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MYOZ2 Protein (His tag)

Recombinant MYOZ2 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318797
$423.29
Plus shipping costs $50.00
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Quick Overview for MYOZ2 Protein (His tag) (ABIN7318797)

Target

See all MYOZ2 Proteins
MYOZ2 (Myozenin 2 (MYOZ2))

Protein Type

Recombinant

Origin

  • 6
  • 1
  • 1
Human

Source

  • 3
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 90 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This MYOZ2 protein is labelled with His tag.

    Purpose

    Recombinant Human Myozenin-2/MYOZ2 Protein (His Tag)

    Sequence

    Met 1-Leu264

    Characteristics

    Recombinant Human Myozenin-2 is produced by our E.coli expression system and the target gene encoding Met1-Leu264 is expressed with a 6His tag at the C-terminus.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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    Expression System
    Conjugate
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    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 10 mM Tris-HCl, pH 8.0.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    MYOZ2 (Myozenin 2 (MYOZ2))

    Alternative Name

    Myozenin-2/MYOZ2

    Background

    C4orf5,Calsarcin-1,FATZ-Related Protein 2,MYOZ2,Myozenin-2,Myozenin 2 (MYOZ2) is a 264 amino acid protein that belongs to the myozenin family. MYOZ2 binds to Calcineurin, a phosphatase that is involved in calcium-dependent signal transduction in diverse cell types. MYOZ2 is one of the sarcomeric proteins and plays an important role in myofibrillogenesis and the modulation of calcineurin signaling. It may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and plays an important role in the modulation of calcineurin signaling. Defects in MYOZ2 are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16), a hereditary heart disorder.

    Molecular Weight

    Calculated MW: 30.9 kDa

    Observed MW: 38 kDa

    Gene ID

    51778

    UniProt

    Q9NPC6
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