Murine Retrovirus Integration Site 1 Homolog ELISA Kits
MRVI1 is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV).
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Murine Retrovirus Integration Site 1 Homolog (MRVI1) ELISA Kit ELISA Kit
Murine Retrovirus Integration Site 1 Homolog (MRVI1) ELISA Kit ELISA Kit
Murine Retrovirus Integration Site 1 Homolog (MRVI1) ELISA Kit ELISA Kit
Murine Retrovirus Integration Site 1 Homolog (MRVI1) Antigen Profile
Protein Summary
This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used.
Gene names and symbols associated with MRVI1
- MRV integration site 1 (Mrvi1) antibody
- murine retrovirus integration site 1 homolog (MRVI1) antibody
- BB115629 antibody
- IRAG antibody
- JAW1L antibody
- Ris1 antibody
Protein level used designations for MRVI1
JAW1-related protein MRVI1 , inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate , inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate , murine retrovirus integration site 1 protein , protein MRVI1 , retroviral integration site 1 , IP3R-associated cGMP kinase substrate , IP3 receptor associated cGMP kinase substrate
GENE ID | SPECIES |
---|---|
17540 | Mus musculus |
10335 | Homo sapiens |
281918 | Bos taurus |
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