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Merlin Antibodies

(Neurofibromin 2 (NF2))
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development\; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008].
Merlin antibody  (AA 477-576) Merlin antibody  (AA 477-576) Merlin antibody (AA 477-576) (ABIN6144548)

NF2 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated

Merlin antibody  (AA 30-239) Merlin antibody  (AA 30-239) Merlin antibody (AA 30-239) (ABIN7434395)

NF2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

Merlin antibody  (AA 30-311) Merlin antibody  (AA 30-311) Merlin antibody (AA 30-311) (ABIN7441928)

NF2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

Merlin Antibodies by Grade

Find Merlin Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Merlin Antibodies by Reactivity

Find Merlin Antibodies for a variety of species such as anti-Human Merlin, anti-Rat Merlin, anti-Mouse Merlin. The species listed below are among those available. Click on a link to go to the corresponding products.

Merlin Antibodies by Application

Find Merlin Antibodies validated for a specific application such as WB, ELISA, IF (p), IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

Merlin Antibodies by Host

Find Merlin Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

Merlin Antibodies by Binding Specificity

Find Merlin Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Merlin Antibodies by Clonality

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Merlin Antibodies by Clone

Find Merlin Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

Merlin Antibodies by Conjugate

Find Merlin Antibodies with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Merlin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (6)
Cat. No. ABIN6144548
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7434395
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7441928
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7159413
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6256364
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7138643
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN390756
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (4)
  • (2)
Cat. No. ABIN104130
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
  • (2)
Cat. No. ABIN1532019
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN2789402
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN1327740
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6263224
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN6144550
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7260429
Quantity 200 μL
Datasheet Datasheet
Reactivity Chicken, Human, Mouse, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7299378
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Merlin Antibodies

Hu, Du, Shelton, Oldham, DiPersio, Klein: "An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice." in: Cell stem cell, Vol. 21, Issue 1, pp. 91-106.e6, (2018) (PubMed).

Vasilyeva, Murzina, Kireev, Pivovarov: "Influence of Membrane Receptor Lateral Diffusion on the Short-Term Depression of Acetylcholine-Induced Current in Helix Neurons." in: Cellular and molecular neurobiology, (2017) (PubMed).

Chen, Zhang, Xie, Wang, Cai, Choi, David, Huang, Yabuta, Nojima, Anders, Pan: "Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP." in: Genes & development, Vol. 29, Issue 12, pp. 1285-97, (2015) (PubMed).

Lavado, He, Paré, Neale, Olson, Giovannini, Cao: "Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators." in: Development (Cambridge, England), Vol. 140, Issue 16, pp. 3323-34, (2013) (PubMed).

Yu, Zeidel, Hill: "Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast." in: PLoS ONE, Vol. 7, Issue 11, pp. e48897, (2012) (PubMed).

Angelo, Wu, Meng, Sun, Kopetz, McCutcheon, Slopis, Kurzrock: "Combining Curcumin (Diferuloylmethane) and Heat Shock Protein Inhibition for Neurofibromatosis 2 Treatment: Analysis of Response and Resistance Pathways." in: Molecular cancer therapeutics, (2011) (PubMed).

Zhang, Bai, David, Dong, Zheng, Cai, Giovannini, Liu, Anders, Pan: "The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals." in: Developmental cell, Vol. 19, Issue 1, pp. 27-38, (2010) (PubMed).

Lallemand, Saint-Amaux, Giovannini: "Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells." in: Journal of cell science, Vol. 122, Issue Pt 22, pp. 4141-9, (2010) (PubMed).

Wang, Lu, Tang, Wang, Wu: "The phosphorylation status of merlin in sporadic vestibular Schwannomas." in: Molecular and cellular biochemistry, Vol. 324, Issue 1-2, pp. 201-6, (2009) (PubMed).

Yang, Hinds: "Phosphorylation of ezrin by cyclin-dependent kinase 5 induces the release of Rho GDP dissociation inhibitor to inhibit Rac1 activity in senescent cells." in: Cancer research, Vol. 66, Issue 5, pp. 2708-15, (2006) (PubMed).

Aliases for Merlin Antibodies

neurofibromin 2 (NF2) Antibodies
neurofibromin 2 (Nf2) Antibodies
neurofibromin 2a (merlin) (nf2a) Antibodies
neurofibromin 2b (merlin) (nf2b) Antibodies
neurofibromin 2 (merlin) S homeolog (nf2.S) Antibodies
ACN Antibodies
BANF Antibodies
merlin Antibodies
NF2 Antibodies
nf2 Antibodies
NF2a Antibodies
SCH Antibodies
zgc:194620 Antibodies
zgc:194631 Antibodies
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