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Cell surface receptor, which is involved in signal transduction processes. Additionally we are shipping Myelin Protein Zero-Like 1 Proteins (9) and Myelin Protein Zero-Like 1 Kits (4) and many more products for this protein.
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MPZL1 is a target gene within the 1q24.1-24.2 amplicon that plays a pivotal role in HCC (show FAM126A Antibodies) cell migration and tumor metastasis, and a novel MPZL1/Src (show SRC Antibodies)/cortactin (show CTTN Antibodies) signaling cascade.
Clinico-electrophysiological features and MRI (show C7ORF49 Antibodies) findings are described in leg musculature from three patients belonging to a CMT2J (show MPZ Antibodies) pedigree due to MPZ (show MPZ Antibodies) Thr124Met mutation.
PZR is a major receptor of ConA and has an important role in cell signaling via c-Src (show SRC Antibodies). Considering the various biological activities of ConA, the study of PZR may have major therapeutic implications
Characterization of PZR1b, an alternative spliced isoform of PZR.
the MPZL1/PZR gene may be important in the predisposition to schizophrenia among Han Chinese
Phosphorylation and localization of PZR in cultured endothelial cells is reported.
These data reveal a complex role for Mpzl3 (show MPZL3 Antibodies) in the control of skin development, hair growth, and adipose cell functions.
describe the function of the mPZR isoforms in vivo, particularly with respect to their roles in regulating SHP-2-dependent cell migration during development.
SIRPalpha and PZR serve as scaffolds that facilitate plasma membrane recruitment and signaling of NS-associated SHP-2 mutants.
Phosphorylation and localization of PZR in cultufred endothelial cells is reported.
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine- protein kinases. Isoform 3 seems to have a dominant negative role\; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
myelin protein zero-like 1
, myelin protein zero-like protein 1
, immunoglobulin family transmembrane protein
, protein zero related
, protein zero-related
, zero-related protein