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MUTED encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1).
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The muted protein is involved in the selective export of CgA (show CGA Antibodies) during the biogenesis of large dense-core vesicle.
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.
BLOC-1 subunit 5
, biogenesis of lysosome-related organelles complex 1 subunit 5
, muted homolog
, protein Muted homolog
, Protein Muted homolog