Neuritin 1 Proteins (NRN1)

NRN1 is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. Additionally we are shipping Neuritin 1 Antibodies (57) and Neuritin 1 Kits (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NRN1 51299 Q9NPD7
NRN1 68404 Q8CFV4
NRN1 83834 O08957
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Top Neuritin 1 Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Details
Escherichia coli (E. coli) Human Un-conjugated   50 μg 2 to 3 Days
$575.00
Details
Baculovirus infected Insect Cells Human His tag 50 μg 14 to 16 Days
$375.94
Details
Escherichia coli (E. coli) Human Un-conjugated Validation with Western Blot 20 μg 4 to 8 Days
$319.00
Details
Escherichia coli (E. coli) Human His tag   50 μg 4 Days
$313.50
Details
Escherichia coli (E. coli) Human His-SUMO Tag 100 μg 11 Days
$356.40
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Human Un-conjugated   0.005 mg 2 to 3 Days
$213.13
Details
Yeast Xenopus laevis His tag   1 mg 60 to 71 Days
$2,134.00
Details

NRN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)

Rat (Rattus) ,

More Proteins for Neuritin 1 (NRN1) Interaction Partners

Human Neuritin 1 (NRN1) interaction partners

  1. NRN1 is expressed more extensively in melanoma than in normal melanocytes and healthy tissue. Secreted NRN1 seems to play a role also in earlier phases of melanoma development as we can discover NRN1 over-expression to be associated to primary melanoma

  2. results suggest that DTNBP1 and NRN1 genes show a joint effect on the risk for schizophrenia spectrum disorders. Although the precise mechanism underlying this effect is unclear, the fact that these genes have been involved in synaptic maturation, connectivity and glutamate signalling suggests that our findings could be of value as a link to the schizophrenia aetiology.

  3. NRN1 is associated with depressive symptoms and executive function in a non-clinical sample. Our results also suggest that the role of NRN1 seems to be modulated by BDNF.

  4. On analysis of the expression of NRN1 in SMA patients for the first time, NRN1 could be a potential modifier gene

  5. Ca(2+)/calcineurin (CaN)/nuclear factor of activated T-cells (NFAT) c4 axis is required for neuritin-induced Kv4.2 transcriptional expression and potentiation of IA densities in cerebellum granule neurons.

  6. (i) NRN1 variability is a shared risk factor for both schizophrenia-spectrum disorders (SSD) and bipolar disorders (BPD), (ii) NRN1 may have a selective impact on age at onset and intelligence in SSD.

  7. Data indicate that neuritin not only plays an important role in the nervous system but also has an effect on the migration, senescence, proliferation, and viability of stem cells

  8. Neuritin is reduced in the brains of Alzheimer's disease (AD) patients.

  9. MiR-204 promotes apoptosis in oxidative stress-induced rat Schwann cells by suppressing neuritin expression

  10. we found neuritin is overexpressed in astrocytoma, which may be an important factor in tumorigenesis and progression of astrocytoma

  11. Data show that SMN and HuD form a complex in spinal motor axons, and that both interact with cpg15 mRNA in neurons.

  12. NRN1 polymorphisms have roles in fluid intelligence in schizophrenia

  13. By Northern blot, we confirm hypoxia-induced expression of insulin-like growth factor binding protein 3 (igfbp3), thioredoxin-interacting protein (txnip), neuritin (nrn1).

  14. CPG15 and CPG15-2 perform similar cellular functions but may play distinct roles in vivo through their cell-type- and tissue-specific transcriptional regulation

Mouse (Murine) Neuritin 1 (NRN1) interaction partners

  1. Following cerebral ischemia there is an increase in cpg15 expression in hippocampal astrocytes.

  2. Ca(2+)/calcineurin (CaN)/nuclear factor of activated T-cells (NFAT) c4 axis is required for neuritin-induced Kv4.2 transcriptional expression and potentiation of IA densities in cerebellum granule neurons.

  3. Neuritin prevents extremely low-frequency electromagnetic fields-exposure-induced memory deficit by increasing the hippocampal spine density.

  4. Neuritin can normalize neural deficits of Alzheimer's disease.

  5. Neuritin restors the reduction in dendritic spine density and the maturity of individual spines in primary hippocampal neuron cultures from a Alzheimer disease mouse model.

  6. Activity-dependent development of the visual system requires synapse stabilization and maturation via CPG15.

  7. CPG15 acts to stabilize active synapses on dendritic spines, resulting in selective spine and arbor stabilization and synaptic maturation, and that synapse stabilization mediated by CPG15 is critical for efficient learning

  8. Data show that SMN and HuD form a complex in spinal motor axons, and that both interact with cpg15 mRNA in neurons.

  9. Cpg15 is an immediate-early gene induced by Ca(2+) influx through NMDA receptors and L-type voltage-sensitive calcium channels. It requires convergent activation of the CaM kinase and MAP kinase pathways.

  10. Regulation of cpg15 expression during single whisker experience in the barrel cortex of adult mice.

  11. Data show that neuritin expression is well correlated to the maturation of hepatocytes and can be a useful tool to define the differentiation stage of hepatocytes.

  12. CPG15 may function as a new factor required in re-establishment of neuronal network after the injury.

  13. CPG15 and CPG15-2 perform similar cellular functions but may play distinct roles in vivo through their cell-type- and tissue-specific transcriptional regulation

Neuritin 1 (NRN1) Protein Profile

Protein Summary

This gene is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. In vitro assays demonstrated that this protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis.

Gene names and symbols associated with Neuritin 1 Proteins (NRN1)

  • neuritin 1 (NRN1)
  • neuritin 1a (nrn1a)
  • neuritin 1 (nrn1)
  • neuritin 1 (Nrn1)
  • 0710008J23Rik protein
  • Cpg15 protein
  • dJ380B8.2 protein
  • neuritin protein
  • Nrn protein
  • NRN1 protein
  • zgc:92828 protein

Protein level used designations for Neuritin 1 Proteins (NRN1)

neuritin , cpg15 , neuritin 1 , Neuritin , candidate plasticity gene 15 protein , candidate plasticity-related gene 15 , neuritin-1

GENE ID SPECIES
420873 Gallus gallus
436780 Danio rerio
462412 Pan troglodytes
100145075 Xenopus (Silurana) tropicalis
100306830 Salmo salar
51299 Homo sapiens
68404 Mus musculus
612757 Canis lupus familiaris
100155948 Sus scrofa
538730 Bos taurus
83834 Rattus norvegicus
100719410 Cavia porcellus
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