Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) ELISA Kits

displays differential expression after induction by nerve growth factor [RGD, Feb 2006].. Additionally we are shipping NEDD8 Antibodies (144) and NEDD8 Proteins (28) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NEDD8 4738 Q15843
NEDD8 18002 P29595
NEDD8 25490 Q71UE8
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Top NEDD8 ELISA Kits at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 9.77 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
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Human
  96 Tests Log in to see 2 to 3 Days
$380.00
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Human
  96 Tests Log in to see 31 to 41 Days
$728.20
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Human
  1 kit Log in to see 5 to 8 Days
$923.19
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More ELISA Kits for NEDD8 Interaction Partners

Human Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. The cellular effects of NEDD8 inhibition can be manipulated based on the p53 (show TP53 ELISA Kits) status.

  2. Here we report that high expression of neddylation components, NEDD8 and NAE1, are associated with poor survival of Pancreatic ductal adenocarcinoma patients. Blockage of neddylation by MLN4924 significantly sensitizes pancreatic cancer cells to gemcitabine, reduced clonogenic survival, decreased invasion capacity, increased apoptosis and senescence

  3. Downregulation of NEDD8 enhanced the susceptibility of nasopharyngeal carcinoma cells to cisplatin and radiation.

  4. Furthermore, the authors characterized SENP8/DEN1 (show SENP8 ELISA Kits) as the protease that counteracts Ubc12 auto-neddylation, and observed aberrant neddylation of Ubc12 and other NEDD8 conjugation pathway components in SENP8 (show SENP8 ELISA Kits)-deficient cells.

  5. MKK7 (show MAP2K7 ELISA Kits) undergoes neddylation in human breast cancer cells

  6. complete blocking of CRLs at a higher inhibitor dose-induced cytotoxicity that was amplified by knockdown of CRL (show IL31RA ELISA Kits) regulator Cand1 (show CAND1 ELISA Kits).

  7. In conclusion, the authors revealed that E3 ligase HDM2 promotes NEDD8 NEDDylation of HBx to enhance HBx stability and chromatin localization, which in turn favors HBx-dependent transcriptional regulation, cell proliferation, and hepatitis B virus-driven tumor growth.

  8. CUL5 (show CUL5 ELISA Kits) neddylation may allosterically tune polyubiquitin (show UBB ELISA Kits) chain length and topology.

  9. This study identifies MyD88 (show MYD88 ELISA Kits) as a novel substrate of NEDD8, and demonstrate that MyD88 (show MYD88 ELISA Kits) NEDDylation antagonizes its ubiquitination.

  10. This study provides new knowledge of the CFTR (show CFTR ELISA Kits) biosynthetic pathway. It suggests that SYVN1 (show SYVN1 ELISA Kits) and FBXO2 (show FBXO2 ELISA Kits) represent two distinct multiprotein complexes that may degrade DeltaF508-CFTR (show CFTR ELISA Kits) in airway epithelia and identifies a new role for NEDD8 in regulating DeltaF508-CFTR (show CFTR ELISA Kits) ubiquitination.

Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. Downregulation of NEDD8 enhanced the susceptibility of nasopharyngeal carcinoma cells to cisplatin and radiation.

  2. Data show that NEDL2 regulates GDNF/Ret/Akt pathway depends on its Nedd8 ligase activity rather than ubiquitin ligase activity.

  3. neural precursor cell expressed developmentally downregulated protein 8 (Nedd8) modification of Cul-5 (show CUL5 ELISA Kits) is required for its interaction with TRAF6 (show TRAF6 ELISA Kits).

  4. Our findings provide mechanistic evidence of the effects of IAP (show ALPI ELISA Kits) antagonists in combination with NAE inhibitors, and demonstrate the potential of a new combination therapy for cancer.

  5. a role of Nedd8 in regulating caspase-1 (show CASP1 ELISA Kits) activation following inflammasome activation

  6. Nedd8 and its associated E2 carrier protein (Ubc12) and E3-SCF (show KITLG ELISA Kits) ligase play a key role in regulating the expression and activity of ENaC (show SCNN1A ELISA Kits) in alveolar pneumocytes.

  7. a new regulatory mechanism of RCAN1 (show RCAN1 ELISA Kits) function

  8. c-Cbl conjugates neural precursor cell-expressed, developmentally downregulated 8 (NEDD8), a ubiquitin-like protein, to TbetaRII at Lys556 and Lys567.

  9. The NEDD8 pathway appears to play an important role in CD4 (show CD4 ELISA Kits)+ T-cell-mediated inflammatory responses

  10. Nedd8 and AhR (show AHR ELISA Kits) localize to overlapping areas in the heart and spinal ganglia, raising the possibility that this interaction may play a role in organogenesis

Fruit Fly (Drosophila melanogaster) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. the Cul1 (show CUL1 ELISA Kits)-based SCF (show KITLG ELISA Kits) complex requires Nedd8 modification for the degradation processes of Ci, Arm, and CycE (show CCNE1 ELISA Kits) in vivo

  2. Genetic analyses indicate that a balance between neddylation and deneddylation maintained by DEN1 (show SENP8 ELISA Kits) is crucial for animal viability.

NEDD8 Antigen Profile

Antigen Summary

displays differential expression after induction by nerve growth factor

Gene names and symbols associated with NEDD8

  • neural precursor cell expressed, developmentally down-regulated 8 (NEDD8) antibody
  • neural precursor cell expressed, developmentally down-regulated gene 8 (Nedd8) antibody
  • neural precursor cell expressed, developmentally down-regulated 8 (Nedd8) antibody
  • CG10679 gene product from transcript CG10679-RB (Nedd8) antibody
  • neural precursor cell expressed, developmentally down-regulated 8 (nedd8) antibody
  • Nedd8 (Nedd8) antibody
  • ubiquitin-like protein Nedd8 (nedd8) antibody
  • neural precursor cell expressed, developmentally down-regulated 8 L homeolog (nedd8.L) antibody
  • CG10679 antibody
  • DDBDRAFT_0218116 antibody
  • DDBDRAFT_0238041 antibody
  • DDB_0218116 antibody
  • DDB_0238041 antibody
  • Dmel\\CG10679 antibody
  • dNEDD8 antibody
  • GB17785 antibody
  • NEDD-8 antibody
  • nedd8 antibody
  • nedd8.S antibody
  • Rub1 antibody
  • si:zc14a17.5 antibody
  • ubiquitin antibody

Protein level used designations for NEDD8

neddylin , ubiquitin-like protein Nedd8 , NEDD-8 , NEDD8 , neural precursor cell expressed developmentally down-regulated protein 8 , neural precursor cell expressed, developmentally down-regulated gene 8 , CG10679-PA , Nedd8-PA , neural precursor cell-expressed developmentally downregulated , neural precursor cell expressed, developmentally down-regulated 8 , Nedd8 , NEDD8 protein , neural precursor cell expressed, developmentally down-regulated 8 S homeolog

GENE ID SPECIES
4738 Homo sapiens
18002 Mus musculus
25490 Rattus norvegicus
35151 Drosophila melanogaster
286796 Bos taurus
368667 Danio rerio
480265 Canis lupus familiaris
549727 Xenopus (Silurana) tropicalis
552822 Apis mellifera
715763 Macaca mulatta
8621655 Dictyostelium discoideum AX4
100009008 Oryctolagus cuniculus
100301786 Oncorhynchus mykiss
100528101 Ictalurus punctatus
100520086 Sus scrofa
446966 Xenopus laevis
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