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NAA25 encodes the auxiliary subunit of the heteromeric N-terminal acetyltransferase B complex. Additionally we are shipping N(alpha)-Acetyltransferase 25, NatB Auxiliary Subunit Antibodies (32) and many more products for this protein.
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Mdm20 acts as a novel regulator of Rictor, thereby controlling mTORC2 (show CRTC2 Proteins) activity, and leading to the activation of PKCalphaS657 and FoxO1 (show FOXO1 Proteins).
The human NatB complex composed of Naa20 (NAT3 (show NAT5 Proteins)) and Naa25 (MDM20) N-terminally acetylates Met-Glu (show DCTN1 Proteins)-, Met-Asp (show ASIP Proteins)-, Met-Asn- and Met-Gln- N-termini, and is important for the structure and function of actomyosin fibers and for proper cellular migration.
hMdm20 (C12orf30) is an auxiliary subunit of the human NatB N-terminal acetyltransferase (show NAA15 Proteins) complex while hNat3 (NAT5 (show NAT5 Proteins)) is the catalytic subunit. This ribosome associated complex acetylates nascent Met-Asp (show ASIP Proteins)/Glu (show DCTN1 Proteins)- polypeptides.
There are associations between juvenile idiopathic arthritis and variants in the TNFAIP3 (show TNFAIP3 Proteins), STAT4 (show STAT4 Proteins), and C12orf30 regions that have previously shown associations with other autoimmune diseases, including rheumatoid arthritis and systemic lupus erythematosus.
Mdm20 is highly expressed in the developing mouse brain.
This gene encodes the auxiliary subunit of the heteromeric N-terminal acetyltransferase B complex. This complex acetylates methionine residues that are followed by acidic or asparagine residues.
N-alpha-acetyltransferase 25, NatB auxiliary subunit
, N-terminal acetyltransferase B complex subunit NAA25
, mitochondrial distribution and morphology 20
, natB complex subunit MDM20
, N-terminal acetyltransferase B complex subunit MDM20
, Nalpha acteyltransferase 25
, mitochondrial distribution and morphology protein 20
, liver regeneration-related protein LRRGT00164