MATK antibody (N-Term)

Catalog No. ABIN359988

Product Details anti-MATK Antibody

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MATK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes MATK.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MATK.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MATK

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Alternative Name: MATK (MATK Products)

Synonyms: si:ch211-63j24.2 antibody, CHK antibody, CTK antibody, HHYLTK antibody, HYL antibody, HYLTK antibody, Lsk antibody, Ntk antibody, Batk antibody, megakaryocyte-associated tyrosine kinase antibody, zinc finger RNA binding protein 2 antibody, matk antibody, MATK antibody, Matk antibody, ZFR2 antibody

Background: MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.Synonyms: CHK, CTK, HYL, HYLTK, Hematopoietic consensus tyrosine-lacking kinase, Megakaryocyte-associated tyrosine-protein kinase

Gene ID: 4145, 9606

UniProt: P42679