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The protein encoded by MBD1 is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). Additionally we are shipping MBD1 Kits (5) and MBD1 Proteins (4) and many more products for this protein.
Showing 10 out of 102 products:
Human Monoclonal MBD1 Primary Antibody for ChIP, IP - ABIN252496
Reese, Bachman, Baylin, Rountree: The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1. in Molecular and cellular biology 2003
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Human Polyclonal MBD1 Primary Antibody for IF, WB - ABIN517757
Staples, Myers, Beveridge, Patil, Lee, Swanton, Howell, Boulton, Collis: The centriolar satellite protein Cep131 is important for genome stability. in Journal of cell science 2012
Show all 2 Pubmed References
Cow (Bovine) Polyclonal MBD1 Primary Antibody for WB - ABIN2779420
Villa, Morey, Raker, Buschbeck, Gutierrez, De Santis, Corsaro, Varas, Bossi, Minucci, Pelicci, Di Croce: The methyl-CpG binding protein MBD1 is required for PML-RARalpha function. in Proceedings of the National Academy of Sciences of the United States of America 2006
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Human Polyclonal MBD1 Primary Antibody for WB - ABIN1882100
Hendrich, Bird: Identification and characterization of a family of mammalian methyl-CpG binding proteins. in Molecular and cellular biology 1998
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Human Monoclonal MBD1 Primary Antibody for ELISA, IHC - ABIN393589
Crowther-Swanepoel, Broderick, Di Bernardo, Dobbins, Torres, Mansouri, Ruiz-Ponte, Enjuanes, Rosenquist, Carracedo, Jurlander, Campo, Juliusson, Montserrat, Smedby, Dyer, Matutes, Dearden, Sunter, Hall, Mainou-Fowler, Jackson, Summerfield, Harris, Pettitt: Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. in Nature genetics 2010
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MBD1 (show DPEP1 Antibodies) may be a tumor suppressor gene in advanced colorectal cancer (CRC (show CALR Antibodies))and affect the development and metastasis of CRC (show CALR Antibodies) by regulating 8 tumor suppressor genes through binding with SP1 (show PSG1 Antibodies).
Our findings imply that reduced stability and enhanced dynamics of MBD1 (show DPEP1 Antibodies) or MBD6 (show MBD6 Antibodies) is the origin of ATP7B (show ATP7B Antibodies) dysfunction in Wilson disease patients with the G85V or G591D mutation.
MBD1 (show DPEP1 Antibodies) regulates localization and activity of Tet1 (show TET1 Antibodies) in a CXXC3 domain-dependent manner.
the binding of MBD1 (show DPEP1 Antibodies) to nucleosomes demonstrates sequence preferences depending on the position of the methyl groups on the nucleosome.
c-myc (show MYC Antibodies) plays a key role in MBD1 (show DPEP1 Antibodies) mediated epigenetic silencing of KEAP1 (show KEAP1 Antibodies).
Molecular dynamic simulation reveals mechanism of the recognition of dimethylated CpG sites by MBD1 (show DPEP1 Antibodies) protein.
MBD1 targets short interspersed nuclear elements, but does not exclude RNA Polymerase III.
This study investigates the genetic association between methyl-CpG-binding domain (MBD (show DPEP1 Antibodies)) gene polymorphisms and schizophrenia.
We demonstrated the importance of Aire's interaction with the ATF7ip (show ATF7IP Antibodies)-MBD1 (show DPEP1 Antibodies) protein complex in maintaining central tolerance
an important function of MBD1 (show DPEP1 Antibodies) in DNA repair and mediation of chemoradioresistance of cancer cells
MBD1 (show DPEP1 Antibodies) has a role in neural stem cell maintenance and epigenetic regulation.
H19 (show NCKAP1 Antibodies) lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1 (show DPEP1 Antibodies).
regulatory loop formed by MBD1 (show DPEP1 Antibodies) and miR (show MLXIP Antibodies)-195 is an important component of the epigenetic network that controls aNSC fate
MBD1 (show DPEP1 Antibodies), miR (show MLXIP Antibodies)-184, and Numbl (show NUMBL Antibodies) form a regulatory network that helps control the balance between proliferation and differentiation of adult neural stem/progenitor cells.
Results indicate that MBD1 (show DPEP1 Antibodies) can interpret the CpG dinucleotide as a repressive signal in vivo regardless of its methylation status.
These data show, for the first time, the involvement of methyl-CpG binding domain proteins in the regulation of the MAGE (show MAGEB10 Antibodies)-A genes.
Mbd1 (show DPEP1 Antibodies)(-/-) mice exhibit several core deficits associated with autism, including reduced social interaction, learning deficits, anxiety, defective sensory motor gating, depression and abnormal brain serotonin activity.
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions\; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides\; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
CXXC-type zinc finger protein 3
, methyl-CpG binding domain protein 1 isoform PCM1
, methyl-CpG-binding domain protein 1
, protein containing methyl-CpG-binding domain 1
, the regulator of fibroblast growth factor 2 (FGF-2) transcription
, methyl-CpG-binding protein MBD1
, coiled-coil domain containing 11