Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) ELISA Kits

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping Matrix Metallopeptidase 13 (Collagenase 3) Antibodies (290) and Matrix Metallopeptidase 13 (Collagenase 3) Proteins (41) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MMP13 4322 P45452
MMP13 17386 P33435
MMP13 171052  
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Top Matrix Metallopeptidase 13 (Collagenase 3) ELISA Kits at antibodies-online.com

Showing 10 out of 144 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.113 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 13 to 16 Days
$530.53
Details
Mouse 28 pg/mL 78-5000 pg/mL 96 Tests Log in to see 13 to 16 Days
$545.68
Details
Rat 0.063 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$576.00
Details
Rabbit 23.44 pg/mL 93.75-6000 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,026.67
Details
Chicken 0.63 ng/mL 1.56-100 ng/mL 96 Tests Log in to see 15 to 17 Days
$891.06
Details
Pig 0.113 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 15 to 17 Days
$968.71
Details
Cow 33 pg/mL 78.125-5000 pg/mL 96 Tests Log in to see 15 to 17 Days
$968.71
Details
Horse 6.9 pg/mL 15.625-1000 pg/mL 96 Tests Log in to see 15 to 17 Days
$988.12
Details
Goat 1.25 ng/mL 3.125-200 ng/mL 96 Tests Log in to see 15 to 17 Days
$988.12
Details
Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced Matrix Metallopeptidase 13 (Collagenase 3) ELISA Kits

  1. Mouse (Murine) MMP13 ELISA Kit for Sandwich ELISA - ABIN415612 : Campo, Avenoso, Nastasi, Micali, Prestipino, Vaccaro, DAscola, Calatroni, Campo: Hyaluronan reduces inflammation in experimental arthritis by modulating TLR-2 and TLR-4 cartilage expression. in Biochimica et biophysica acta 2011 (PubMed)
    Show all 10 Pubmed References

  2. ABIN1882517 : Bai, Merchant: A role for CITED2, a CBP/p300 interacting protein, in colon cancer cell invasion. in FEBS letters 2007 (PubMed)
    Show all 7 Pubmed References

  3. Human MMP13 ELISA Kit for Sandwich ELISA - ABIN921071 : Yang, Gao, Rao, Shen: Clinicopathological significance and prognostic value of MMP-13 expression in colorectal cancer. in Scandinavian journal of clinical and laboratory investigation 2012 (PubMed)
    Show all 9 Pubmed References

  4. Mouse (Murine) MMP13 ELISA Kit - ABIN455834 : Campo, Avenoso, DAscola, Scuruchi, Prestipino, Calatroni, Campo: Hyaluronan in part mediates IL-1beta-induced inflammation in mouse chondrocytes by up-regulating CD44 receptors. in Gene 2012 (PubMed)
    Show all 5 Pubmed References

  5. Human MMP13 ELISA Kit for Sandwich ELISA - ABIN414818 : Mern, Fontana, Beierfuß, Thomé, Hegewald et al.: A combinatorial relative mass value evaluation of endogenous bioactive proteins in three-dimensional cultured nucleus pulposus cells of herniated intervertebral discs: identification of potential ... in PLoS ONE 2013 (PubMed)
    Show all 4 Pubmed References

  6. ABIN1882516 : Bedi, Fox, Kovacevic, Deng, Warren, Rodeo: Doxycycline-mediated inhibition of matrix metalloproteinases improves healing after rotator cuff repair. in The American journal of sports medicine 2010 (PubMed)
    Show all 4 Pubmed References

  7. Human MMP13 ELISA Kit for Sandwich ELISA - ABIN625055 : Toegel, Wu, Otero, Goldring, Leelapornpisid, Chiari, Kolb, Unger, Windhager, Viernstein: Caesalpinia sappan extract inhibits IL1?-mediated overexpression of matrix metalloproteinases in human chondrocytes. in Genes & nutrition 2012 (PubMed)
    Show all 4 Pubmed References

  8. Human MMP13 ELISA Kit for Sandwich ELISA - ABIN818166 : Duncan, Smith, Fleming, Partridge, Shimizu, Moran, Cooper: The Histone-Deacetylase-Inhibitor Suberoylanilide Hydroxamic Acid Promotes Dental Pulp Repair Mechanisms Through Modulation of Matrix Metalloproteinase-13 Activity. in Journal of cellular physiology 2015 (PubMed)
    Show all 3 Pubmed References

  9. Rat (Rattus) MMP13 ELISA Kit for Sandwich ELISA - ABIN365611 : Zheng, Zhong, Qin, Chen, Wu, Zeng, Ye, Li, Yuan, Yao, Chen: Advanced oxidation protein products induce inflammatory response in fibroblast-like synoviocytes through NADPH oxidase -dependent activation of NF-κB. in Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2013 (PubMed)
    Show all 3 Pubmed References

  10. Rabbit MMP13 ELISA Kit for Sandwich ELISA - ABIN416019 : Mével, Merceron, Vinatier, Krisa, Richard, Masson, Lesoeur, Hivernaud, Gauthier, Abadie, Nourissat, Houard, Wittrant, Urban, Beck, Guicheux: Olive and grape seed extract prevents post-traumatic osteoarthritis damages and exhibits in vitro anti IL-1β activities before and after oral consumption. in Scientific reports 2016 (PubMed)
    Show all 2 Pubmed References

More ELISA Kits for Matrix Metallopeptidase 13 (Collagenase 3) Interaction Partners

Zebrafish Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. MeHg impairs tail development at least partially by activation of the tissue remodeling proteases Mmp9 (show MMP9 ELISA Kits) and Mmp13.

