MMP1 antibody (AA 20-280)

Catalog No. ABIN3021680

Cited in 2+ publications. The Rabbit Polyclonal anti-MMP1 antibody (ABIN3021680) specifically detects MMP1 in WB. The antibody is reactive with Human samples.

Quick Overview for MMP1 antibody (AA 20-280) (ABIN3021680)

Target: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMP1 Antibody

Binding Specificity: AA 20-280

Sequence: FPATLETQEQ DVDLVQKYLE KYYNLKNDGR QVEKRRNSGP VVEKLKQMQE FFGLKVTGKP DAETLKVMKQ PRCGVPDVAQ FVLTEGNPRW EQTHLTYRIE NYTPDLPRAD VDHAIEKAFQ LWSNVTPLTF TKVSEGQADI MISFVRGDHR DNSPFDGPGG NLAHAFQPGP GIGGDAHFDE DERWTNNFRE YNLHRVAAHE LGHSLGLSHS TDIGALMYPS YTFSGDVQLA QDDIDGIQAI YGRSQNPVQP IGPQTPKACD S

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human MMP1 (NP_002412.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-MMP1 antibody (ABIN3021680)

Wang, Hu, Zhou, Xiong, Zhang, Shehada, Hu, Song, Chen: "Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling." in: Scientific reports, Vol. 7, Issue 1, pp. 13321, (2017) (PubMed).

Yu, Ding, Zhu, Qu, Zhang, Liu, Chen: "IL-22 mediates the oral mucosal wound healing via STAT3 in keratinocytes." in: Archives of oral biology, Vol. 72, pp. 14-20, (2017) (PubMed).

Target Details for MMP1

Target: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Alternative Name: MMP1

Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,MMP1,CLG,CLGN,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP1

Molecular Weight: 54 kDa

Gene ID: 4312

UniProt: P03956