Myozenin 2 Proteins (MYOZ2)

The protein encoded by MYOZ2 belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types.

list all proteins Gene Name GeneID UniProt
Mouse MYOZ2 MYOZ2 59006 Q9JJW5
Rat MYOZ2 MYOZ2 295426  
Human MYOZ2 MYOZ2 51778 Q9NPC6
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Top Myozenin 2 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
Details
Escherichia coli (E. coli) Human His tag   50 μg Log in to see 4 Days
$522.50
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Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,684.00
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Insect cells (Sf9) Human GST tag,His tag Validation with Western Blot 20 μg Log in to see 6 to 10 Days
$504.90
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Escherichia coli (E. coli) Human His tag   10 μg Log in to see 15 to 16 Days
$300.00
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Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$582.75
Details

More Proteins for Myozenin 2 (MYOZ2) Interaction Partners

Mouse (Murine) Myozenin 2 (MYOZ2) interaction partners

  1. analysis of post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy

  2. calsarcin-1 negatively modulates the functions of calcineurin.

  3. study defined proximal promoter region of calsarcin-1 (CS-1)& calsarcin-2 (CS-2 (show MYOZ1 Proteins))genes; data suggest NF-kappaB (show NFKB1 Proteins) is required for transcription of CS-1 (show CAT Proteins) gene, but not CS-2 (show MYOZ1 Proteins)

  4. The sarcomeric protein CS1 prevents Ang-II-induced cardiomyocyte hypertrophy at least in part via inhibition of calcineurin signaling.

  5. MYOZ2 mutations are rare causes of familial familial hypertrophic cardiomyopathy.

Human Myozenin 2 (MYOZ2) interaction partners

  1. may play a modifying role in hypertrophic cardiomyopathy by affecting the penetrance or degree of performance of the MYH7 (show MYH7 Proteins) gene

  2. The cardiac phenotype in hypertrophic cardiomyopathy caused by MYOZ2 mutations might be independent of calcineurin activity in the heart.

  3. Mutations in MYOZ1 (show MYOZ1 Proteins) and MYOZ2 are at least very rare events as an underlying disease mechanism for idiopathic or familial DCM

Myozenin 2 (MYOZ2) Protein Profile

Protein Summary

The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.

Gene names and symbols associated with Myozenin 2 Proteins (MYOZ2)

  • myozenin 2 (MYOZ2)
  • myozenin 2 S homeolog (myoz2.S)
  • myozenin 2 L homeolog (myoz2.L)
  • myozenin 2 (myoz2)
  • myozenin 2 (Myoz2)
  • 1110012I24Rik protein
  • C4orf5 protein
  • CMH16 protein
  • CS-1 protein
  • DKFZp468M0519 protein
  • Fatz-2 protein
  • LOC733663 protein
  • MGC52797 protein
  • MYOZ2 protein
  • Myozenin-2 protein
  • Myozl2 protein

Protein level used designations for Myozenin 2 Proteins (MYOZ2)

calsarcin 1 , myozenin 2 , myozenin-2 , FATZ-related protein 2 , calsarcin-1 , myozenin-like 2 , calcineurin-binding protein calsarcin-1 , muscle-specific protein

GENE ID SPECIES
733663 Sus scrofa
380065 Xenopus laevis
422682 Gallus gallus
494787 Xenopus laevis
496895 Xenopus (Silurana) tropicalis
740177 Pan troglodytes
100173530 Pongo abelii
100526817 Ovis aries
59006 Mus musculus
295426 Rattus norvegicus
51778 Homo sapiens
540487 Bos taurus
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