  2. Zebra fish embryogenesis requires MMP-13 and dexamethasone and hydrocortisone modulate the expression of this gene, leading to increased activity and potentially contributing to subsequent dysmorphogenesis.

  3. JNK (show MAPK8 ELISA Kits)-Mmp13 signaling pathway plays an essential role in regulating the innate immune cell migration in response to severe injury in vivo

Xenopus laevis Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. XCL3 and XCL4 can be differentially induced by prolactin (show PRL ELISA Kits) and thyroid hormone (show PTH ELISA Kits)(3)

Mouse (Murine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. data reveal a novel involvement of MMP-13 in regulating dendritic cell (DC) immunobiology through moderating MHC-I surface presentation, endocytosis and cytokine/chemokine (show CCL1 ELISA Kits) secretion; furthermore, the reduced MHC-I surface presentation by DCs resulted in a poor CD8 (show CD8A ELISA Kits)(+) T-cell response in vitro; MMP-13 might be a promising target for therapeutic intervention in inflammatory diseases

  2. The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (show DDR2 ELISA Kits)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (show DDR2 ELISA Kits) and matrix metalloproteinase 13.

  3. Postnatal chondrocyte-specific deletion of Hdac3 (show HDAC3 ELISA Kits) with an inducible Col2a1 (show COL2A1 ELISA Kits)-Cre caused premature production of pErk1/2 and Mmp13 in the growth plate.

  4. Mmp13 is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (show PTH ELISA Kits), and Osterix (show SP7 ELISA Kits) through distal enhancers.

  5. Our study contributes to the understanding of the role of HIF1alpha (show HIF1A ELISA Kits) in OA and highlights the HIF1alpha (show HIF1A ELISA Kits)-beta-catenin (show CTNNB1 ELISA Kits) interaction, thus providing new insights into the impact of hypoxia in articular cartilage.

  6. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (show MMP1 ELISA Kits)/protease-activated receptor-1 (show F2R ELISA Kits) axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  7. IL-1Ra (show IL1RN ELISA Kits) is associated with MMP-13 expression and has a novel function in such regulation without interference of the IL-1 (show IL1A ELISA Kits) signaling cascade.

  8. We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 expression and activity.

  9. B-16 melanoma cells with up-regulated MMP-13 expression promoted invasion of tumor cells through Matrigel compared with control cells transfected with empty vector. Knocked-down MMP-13 expression also decreased invading cell numbers.

  10. MMP-12 (show MMP12 ELISA Kits) and MMP-13 alter strain K infection in mice and play a role in inflammatory regulation by modulating cytokine levels.

Human Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. IL-6 (show IL6 ELISA Kits)-stimulated MMP-13 expression was independent of IL-1beta (show IL1B ELISA Kits) stimulation and was blocked by SAHA, suggesting that SAHA inhibits IL-6 (show IL6 ELISA Kits) signaling in Osteoarthritis (OA) chondrocytes.

  2. High MMP13 expression is associated with intervertebral disc degeneration.

  3. data demonstrate that MMP-13 is critical for the development of osteolytic lesions in Multiple myeloma and that targeting the MMP-13 protein - rather than its catalytic activity - constitutes a potential approach to mitigating bone disease in affected patients.

  4. Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritic chondrocytes, which manifested in increased expression of ADAMTS5 (show ADAMTS5 ELISA Kits), MMP13, and decreased COL2A1 (show COL2A1 ELISA Kits) expression.

  5. Matrix metalloprotease (MMP) regulation was the top pathway involved in gingival aging. MMP3 (show MMP3 ELISA Kits), MMP9 (show MMP9 ELISA Kits), MMP12 (show MMP12 ELISA Kits), and MMP13 were upregulated in old gingival tissues, concomitantly with interleukin-1 beta (IL1B (show IL1B ELISA Kits)) expression.

  6. these findings support roles for both cFOS (indirect) and ATF3 (show ATF3 ELISA Kits) (direct) in effecting MMP13 transcription in human chondrocytes.

  7. Oxytocin prevents cartilage matrix destruction via regulating MMP1 (show MMP1 ELISA Kits) and MMP13.

  8. These studies have uncovered a new, ATP6V1H (show ATP6V1H ELISA Kits)-mediated pathway that regulates bone formation, and defines a new mechanism of disease that leads to bone loss. We propose that MMP9 (show MMP9 ELISA Kits)/MMP13 could be therapeutic targets for patients with this rare genetic disease.

