Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
May be involved in early meiosis (By similarity).. Additionally we are shipping MEIOB Antibodies (6) and many more products for this protein.
Showing 3 out of 3 products:
MEIOB interacts with RPA and SPATA22.
we propose that RPA and this new single-strand DNA binding protein MEIOB, are essential to ensure the proper stabilization of recombinases which is required for successful homology search and meiotic recombination.
MEIOB and SPATA22 form an obligate complex and contain defined interaction domains. A single residue D383 in MEIOB is indispensable for the MEIOB-SPATA22 interaction. The MEIOB/SPATA22 complex interacts with the RPA heterotrimeric complex in a collaborative manner.
MEIOB is a meiosis-specific paralogue of RPA1. MEIOB colocalizes with RPA in foci on meiotic chromosomes. MEIOB binds to single-stranded DNA and exhibits 3'-5' exonuclease activity. MEIOB forms a complex with RPA and with SPATA22. Chromatin localization and stability of MEIOB depends on SPATA22 and vice versa. MEIOB is essential for meiotic recombination in both sexes.
May be involved in early meiosis (By similarity).
meiosis-specific with OB domain-containing protein
, protein expressed in male leptotene and zygotene spermatocytes 675