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Mitochondrial Transcription Termination Factor (MTERF) ELISA Kits

MTERF encodes a mitochondrial transcription termination factor. Additionally we are shipping Mitochondrial Transcription Termination Factor Antibodies (51) and Mitochondrial Transcription Termination Factor Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MTERF 85261 Q9EPI8
MTERF 7978 Q99551
MTERF    
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Rat
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More ELISA Kits for Mitochondrial Transcription Termination Factor Interaction Partners

Human Mitochondrial Transcription Termination Factor (MTERF) interaction partners

  1. MTERF1 has the ability to accommodate alternate active conformations.

  2. It has been demonstrated that MTERF1 arrests mitochondrial DNA (mtDNA) replication with distinct polarity whereby MTERF1 acts as a directional contra-helicase, blocking mtDNA unwinding by the mitochondrial helicase TWINKLE.

  3. Studies indicate that the structure of the mitochondrial transcription termination factor (MTERF1) provides insight into the mechanism of binding, recognition of the termination sequence and the conformational changes involved in mediating termination.

  4. Single nucleotide polymorphism in MTERF gene is associated with epithelial ovarian cancer.

  5. data suggested that hMTERF4 is an essential factor for cell proliferation, which is probably modulated by mitochondrial transcription to promote cell proliferation

  6. Data show that mTERF protein levels materially affect the amount of readthrough transcription on the antisense strand of mtDNA, whilst the effects on sense-strand transcripts are complex, and suggest the influence of compensatory mechanisms.

  7. Presented are the crystal structures of human mitochondrial regulator MTERF, a transcription termination factor also implicated in replication pausing, in complex with double-stranded DNA oligonucleotides containing the tRNA(Leu)(UUR) gene sequence.

  8. The structure indicates that upon sequence recognition MTERF1 unwinds the DNA molecule, promoting eversion of three nucleotides.

  9. mTERF mRNA levels were higher in elite athletes compared with moderately active subjects

  10. mTERF exists in mitochondria in two forms, an active monomer and an inactive large size complex

  11. monomeric human mTERF is fully active in its non-phosphorylated form and that the protein does not require additional cellular factors to terminate mitochondrial transcription in vitro

  12. analysis of DNA light-strand preferential recognition of human mitochondria transcription termination factor mTERF

  13. Results indicate a role for mTERF in mtDNA replication, in addition to its role in transcription.

Fruit Fly (Drosophila melanogaster) Mitochondrial Transcription Termination Factor (MTERF) interaction partners

  1. mTerf5 knockdown led to enhanced replication pausing at mTTF binding sites, a decrease in fragile replication intermediates containing single-stranded segments, and the disappearance of species containing segments of RNA/DNA hybrid

  2. The first ever-obtained evidence for an in vivo role of an animal mitochondrial transcription termination factor.

  3. DmTTF might play multiple roles in the mtDNA transcription process, for which different levels of the protein with respect to mtRNApol are required.

Mitochondrial Transcription Termination Factor (MTERF) Antigen Profile

Antigen Summary

This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome\; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding.

Gene names and symbols associated with MTERF

  • mitochondrial transcription termination factor 1 (MTERF1) antibody
  • mitochondrial transcription termination factor (MTERF) antibody
  • mitochondrial transcription termination factor 1 (Mterf1) antibody
  • mitochondrial transcription termination factor 1 (mterf1) antibody
  • mitochondrial transcription termination factor (mTTF) antibody
  • BG:DS01068.4 antibody
  • CG18124 antibody
  • Dmel\\CG18124 antibody
  • DmTTF antibody
  • DS01068.4 antibody
  • Mterf antibody

Protein level used designations for MTERF

mitochondrial transcription termination factor , Transcription termination factor, mitochondrial , mitochondrial transcription termination factor 1 , transcription termination factor, mitochondrial , CG18124-PA , mTTF-PA , transcription termination factor 1, mitochondrial

GENE ID SPECIES
703725 Macaca mulatta
472439 Pan troglodytes
100172789 Pongo abelii
85261 Rattus norvegicus
522191 Bos taurus
549783 Xenopus (Silurana) tropicalis
7978 Homo sapiens
34837 Drosophila melanogaster
100355865 Oryctolagus cuniculus
100716389 Cavia porcellus
100516386 Sus scrofa
100684053 Canis lupus familiaris
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