Meiosis Specific with OB Domains Proteins (MEIOB)

May be involved in early meiosis (By similarity).. Additionally we are shipping MEIOB Antibodies (6) and many more products for this protein.

Gene Name	GeneID	UniProt
MEIOB	254528	Q8N635
MEIOB	685099	B0BMX9
MEIOB	75178	Q9D513

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Top MEIOB Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No.	Origin	Source	Conjugate	Quantity	Supplier	Delivery	Price	Details
ABIN3129089	Insect Cells	Mouse	His tag	1 mg	Log in to see	60 Days	$9,626.73	Details
ABIN3083539	Insect Cells	Human	His tag	1 mg	Log in to see	60 Days	$9,626.73	Details
ABIN1594033	Yeast	Rat	His tag	1 mg	Log in to see	60 to 71 Days	$3,325.67	Details

MEIOB interacts with RPA and SPATA22.
we propose that RPA and this new single-strand DNA binding protein MEIOB, are essential to ensure the proper stabilization of recombinases which is required for successful homology search and meiotic recombination.

MEIOB and SPATA22 form an obligate complex and contain defined interaction domains. A single residue D383 in MEIOB is indispensable for the MEIOB-SPATA22 interaction. The MEIOB/SPATA22 complex interacts with the RPA heterotrimeric complex in a collaborative manner.
MEIOB is a meiosis-specific paralogue of RPA1. MEIOB colocalizes with RPA in foci on meiotic chromosomes. MEIOB binds to single-stranded DNA and exhibits 3'-5' exonuclease activity. MEIOB forms a complex with RPA and with SPATA22. Chromatin localization and stability of MEIOB depends on SPATA22 and vice versa. MEIOB is essential for meiotic recombination in both sexes.

May be involved in early meiosis (By similarity).

meiosis-specific with OB domain-containing protein , protein expressed in male leptotene and zygotene spermatocytes 675

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