  9. To conclude, Pseudomonas aeruginosa infection induced the expression of matrix metalloproteinases, and Pseudomonas aeruginosa type III secretion system appeared to be a key player in MMP-12 (show MMP12 ELISA Kits) and MMP-13 expression, which is further controlled by NF-kappaB (show NFKB1 ELISA Kits) signaling.

  10. In osteoarthritis (OA) chondrocytes, hydrostatic pressure (HP) restores the expression levels of some miRNAs, downregulates MMP-13, ADAMTS-5 (show ADAMTS5 ELISA Kits), and HDAC-4 (show HDAC4 ELISA Kits), and modulates the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway activation.

Horse (Equine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. The DNA microarray analysis for matrix metalloproteinase (MMP)-related mRNA expression in equine superficial digital flexor tendinitis indicated that mRNA level of MMP-13 was apparently up-regulated in the tendinitis as compared to normal tendon.

Cow (Bovine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. p38 (show MAPK14 ELISA Kits) phosphorylation and MMP13 expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage.

  2. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  3. MMP-13 treatment of fresh articular cartilage results in cleaved fibromodulin (show FMOD ELISA Kits) fragments

  4. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 (show MMP1 ELISA Kits) and MMP-13 (follicular apex (show APEX1 ELISA Kits) vs. base) for the preovulatory collagenolysis required for follicle rupture

  5. involvement of p38 MAP kinase (show MAPK14 ELISA Kits) in the hyaluronan oligosaccharide induction of MMP-13

  6. MMP-13 and collagenase have roles in chondrocyte hypertrophy induced by type II collagen (show COL2A1 ELISA Kits)

  7. At high but naturally occurring concentrations the collagen peptide CB12 (show PABPC4 ELISA Kits)-II induced an increase in the expressions of MMP-13 and cleavage of type II collagen (show COL2A1 ELISA Kits) by collagenase in the mid zone and also in the superficial zone.

Rabbit Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. These results suggest that PEP-1-SIRT2 (show SIRT2 ELISA Kits) promotes matrix metalloproteinases-induced dedifferentiation via ERK (show MAPK1 ELISA Kits) signaling in articular chondrocytes.

  2. chitosan-pDNA nanoparticles encoding shRNA targeting MMP-3 (show MMP3 ELISA Kits) and -13 had great potential in silencing the dedifferentiation-related genes for regenerating prolonged and endurable cartilage.

  3. Leptin (show LEP ELISA Kits) can induce MMP-13 and have a synergistic induction effect on NO with TNF-alpha (show TNF ELISA Kits) in rabbit articular chondrocytes in vitro.

Pig (Porcine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. TNF-alpha (show TNF ELISA Kits) induced MMP-13 expression by condylar cells might be involved in the degradation of the juvenile condyle.

Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) Antigen Profile

Antigen Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene names and symbols associated with MMP13

  • matrix metallopeptidase 13 (MMP13) antibody
  • matrix metallopeptidase 13 (Mmp13) antibody
  • matrix metalloproteinase 7 (MGC68994) antibody
  • matrix metallopeptidase 13a (mmp13a) antibody
  • matrix metallopeptidase 13 (collagenase 3) like S homeolog (mmp13l.S) antibody
  • matrix metallopeptidase 13 (collagenase 3) (mmp13) antibody
  • matrix metalloproteinase 13 (LOC100136348) antibody
  • matrix metallopeptidase 12 (MMP12) antibody
  • matrix metalloproteinase 13 (mmp13) antibody
  • matrix metallopeptidase 13 (mmp13) antibody
  • matrix metallopeptidase 13 (collagenase 3) like L homeolog (mmp13l.L) antibody
  • cb1034 antibody
  • Clg antibody
  • CLG3 antibody
  • gene A antibody
  • MANDP1 antibody
  • MGC108008 antibody
  • MMP-13 antibody
  • Mmp1 antibody
  • MMP13 antibody
  • xcl3 antibody
  • xCol antibody

Protein level used designations for MMP13

MMP-13 , collagenase 3 , matrix metalloproteinase 13 (collagenase 3) , Collagenase-3 , collagenase-1 , interstitial collagenase , matrix metalloproteinase 13 , matrix metalloproteinase-13 , UMRCASE , collagenase-3 , MMPLg , MMPLh , gene 11 , matrix metallopeptidase 13 (collagenase 3) , gene A , collagenase 3-like

GENE ID SPECIES
4322 Homo sapiens
17386 Mus musculus
171052 Rattus norvegicus
281914 Bos taurus
379552 Xenopus laevis
387293 Danio rerio
398056 Xenopus laevis
443113 Ovis aries
451513 Pan troglodytes
493679 Felis catus
613098 Xenopus (Silurana) tropicalis
703980 Macaca mulatta
100008685 Oryctolagus cuniculus
100009711 Equus caballus
100012553 Monodelphis domestica
100136348 Salmo salar
100396943 Callithrix jacchus
100462632 Pongo abelii
100526826 Ictalurus punctatus
100552256 Anolis carolinensis
100584961 Nomascus leucogenys
397346 Sus scrofa
397823 Xenopus laevis
395683 Gallus gallus
403763 Canis lupus familiaris
100731756 Cavia porcellus
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