anti-Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) Antibodies

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping MMP11 Kits (47) and MMP11 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MMP11 4320 P24347
MMP11 17385 Q02853
MMP11 25481 Q499S5
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Top anti-MMP11 Antibodies at antibodies-online.com

Showing 10 out of 140 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB MMP11 was detected in paraffin-embedded sections of human appendicitis tissues using rabbit anti- MMP11 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). MMP11 was detected in paraffin-embedded sections of mouse spleen tissues using rabbit anti- MMP11 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 2 to 3 Days
$245.00
Details
Dog Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of MMP11 staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MMP11 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from A549 cells, using MMP-11 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MMP-11 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunofluorescence analysis of A549 cells, using MMP-11 Antibody. The picture on the right is treated with the synthesized peptide. Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 11 to 13 Days
$582.67
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Human MCF7 Cells. 100 μg Log in to see 15 to 18 Days
$324.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-MMP11 Antibody (C-term)(ABIN390135) in 293 cell line lysates (35 µg/lane). MMP11(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p), WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7 to 9 Days
$484.00
Details
Human Mouse Un-conjugated IHC (p), IP, WB 50 μL Log in to see 6 to 8 Days
$390.50
Details

More Antibodies against MMP11 Interaction Partners

Human Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) interaction partners

  1. We believe that genetic variations in the MMP-11 gene may help to predict early-stage Hepatocellular carcinoma and act as reliable biomarkers for Hepatocellular carcinoma progression

  2. In this study, matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI (show MSI1 Antibodies)) has been used for the first time to investigate the distribution of MMP-11 in human breast cancer tissues in order to show a possible correlation between cancerous and healthy samples, by differential proteomics and using such differences for possible cancer diagnosis and/or prognosis.

  3. Authors evaluated the expression of known targets of miR (show MLXIP Antibodies)-125a and found that sirtuin-7 (show SIRT7 Antibodies), matrix metalloproteinase-11, and c-Raf (show RAF1 Antibodies) were up-regulated in tumor tissue by 2.2-, 3-, and 1.7-fold, respectively. Overall, these data support a tumor suppressor role for miR (show MLXIP Antibodies)-125a.

  4. Results revealed that MMP-11 high expression in oral squamous cell carcinoma (OSCC) samples can predict the progression, especially lymph node metastasis, and the survival of OSCC patients.

  5. A new prognostic model for HR-/HER2 (show ERBB2 Antibodies)+ breast cancer based on the expression of MMP11 and CD2 (show CD2 Antibodies) was developed and the distant metastasis-free survival for patients in the high-risk group according to our model was significantly lower than that for those in the low-risk group.

  6. HMGA1 (show HMGA1 Antibodies) and MMP-11 may play a key role in the proliferation and progression of skin tumors in humans.

  7. These results demonstrated that miR (show MLXIP Antibodies)-145 has an inhibitory role in TNBC malignancy by targeting MMP11 and Rab27a (show RAB27A Antibodies), which might be potential therapeutic and diagnostic targets for TNBC.

  8. the data demonstrate that miR125a5p functions as a tumor suppressor gene and serves an important role in inhibiting osteosarcoma cell migration, invasion and EMT (show ITK Antibodies) by targeting MMP11.

  9. MMP-11 overexpression is associated with aggressive tumor phenotype and unfavorable clinical outcome in urothelial carcinomas.

  10. Our study established that high serum levels of MMP-11 are associated with poor clinical outcome and may serve as a prognostic biomarker in colon cancer patients.

Mouse (Murine) Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) interaction partners

  1. Strikingly, MMP11 overexpression protects against type 2 diabetes while Mmp11-/- mice exhibit hallmarks of metabolic syndrome.

  2. Results show that MMP-11 has a paracrine function during mammary gland development that might be harnessed to promote tumor progression, exposing a new link between development and malignancy.

  3. point-out the paradoxical role of MMP11 in favoring the onset and growth of lung metastases but limiting lung foci number, and inhibiting the cancer cell dissemination to other organs

  4. investigation of a potential role of MMP-11 in adipose tissue development

  5. The increased levels of ST-3 in the thymus may be due to the presence of macrophages responsible for clearance of apoptotic cells

  6. downregulated by deglycosylation of CD147 in hepatocarcinoma cells

  7. These data together provide compelling evidence into the function of MMP-11 and suggest that MMP-11 act as a tumor lymphatic metastasis-associated gene.

  8. These findings reveal that the tumor biological marker CD147 functionally mediates MMP-11, VEGF-A (show VEGFA Antibodies) expression and tumor lymphatic metastasis.

  9. Mmp11 exhibits collagenolytic function against collagen VI under normal conditions.

  10. Our study describes the identification of MMP11 as a novel broadly expressed tumor associated antigen as target candidate for cancer immunotherapy.

Xenopus laevis Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) interaction partners

  1. Transgenic tadpoles were prepared with an elastase promoter driving either the ST3 gene or the constitutively active form of Notch (show NOTCH1 Antibodies) (IC).

  2. analysis of substrate specificity for stromelysin-3: alpha1-PI is unlikely to be a physiological substrate

  3. ST3 regulates cell fate and tissue morphogenesis through direct or indirect extracellular matrix remodeling

  4. Laminin receptor precursor cleavage by ST3 plays a role in both physiological and pathological processes.

  5. thyroid hormone (show PTH Antibodies) regulation of Xenopus laevis Stromelysin-3 is mediated by a DNA element in the first intron

  6. Mutational analysis of the cleavage of the cancer-associated laminin receptor by stromelysin-3 reveals the contribution of flanking sequences to site recognition and cleavage efficiency.

  7. ST3 expression, in the absence of T3 hormone, caused significant muscle cell death in the tail of premetamorphic transgenic tadpoles

MMP11 Antigen Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

Gene names and symbols associated with MMP11

  • matrix metallopeptidase 11 (MMP11) antibody
  • matrix metallopeptidase 11 (Mmp11) antibody
  • matrix metallopeptidase 11 L homeolog (mmp11.L) antibody
  • stromelysin-3 (LOC103694874) antibody
  • MMP-11 antibody
  • SL-3 antibody
  • ST3 antibody
  • Stmy3 antibody

Protein level used designations for MMP11

MMP-11 , stromelysin III , stromelysin-3 , SL-3 , matrix metalloproteinase 11 , matrix metalloproteinase-11 , stromelysin 3 , Matrix metalloproteinase 11 (stromelysin 3) , ST3 , gene 14 , Matrix metalloproteinase-11

GENE ID SPECIES
4320 Homo sapiens
17385 Mus musculus
100101604 Oryctolagus cuniculus
25481 Rattus norvegicus
486408 Canis lupus familiaris
100153503 Sus scrofa
539109 Bos taurus
100713229 Cavia porcellus
379501 Xenopus laevis
103694874 Rattus norvegicus
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