to a certain extent

  13. 2G allele of MMP-1, C allele of MMP-2 and 5A/6A genotype of MMP-3 are associated with susceptibility and disease progression of type 2 diabetic nephropathy

  14. this study provides insights into the development of a possible alternative therapy manipulating MMP-1 and the mTOR signaling pathway in Epidermal growth factor receptor-tyrosine kinase inhibitor-resistant lung adenocarcinoma.

  15. Specific silencing that targeted AMPK resulted in the enhancement of mobility and contractility and in the production of MMP-1 and MMP-2.

  16. MMP-1 genotype may accelerate the development of HIV-associated neurocognitive disorder (HAND) whereas MMP3 -1612 5A5A genotype may reduce the risk of pathogenesis of HAND.

  17. Authors observed a significant increase in the immunoexpression of collagen I and III in patients with DCM and a significant reduction in the immunoexpression of MMP-1 compared with the control group. Also, the collagen I and TIMP-1 expression indicated a positive linear correlation and respectively a negative linear relationship with collagen III and MMP-1.

  18. findings suggest that the polymorphic genotypes at MMP-1 promoter -1607 may play a major role in determining personal cancer susceptibility for prostate cancer in Taiwan

  19. No significant association was found between MMP-1 (-16071G/2G, -519A/G) variants and obesity.

  20. Reduced expression of types I and III collagen and TIMP-1 as well as the increased expression of MMP-1 and MMP-8 in the anterior vaginal wall tissues play important roles in the onset of pelvic organ prolapse.

Pig (Porcine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. the identification of MMP1 and MMP10 genes in swine is reported.

  2. increased interstitial MMP1 activity during ischemia and reperfusion is a result of the endothelin protein kinase c pathway and may be due to enhanced phosphorylation of mmp1

  3. Results indicate that leukemia inhibitory factor (LIF) and Oncostatin M increase the expression of MMP-1, MMP-3, and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF antagonist MH35-BD.

Fruit Fly (Drosophila melanogaster) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. there are only two MMP genes in Drosophila, DmMmp1 and DmMmp2, which makes Drosophila an attractive system to analyze the basis of MMP specificity. Previously, Drosophila MMPs have been categorized by their pericellular localization, as Mmp1 appeared to be secreted and Mmp2 appeared to be membrane-anchored, suggesting that protein localization was the critical distinction in this small MMP family

  2. results suggest that Ubx regulates organ shape by controlling Mmp1 expression, and the extent and timing of extracellular matrix degradation.

  3. This work identifies Draper-dependent activation of MMP-1 as a novel cascade required for proper glial clearance of severed axons.

  4. Mmp1 negatively regulates ectopic eye differentiation by restricting the rate of proliferation and the levels of expression of retinal-determining genes dachshund and eyes absent.

  5. Data indicate that matrix metalloproteinases mmp1 and mmp2 mutants have distinct heart phenotypes.

  6. These data demonstrate that Mmp1 modulates PDF processing, which leads to daily structural remodeling and circadian behavior.

  7. A primary function of Mmp1, under the control of the JNK pathway, is to promote basement membrane repair, which in turn may permit cell migration and the restoration of a continuous tissue.

  8. Drosophila Mmp1 is involved in the regulation of ISC proliferation for maintenance of gut homeostasis

  9. Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development.

  10. MMP activity is essential for embryonic motor axon fasciculation

  11. Study identified three genes, regeneration (rgn), augmenter of liver regeneration (alr) and Matrix metalloproteinase-1 (Mmp1) expressed specifically in blastema cells during disc regeneration.

Cow (Bovine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. BoHV-4 infection affects various pathways related to cell proliferation and cell surface integrity, at least three of which were centered on upregulation of matrix metalloproteinase 1 (MMP1). MMP1 transcription was upregulated by the BoHV-4 transactivator IE2/RTA, leading to abnormally high metalloproteinase tissue levels, potentially leading to defective endometrium healing and unresolved inflammation.

  2. The expression patterns of MMP1, MMP2, and MMP8 were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1, MMP2, and MMP8 expression levels with meat quality traits were analyzed in cattle. The expression of MMP1, MMP2, and MMP8 were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.

  3. Data suggest that luteolytic factors (such as interferon gamma, tumor necrosis factor alpha, and PGF2a) control expression of MMP1, other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  4. The results showed that a decrease in MMP-1 and MMP-2 gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.

