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MS4A8 encodes a member of the membrane-spanning 4A gene family.
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MS4A8B is a novel differentiation marker of the intestinal epithelium that supports the maintenance of a physiological barrier function in the gut (show GUSB Antibodies) by modulating the transcriptome and by conferring an increased resistance to reactive oxygen species.
This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.3, among a cluster of family members.
four-span transmembrane protein 4
, membrane-spanning 4-domains subfamily A member 8
, membrane-spanning 4-domains, subfamily A, member 8B