anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) Antibodies

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping MMP8 Kits (106) and MMP8 Proteins (23) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MMP8 17394 O70138
MMP8 63849 O88766
MMP8 4317 P22894
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Top anti-MMP8 Antibodies at antibodies-online.com

Showing 10 out of 183 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated IHC (p), ELISA, WB Anti- MMP8 Picoband antibody,IHC(P) IHC(P): Mouse Spleen Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Observed bind size: 60KD Anti- MMP8 Picoband antibody,IHC(P) IHC(P): Human Appendicitis Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-MMP8 Pab (ABIN390153) in mouse liver tissue lysate (35 µg/lane). MMP8 (arrow) was detected using the purified polyclonal antibody Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human stomach carcinoma labeled with Rabbit Anti-MMP-8 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$318.45
Details
Human Mouse Un-conjugated CyTOF, FACS, IHC MMP-8 in Human Breast Cancer Tissue. MMP-8 was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using 8 ug/mL Mouse Anti-Human MMP-8 Monoclonal Antibody  composing glandular lobules. 500 μg Log in to see 8 to 9 Days
$387.55
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using MMP-8 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MMP-8 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IP, IHC, WB   100 μg Log in to see 2 to 3 Days
$265.00
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 4 to 6 Days
$240.00
Details

MMP8 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-MMP8 Antibodies

  1. Human Polyclonal MMP8 Primary Antibody for IF (p), IHC (p) - ABIN736283 : Zhang, Li, Zhang, Fu, Cui: Hydrogen sulfide suppresses the expression of MMP-8, MMP-13, and TIMP-1 in left ventricles of rats with cardiac volume overload. in Acta pharmacologica Sinica 2013 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal MMP8 Primary Antibody for CyTOF, FACS - ABIN4899598 : Arechavaleta-Velasco, Marciano, Díaz-Cueto, Parry: Matrix metalloproteinase-8 is expressed in human chorion during labor. in American journal of obstetrics and gynecology 2004 (PubMed)

  3. Human Polyclonal MMP8 Primary Antibody for IHC, IHC (p) - ABIN4335077 : Ong, Elkington, Brilha, Ugarte-Gil, Tome-Esteban, Tezera, Pabisiak, Moores, Sathyamoorthy, Patel, Gilman, Porter, Friedland: Neutrophil-Derived MMP-8 Drives AMPK-Dependent Matrix Destruction in Human Pulmonary Tuberculosis. in PLoS pathogens 2015 (PubMed)

  4. Human Polyclonal MMP8 Primary Antibody for IP, IHC - ABIN223233 : Ikonomidis, Jones, Barbour, Stroud, Clark, Kaplan, Zeeshan, Bavaria, Gorman, Spinale, Gorman: Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with bicuspid or tricuspid aortic valves. in The Journal of thoracic and cardiovascular surgery 2007 (PubMed)

More Antibodies against MMP8 Interaction Partners

Mouse (Murine) Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) interaction partners

  1. MMP8 plays an important role in intestinal I/R injury through mechanisms involving increased inflammation and loss of claudin-3 (show CLDN3 Antibodies)

  2. These results suggest that some of the anti-inflammatory effects of Dexamethasone are mediated through increased MMP-8 expression.

  3. These results suggest a novel pathogenetic role of MMP8 and implicate modulation of its activity as a tractable strategy for therapies against cerebral ischemia.

  4. Fusion peptide inhibitors of MMP-8/-9 prevent endotoxic shock if administered within a strict time window.

  5. the loss of MMP-8 likely has pleiotropic effects on innate immunity and angiogenesis that are reflected in changes in the protease web.

  6. A previously unknown role of MMP8 in M2-macrophage polarization by cleaving fibromodulin (show FMOD Antibodies) and therefore increasing the bioavailability of TGF-beta (show TGFB1 Antibodies).

  7. MMP-8-deficient mice had significantly lower serum triglyceride (TG) levels (P = 0.003) and larger HDL (show HSD11B1 Antibodies) particles compared with wild-type (WT) mice. However, no differences were observed in the apoA-I (show APOA1 Antibodies) levels.