  5. Cytoskeletal tension modulates MMP-1 gene expression from tenocytes on micropillar substrates.

  6. MMP-1 promotes VEGFR2 expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB

  7. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  8. the differential expression and localization of membrane-type 1 matrix metalloproteinase in the corpus luteum suggest that it may have multiple functions throughout the course of the estrous cycle,including activation of pro-MMP-2

  9. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 and MMP-13 (follicular apex vs. base) for the preovulatory collagenolysis required for follicle rupture

  10. identification of MT1-MMP in odontoclasts during deciduous tooth resorption might be relevant to the migration activity that these cells have to gain access to the root surface

  11. MT1-MMP has a role in signaling events mediating EGFR transactivation

  12. IL-4 and IL-13 affect airway smooth muscle (SM) gel contraction via a phosphatidylinositol 3-kinase mediated endogenous production of MMP-1 that alters the interaction between SM cells and collagen fibers.

  13. In cervix, MMP1 is only active during the final cervical ripening process at parturition.

Rabbit Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. These results suggest that PEP-1-SIRT2 promotes matrix metalloproteinases-induced dedifferentiation via ERK signaling in articular chondrocytes. .

  2. the total content and active forms of matrix metalloproteinases (MMPs)-1, -3, and -13 was measured to assess the potential role of the mechanical environment in regulation of matrix turnover by ligament fibroblasts.

  3. Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 and decreased TIMP-3 secretion.

Horse (Equine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. ANXA2 and MMP1 might participate in remodeling during wound healing in the horse.

  2. The polymorphism in the promoter of the MMP-1 gene could be a risk factor for early implant failure of total hip arthroplasty.

  3. These results suggest that MMP-1 and IL-8 are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.

Xenopus laevis Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. matrix metalloproteinases 7, 9, and 18 are required in vivo for macrophage migration during embryonic development

MMP1 Antigen Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MMP1

  • matrix metallopeptidase 1 (MMP1) antibody
  • Matrix metalloproteinase 1 (Mmp1) antibody
  • matrix metalloproteinase 1 (RB11133) antibody
  • matrix metalloproteinase 1 (Mmp1) antibody
  • matrix metallopeptidase 1 (interstitial collagenase) (MMP1) antibody
  • matrix metallopeptidase 1 S homeolog (mmp1.S) antibody
  • interstitial collagenase (LOC100727966) antibody
  • matrix metallopeptidase 1 (Mmp1) antibody
  • CG4859 antibody
  • CLG antibody
  • Clgn antibody
  • col4 antibody
  • dm1-MMP antibody
  • Dmel\\CG4859 antibody
  • dmmp1 antibody
  • l(2)k04809 antibody
  • MMP-1 antibody
  • Mmp1 antibody
  • Mmp 1 antibody
  • Mmp1a antibody
  • mmp18 antibody

Protein level used designations for MMP1

fibroblast collagenase , interstitial collagenase , matrix metalloprotease 1 , matrix metalloproteinase 1 , MMP-1 , matrix metalloproteinase 1 (type I collagenase) , matrix metalloproteinase-1 , CG4859-PC , CG4859-PD , CG4859-PE , CG4859-PF , CG4859-PG , CG4859-PH , CG4859-PI , CG4859-PJ , CG4859-PK , CG4859-PL , Mmp1-PC , Mmp1-PD , Mmp1-PE , Mmp1-PF , Mmp1-PG , Mmp1-PH , Mmp1-PI , Mmp1-PJ , Mmp1-PK , Mmp1-PL , collagenase-1 , MMP-18 , collagenase-4 , matrix metalloproteinase-18 , xCol4 , matrix metallopeptidase 1a , matrix metalloproteinase 1a (interstitial collagenase) , myocardial collagenase

GENE ID SPECIES
4312 Homo sapiens
397320 Sus scrofa
37949 Drosophila melanogaster
1790862 Rhodopirellula baltica SH 1
100144547 Bombyx mori
281308 Bos taurus
100009110 Oryctolagus cuniculus
489428 Canis lupus familiaris
100033896 Equus caballus
495287 Xenopus laevis
101120355 Ovis aries
100727966 Cavia porcellus
300339 Rattus norvegicus
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