MVB12B Proteins

The protein encoded by MVB12B is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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4 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3083487
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3123528
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
ReactivityHuman
Application AA, AP, ELISA, WB
Order details Cat. No. ABIN1353443
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2720746
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
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MVB12B Protein Profile

Protein Summary

The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MVB12B

  • multivesicular body subunit 12B (MVB12B) antibody
  • multivesicular body subunit 12B (Mvb12b) antibody
  • multivesicular body subunit 12B S homeolog (mvb12b.S) antibody
  • multivesicular body subunit 12Ba (mvb12ba) antibody
  • 2610200O14Rik antibody
  • 2610528K11Rik antibody
  • AI414895 antibody
  • C9orf28 antibody
  • fam125b antibody
  • fam125ba antibody
  • mvb12b antibody
  • RGD1309709 antibody
  • zgc:152929 antibody

Protein level used designations for MVB12B

ESCRT-I complex subunit MVB12B , family with sequence similarity 125, member B , multivesicular body subunit 12B , uncharacterized protein LOC432218 , family with sequence similarity 125, member B, duplicate a

GENE ID SPECIES
89853 Homo sapiens
72543 Mus musculus
362118 Rattus norvegicus
100728526 Cavia porcellus
432218 Xenopus laevis
767667 Danio rerio