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anti-Megakaryocyte-Associated tyrosine Kinase (MATK) Antibodies

The protein encoded by MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack. Additionally we are shipping Megakaryocyte-Associated tyrosine Kinase Proteins (10) and Megakaryocyte-Associated tyrosine Kinase Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MATK 4145 P42679
MATK 17179 P41242
MATK 60450 P41243
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Top anti-Megakaryocyte-Associated tyrosine Kinase Antibodies at antibodies-online.com

Showing 10 out of 117 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$537.17
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB Western blot analysis of extracts from Jurkat cells, using MATK antibody. ABIN6275839 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated FACS, ELISA, WB Figure 1: Flow cytometric analysis of K562 cells using MATK mouse mAb (green) and negative control (purple) . Figure 2: Western blot analysis using MATK mouse mAb against K562 cell lysate (1) . 100 μL 3 to 4 Days
$393.80
Details
Human Mouse Un-conjugated ELISA, FACS 100 μL 11 to 14 Days
$522.50
Details
Human Rabbit Un-conjugated WB Antibody is used in Western blot to detect CHK in mouse heart tissue lysate. 400 μL 2 to 3 Days
$515.63
Details
Mouse Rabbit Un-conjugated IHC (p), WB Western blot analysis in mouse spleen tissue lysates (35ug/lane). Mouse Matk Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL Available
$363.46
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using MATK antibody (ABIN5974003) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat kidney using MATK antibody (ABIN5974003) at dilution of 1/100 (40x lens). 100 μL 11 to 16 Days
$426.40
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (35.2 KDa) . 200 μL 11 to 12 Days
$440.00
Details

Top referenced anti-Megakaryocyte-Associated tyrosine Kinase Antibodies

  1. Human Polyclonal MATK Primary Antibody for IHC (p), ELISA - ABIN544390 : Zrihan-Licht, Lim, Keydar, Sliwkowski, Groopman, Avraham: Association of csk-homologous kinase (CHK) (formerly MATK) with HER-2/ErbB-2 in breast cancer cells. in The Journal of biological chemistry 1997 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal MATK Primary Antibody for FACS, ELISA - ABIN969495 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Megakaryocyte-Associated tyrosine Kinase Interaction Partners

Human Megakaryocyte-Associated tyrosine Kinase (MATK) interaction partners

  1. After IGF-I stimulation, CTK is recruited to IGF-IR and its recruitment facilitates CTK's subsequent association with phospho-SHPS-1.

  2. ERBB2 binds to the SH2 domain of CHK and inhibits cell growth in human breast tumor cell lines

  3. Overexpression of the Csk homologous kinase facilitates phosphorylation of akt/protein kinase b in breast neoplasms

  4. CHK Leu223 stabilizes the movement of the alphaC-helix of the protein tyrosine kinase

  5. Loss of CHK expression is associated with human brain tumors

  6. Nuclear multi-lobulation in late S phase, which is dependent on polymerization and depolymerization of microtubules, may be involved in nuclear Chk-induced inhibition of proliferation.

  7. striking functional differences between the Csk and Chk SH2 domains and revealed functional similarities between the Chk and Src SH2 domains

  8. This study describes for the first time the Src-independent actions of CHK and provides novel insights into CHK function in neural cells.

  9. Matk/CHK is not functionally redundant with Csk, and this tyrosine kinase plays an important role as a regulator of immunologic responses

  10. Findings indicate that the importance of the N-terminal domain to Chk-induced tyrosine phosphorylation in the nucleus, and implicate that nuclear tyrosine-phosphorylated proteins may contribute to inhibition of cell proliferation.

  11. Progesterone increases MATK in mast cells and reducs cell proliferation.

  12. These results reveal a potentially important role for CHK in Src activation and tumorigenicity in colon cancer cells.

  13. CHK is capable of inhibiting the CXCL12-CXCR4 pathway in neuroblastoma.

Mouse (Murine) Megakaryocyte-Associated tyrosine Kinase (MATK) interaction partners

  1. Matk plays a critical role in bone metabolism by impairing the functions of osteoclasts and osteoblasts via distinct mechanisms involving inhibition of c-Src-dependent and -independent signaling pathways.

Cow (Bovine) Megakaryocyte-Associated tyrosine Kinase (MATK) interaction partners

  1. After IGF-I stimulation, CTK is recruited to IGF-IR and its recruitment facilitates CTK's subsequent association with phospho-SHPS-1.

Megakaryocyte-Associated tyrosine Kinase (MATK) Antigen Profile

Protein Summary

The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Gene names and symbols associated with MATK

  • megakaryocyte-associated tyrosine kinase (matk) antibody
  • megakaryocyte-associated tyrosine kinase (MATK) antibody
  • megakaryocyte-associated tyrosine kinase (Matk) antibody
  • zinc finger RNA binding protein 2 (ZFR2) antibody
  • Batk antibody
  • CHK antibody
  • CTK antibody
  • HHYLTK antibody
  • HYL antibody
  • HYLTK antibody
  • Lsk antibody
  • Ntk antibody
  • si:ch211-63j24.2 antibody

Protein level used designations for MATK

megakaryocyte-associated tyrosine kinase , megakaryocyte-associated tyrosine-protein kinase-like , CSK homologous kinase , Csk-homologous kinase , Csk-type protein tyrosine kinase , HYL tyrosine kinase , hematopoietic consensus tyrosine-lacking kinase , hydroxyaryl-protein kinase , leukocyte carboxyl-terminal src kinase related , megakaryocyte-associated tyrosine-protein kinase , protein kinase HYL , tyrosine kinase MATK , tyrosine-protein kinase CTK , tyrosylprotein kinase , Csk homologous kinase , protein kinase NTK , megakaryocyte-associated tyrosine kinase (non-receptor protein tyrosine kinase) , non-receptor protein kinase protein , protein kinase BATK , carboxyl-terminal SRC kinase homologous kinase

GENE ID SPECIES
567405 Danio rerio
769076 Gallus gallus
100477232 Ailuropoda melanoleuca
4145 Homo sapiens
17179 Mus musculus
60450 Rattus norvegicus
611999 Canis lupus familiaris
100521543 Sus scrofa
504668 Bos taurus
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