  8. These results demonstrate that MMP-8 critically mediates microglial activation by modulating TNF-alpha (show TNF Antibodies) activity, which may explain neuroinflammation in septic mouse brain.

  9. MMP-13 (show MMP13 Antibodies) prevails over MMP-8 in collagen degradation in atheromata.

  10. MMP8 enhances vascular smooth muscle cell proliferation via an ADAM10 (show ADAM10 Antibodies), N-cadherin (show CDH2 Antibodies), and beta-catenin (show CTNNB1 Antibodies)-mediated pathway and plays an important role in neointima formation.

Human Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) interaction partners

  1. Data show that individuals with MMP-8 -799TT genotype and intermediate HIV disease stage are at higher risk for the advancement of HIV disease. MMP-8 polymorphism indicated a trend of elevated risk for the modulation of HIV-associated neurocognitive disorder (HAND) severity. MMP-8 -799TT genotype may facilitate the risk for the development of HAND with tobacco and alcohol usage.

  2. The serum levels of IL-8 (show IL8 Antibodies), MIP-1 alpha (show CCL3 Antibodies), MIP-1 beta (show CCL4 Antibodies), MMP-8, Resistin (show RETN Antibodies), FLRG (show FSTL3 Antibodies), and BCAM (show BCAT2 Antibodies) were significantly higher in breast cancer patients, but LAP and TSH-beta (show TSHB Antibodies) levels were lower.

  3. Matrix metalloproteinase-1 (show MMP1 Antibodies), -8, -9 and the risk of cardiovascular complications in patients with CHD (show CHDH Antibodies) before and after myocardial revascularization.

  4. Our study provides evidence for the tumour-suppressive mechanisms of MMP-8 in OTSCC by interplay with TGF-b1 and VEGF-C (show VEGFC Antibodies).

  5. These results provide the first evidence that MMP8 SNP at the rs11225394 locus is associated with the increased risk of osteonecrosis of the femoral head in Chinese Han population.

  6. Low MMP-8/TIMP-1 (show TIMP1 Antibodies) reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 (show TIMP1 Antibodies) may help to differentiate it from acute coronary syndrome

  7. Plasma levels of MMP-1 (show MMP1 Antibodies), MMP-8, and MMP-9 (show MMP9 Antibodies) are associated with COPD (show ARCN1 Antibodies) severity and can be used as a biomarker to better understand the characteristics of COPD (show ARCN1 Antibodies) patients.

  8. there is a negative correlation between blood MMP8 and HDL (show HSD11B1 Antibodies)-cholesterol levels, suggesting a contributory role of MMP8 in metabolic alterations in acne inversa

  9. plasma concentrations of MMP-7 (show MMP7 Antibodies), MMP-8, -9 and TIMP-1 (show TIMP1 Antibodies) within 96 h from the onset of acute pancreatitis symptoms are elevated in acute pancreatitis patients compared with healthy controls

  10. MMP-8 is a vital component of the myoepithelial tumour-suppressor function. It restores MEC (show CCL28 Antibodies) interaction with the matrix, opposes TGF-beta (show TGFB1 Antibodies) signalling and MMP-9 (show MMP9 Antibodies) proteolysis, which contributes to inhibition of tumour cell invasion.

MMP8 Antigen Profile

Protein Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene names and symbols associated with MMP8

  • matrix metallopeptidase 8 (MMP8) antibody
  • matrix metallopeptidase 8 (Mmp8) antibody
  • neutrophil collagenase (LOC100339790) antibody
  • BB138268 antibody
  • CLG1 antibody
  • HNC antibody
  • MMP-8 antibody
  • MMP8 antibody
  • PMNL-CL antibody

Protein level used designations for MMP8

matrix metallopeptidase 8 (neutrophil collagenase) , matrix metalloproteinase 8 , MMP-8 , collagenase 2 , collagenase-2 , matrix metalloproteinase-8 , neutrophil collagenase , neutrophil collagenease , PMNL collagenase , matrix metalloproteinase 8 (neutrophil collagenase)

GENE ID SPECIES
740516 Pan troglodytes
17394 Mus musculus
63849 Rattus norvegicus
4317 Homo sapiens
100724670 Cavia porcellus
100339790 Oryctolagus cuniculus
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