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Murine Retrovirus Integration Site 1 Homolog (MRVI1) ELISA Kits

MRVI1 is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). Additionally we are shipping Murine Retrovirus Integration Site 1 Homolog Antibodies (5) and Murine Retrovirus Integration Site 1 Homolog Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MRVI1 17540 Q9WUX5
MRVI1 10335 Q9Y6F6
MRVI1 281918 Q9N1F0
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Top Murine Retrovirus Integration Site 1 Homolog ELISA Kits at antibodies-online.com

Showing 3 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Mouse < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details

More ELISA Kits for Murine Retrovirus Integration Site 1 Homolog Interaction Partners

Mouse (Murine) Murine Retrovirus Integration Site 1 Homolog (MRVI1) interaction partners

  1. cGKIbeta signaling via IRAG is essential for regulation of smooth muscle tone and of intracellular calcium by NO and by atrial natriuretic peptide.

  2. conclude that cGMP-dependent relaxation of hormone receptor-triggered smooth muscle contraction essentially depends on the interaction of cGKI-IRAG with IP(3)RI

  3. Reports use of non-AUG (CUG) translation initiation codon in one of the transcript variants of MRVI1 gene in mouse and human.

Human Murine Retrovirus Integration Site 1 Homolog (MRVI1) interaction partners

  1. p.P186S substitution (rs35857561) in MRVI1 that segregated with moyamoya syndrome in both the Italian and German family. rs35857561 polymorphism in MRVI1 may be a genetic susceptibility factor for moyamoya in European patients with neurofibromatosis type 1. MRVI1 is a functional partner of ITPR1, PRKG1 and GUCY1A3, which are involved in response to nitric oxide.

  2. In the present study we analyzed the structure and function of the human IRAG/MRVI1 gene

  3. IRAG is required for PKG1beta-regulated cyclic calcium release during motility of osteoclasts

  4. IRAG appears to be essentially involved in the NO/cGK-dependent inhibition of InsP(3)-dependent Ca(2+)-signaling in colonic smooth muscle

  5. cGMP-dependent protein kinase Ibeta binds to TFII-I and IRAG through a common interaction motif

  6. These findings reveal that interaction between IRAG and InsP3RI has a central role in NO/cGMP-dependent inhibition of platelet aggregation and in vivo thrombosis.

  7. Reports use of non-AUG (CUG) translation initiation codon in one of the transcript variants of MRVI1 gene in mouse and human.

Cow (Bovine) Murine Retrovirus Integration Site 1 Homolog (MRVI1) interaction partners

  1. cGKIbeta signaling via IRAG is essential for regulation of smooth muscle tone and of intracellular calcium by NO and by atrial natriuretic peptide.

  2. cGMP-dependent protein kinase Ibeta binds to TFII-I and IRAG through a common interaction motif

Murine Retrovirus Integration Site 1 Homolog (MRVI1) Antigen Profile

Antigen Summary

This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used.

Gene names and symbols associated with MRVI1

  • MRV integration site 1 (Mrvi1) antibody
  • murine retrovirus integration site 1 homolog (MRVI1) antibody
  • BB115629 antibody
  • IRAG antibody
  • JAW1L antibody
  • Ris1 antibody

Protein level used designations for MRVI1

JAW1-related protein MRVI1 , inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate , inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate , murine retrovirus integration site 1 protein , protein MRVI1 , retroviral integration site 1 , IP3R-associated cGMP kinase substrate , IP3 receptor associated cGMP kinase substrate

GENE ID SPECIES
17540 Mus musculus
10335 Homo sapiens
281918 Bos taurus
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