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MVB12B Products

(Multivesicular Body Subunit 12B (MVB12B))

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The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

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Featured MVB12B Categories

MVB12B Antibodies

High quality antibodies with extensive validation data.

MVB12B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MVB12B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Guinea Pig, Human
Application WB
Validations
Cat. No. ABIN6751612
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN2791520
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
Cat. No. ABIN5938973
Quantity 100 μL
Datasheet Datasheet

Recommended MVB12B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353443
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083487
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3123528
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to MVB12B

multivesicular body subunit 12B (MVB12B), multivesicular body subunit 12B (Mvb12b), multivesicular body subunit 12B S homeolog (mvb12b.S), multivesicular body subunit 12Ba (mvb12ba), 2610200O14Rik, 2610528K11Rik, AI414895, C9orf28, FAM125B, Fam125b, fam125b, fam125ba, mvb12b, RGD1309709, zgc:152929

Protein level used designations for MVB12B

  • ESCRT-I complex subunit MVB12B
  • family with sequence similarity 125, member B
  • multivesicular body subunit 12B
  • uncharacterized protein LOC432218
  • family with sequence similarity 125, member B, duplicate a
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