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Dietary fat absorption from the small intestine is facilitated by acyl-CoA:monoacylglycerol transferase (MOGAT\; EC 22.214.171.124) and acyl-CoA:diacylglycerol acyltransferase (DGAT\; see MIM 604900) activities. Additionally we are shipping MOGAT2 Kits (5) and MOGAT2 Proteins (5) and many more products for this protein.
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Human Polyclonal MOGAT2 Primary Antibody for ELISA, WB - ABIN4335271
Cao, Hawkins, Brozinick, Liu, Zhang, Burn, Shi: A predominant role of acyl-CoA:monoacylglycerol acyltransferase-2 in dietary fat absorption implicated by tissue distribution, subcellular localization, and up-regulation by high fat diet. in The Journal of biological chemistry 2004
MGAT2 (show MGAT2 Antibodies) in the intestine plays an indispensable role in enhancing metabolic efficiency but also raise the possibility that MGAT2 (show MGAT2 Antibodies) in other tissues may contribute to the regulation of energy metabolism.
MGAT2 possessed an intrinsic acyl-CoA:diacylglycerol acyltransferase (DGAT) activity which could provide an alternative pathway for triacylglycerol synthesis in the absence of DGAT
Mogat2 is a key determinant of energy metabolism in response to dietary fat and suggest that inhibition or deletion of this enzyme may prove to be a useful strategy for treating obesity.
the release of gut (show GUSB Antibodies) peptides following oral triglyceride ingestion in MGAT2 (show MGAT2 Antibodies) and DGAT1 (show DGAT1 Antibodies) knock-out mice was investigated.
MGAT (show MGAT2 Antibodies)catalyzes the synthesis of diacylglycerol, a precursor of triacylglycerol. MGAT mediates the absorption of dietary fat by catalyzing the resynthesis of triacylglycerol in enterocytes, a step required for delivering absorbed fat to other tissues.
MGAT2 (show MGAT2 Antibodies) is a monoacylglycerol acyltransferase expressed in the small intestine
MGAT2 (show MGAT2 Antibodies) functions as a dimeric or tetrameric protein and selectively heterodimerizes with DGAT1 (show DGAT1 Antibodies) in mammalian cells
Mogat2(IKO) mice increased energy expenditure although to a lesser degree than Mogat2(-/-) mice and were protected against diet-induced weight gain and associated comorbidities
The described cell-based assay adds a new methodology for the development and evaluation of MGAT2 (show MGAT2 Antibodies) inhibitors for the treatment of obesity and type 2 diabetes
Diacylglycerol acyltransferase-2 (show AWAT1 Antibodies) and monoacylglycerol acyltransferase-2 are ubiquitinated proteins that are degraded by the 26S proteasome (show Psmd4 Antibodies)
The use of 1-oleoyl-glycerol-d5 and (U13)C-TG oil followed by LC/ESI (show PI3 Antibodies)/MS/MS detection of stable-isotopic labeled DAG, TG, or glycerol provides a wide range of applications to study pathophysiological regulation of the monoacylglycerol pathway and MGAT2 (show MGAT2 Antibodies) activity.
MGAT2 (show MGAT2 Antibodies) may play an important role in dietary fat absorption
Dietary fat absorption from the small intestine is facilitated by acyl-CoA:monoacylglycerol transferase (MOGAT\; EC 126.96.36.199) and acyl-CoA:diacylglycerol acyltransferase (DGAT\; see MIM 604900) activities. MOGAT catalyzes the joining of monoacylglycerol and fatty acyl-CoAs to form diacylglycerol (Yen and Farese, 2003
2-acylglycerol O-acyltransferase 2
, acyl CoA:monoacylglycerol acyltransferase 2
, monoacylglycerol O-acyltransferase 2
, putative monoacylglycerol acyltransferase 2
, 2-acylglycerol O-acyltransferase 2-like
, acyl-CoA:monoacylglycerol acyltransferase 2
, diacylglycerol acyltransferase 2-like protein 5
, diacylglycerol O-acyltransferase candidate 5
, 2-acylglycerol O-acyltransferase 2-B
, acyl CoA:monoacylglycerol acyltransferase 2-B
, acyl-CoA:monoacylglycerol acyltransferase 2-B
, monoacylglycerol O-acyltransferase 2-B