anti-Naked Cuticle Homolog 2 (Drosophila) (NKD2) Antibodies

In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.. Additionally we are shipping Naked Cuticle Homolog 2 (Drosophila) Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NKD2 72293 Q8VE28
NKD2 85409 Q969F2
NKD2 308068  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Naked Cuticle Homolog 2 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Horse Rabbit Un-conjugated WB WB Suggested Anti-NKD2 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Western blot analysis in Jurkat cell line lysates (35ug/lane) using NKD2  Antibody (C-term). This demonstrates this antibody detected the NKD2 protein (arrow). Flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram) using NKD2  Antibody (C-term), followed by FITC-conjugated donkey-anti-rabbit secondary antibodies. 0.4 mL 6 to 8 Days
$522.50
Details
Human Goat Un-conjugated ELISA   100 μg 6 to 7 Days
$278.78
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of Phospho-NAKED2(Tyr247) in lysates of Jurkat, using Phospho-NAKED2(Tyr247) Antibody(ABIN6267903). 100 μL 11 to 12 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of NAKED2 in lysates of Jurkat, using NAKED2 Antibody(ABIN6268319). 100 μL 11 to 12 Days
$450.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis in Jurkat cell line lysates (35ug/lane). NKD2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$550.00
Details
Bat Goat Un-conjugated ELISA   100 μg 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of NKD2 transfected lysate using anti-NKD2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with NKD2 MaxPab mouse polyclonal antibody (B01) . Western Blot analysis of NKD2 expression in transfected 293T cell line by NKD2 MaxPab polyclonal antibody.Lane 1: NKD2 transfected lysate(34.30 KDa).Lane 2: Non-transfected lysate. 100 μL 11 to 12 Days
$425.71
Details
Human Mouse Un-conjugated WB Western Blot analysis of NKD2 expression in transfected 293T cell line by NKD2 MaxPab polyclonal antibody.Lane 1: NKD2 transfected lysate(34.21 KDa).Lane 2: Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details

Top referenced anti-Naked Cuticle Homolog 2 (Drosophila) Antibodies

  1. Human Polyclonal NKD2 Primary Antibody for IHC, IHC (p) - ABIN4339837 : Cao, Yang, Jin, Zhang, He, Zhan, Herman, Zhong, Guo: Silencing NKD2 by Promoter Region Hypermethylation Promotes Esophageal Cancer Progression by Activating Wnt Signaling. in Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 (PubMed)

  2. Human Polyclonal NKD2 Primary Antibody for ELISA - ABIN451610 : Zhang, Cagatay, Amanai, Zhang, Kline, Castrillon, Ashfaq, Oz, Wharton: Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2. in Molecular and cellular biology 2007 (PubMed)

More Antibodies against Naked Cuticle Homolog 2 (Drosophila) Interaction Partners

Zebrafish Naked Cuticle Homolog 2 (Drosophila) (NKD2) interaction partners

  1. data indicate that zebrafish Nkd1 and Nkd2 function to limit both canonical and non-canonical Wnt signaling

Mouse (Murine) Naked Cuticle Homolog 2 (Drosophila) (NKD2) interaction partners

  1. studies provide compelling evidence that downregulation of NKD2 expression and alterations in associated regulated pathways have a significant role in driving OS tumor growth and metastasis

  2. Mouse naked cuticle 2 (mNkd2) is a direct transcriptional target of Hoxc8 in vivo.

Human Naked Cuticle Homolog 2 (Drosophila) (NKD2) interaction partners

  1. The experiments in vitro suggested that knockdown of ZFAS1 repressed bladder cancer cell proliferation via up-regulating KLF2 and NKD2 expression, and inhibited cell migration and invasion via down-regulating ZEB1 and ZEB2 expression.

  2. Reduced expression of NKD2 correlated with hyperactivation of the Wnt/beta-catenin pathway and doxorubicin resistance in hepatocellular carcinoma cells

  3. ZFAS1 over-expression confers an oncogenic function in gastric cancer and this function is partly dependent on repressing KLF2 and NKD2

  4. NKD2 is frequently methylated in human esophageal cancer, and the expression of NKD2 is regulated by promoter region methylation. NKD2 suppresses esophageal cancer progression by inhibiting Wnt signaling both in vitro and in vivo.

  5. NKD2 is the key molecular marker to study the progression of osteosarcoma development, and it may be used for better prognosis of the disease in early stage

  6. curcumin significantly inhibited the proliferation of colorectal cancer cells and upregulated the expression of NKD2 in SW620 colorectal cancer cells.

  7. NKD2 regulates osteosarcoma cell proliferation and apoptosis by inhibiting the Wnt signaling.MiR-130b targets NKD2 and regulates the Wnt signaling to promote proliferation and inhibit apoptosis of osteosarcoma cells.

  8. NKD2 is frequently methylated in human breast cancer, and the expression of NKD2 is regulated by promoter region methylation.

  9. NKD2 methylation is associated with cell differentiation, TNM stage and distant metastasis significantly (all P < 0.05), and the overall survival time is longer in NKD2 unmethylated group compared to NKD2 methylated group (P < 0.05).

  10. NKD2 antagonizes Wnt signaling: myristoylated NKD2 interacts with Dvl-1 at the plasma membrane, and this interaction leads to their mutual ubiquitin-mediated proteasomal degradation.

  11. NKD2 represents a candidate target of 5p amplifications in soft tissue sarcomas and might play a crucial role during the progression of this disease.

  12. Naked2 acts as a cargo recognition and targeting (CaRT) protein to ensure proper delivery, tethering, and fusion of TGF-alpha-containing vesicles to a distinct region at the basolateral surface of polarized epithelial cells.

  13. identify an EGFR-independent action of TGF-alpha, in which it protects Naked2 from proteasomal degradation, thus ensuring its delivery to the basolateral surface of polarized epithelial cells

Naked Cuticle Homolog 2 (Drosophila) (NKD2) Antigen Profile

Protein Summary

This gene encodes a member of a family of proteins that function as negative regulators of Wnt receptor signaling through interaction with Dishevelled family members. The encoded protein participates in the delivery of transforming growth factor alpha-containing vesicles to the cell membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with NKD2

  • naked cuticle homolog 2b (nkd2b) antibody
  • naked cuticle 2 homolog (Drosophila) (Nkd2) antibody
  • naked cuticle homolog 2 (NKD2) antibody
  • naked cuticle homolog 2 (Nkd2) antibody
  • naked cuticle homolog 2a (nkd2a) antibody
  • 2210403L10Rik antibody
  • AW212591 antibody
  • Naked2 antibody
  • nkd2 antibody
  • nkd2l antibody

Protein level used designations for NKD2

naked cuticle homolog 2 , protein naked cuticle homolog 2-like , mNkd2 , naked cuticle 1 homolog , naked-2 , protein naked cuticle homolog 2 , Dvl-binding protein NKD2 , naked cuticle 2 homolog , naked 2a

GENE ID SPECIES
794221 Danio rerio
72293 Mus musculus
85409 Homo sapiens
308068 Rattus norvegicus
100049175 Danio rerio
Selected quality suppliers for anti-Naked Cuticle Homolog 2 (Drosophila) (NKD2) Antibodies
Did you look for something else?