NRN1 Protein (His tag)
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- Target See all NRN1 Proteins
- NRN1 (Neuritin 1 (NRN1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This NRN1 protein is labelled with His tag.
- Purpose
- Recombinant Human Neuritin/NRN1 Protein (Baculovirus, His Tag)
- Sequence
- Met 1-Asn 115
- Characteristics
- A DNA sequence encoding the mature form of human NRN1 (Q9NPD7) (Met 1-Asn 115) was fused with a polyhistidine tag at the C-terminus.
- Purity
- > 85 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product NRN1 Protein
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Neuritin 1 (NRN1) (AA 28-116) protein (His tag)
NRN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Neuritin 1 (NRN1) (AA 28-116) protein (His-IF2DI Tag)NRN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Neuritin 1 (NRN1) (AA 1-142) protein (GST tag)NRN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neuritin 1 (NRN1) (AA 28-116) protein (His tag)Crystallography grade NRN1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Neuritin 1 (NRN1) (AA 28-116) protein (His tag)Crystallography grade NRN1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Neuritin 1 (NRN1) (AA 28-116) protein (His-SUMO Tag)NRN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- NRN1 (Neuritin 1 (NRN1))
- Alternative Name
- Neuritin/NRN1 (NRN1 Products)
- Synonyms
- NRN Protein, dJ380B8.2 Protein, 0710008J23Rik Protein, Cpg15 Protein, Nrn Protein, neuritin Protein, nrn1 Protein, zgc:92828 Protein, NRN1 Protein, cpg15 Protein, nrn Protein, nrn1-a Protein, nrn1-b Protein, nrn1b Protein, neuritin 1 Protein, neuritin 1a Protein, neuritin 1 S homeolog Protein, neuritin 1 L homeolog Protein, NRN1 Protein, Nrn1 Protein, nrn1a Protein, nrn1 Protein, nrn1.S Protein, nrn1.L Protein
- Background
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Background: Neuritin 1 (NRN1) is a member of neuritin family. Neuritin is a glycosylphosphatidylinositol- anchored protein induced by neural activity. It is expressed in postmitotic-differentiating neurons of the developing nervous system and a population of small-diameter neurons in the dorsal root ganglia and was anterogradely and retrogradely transported. Neuritin message is induced by neuronal activity and by the activity-regulated neurotrophins BDNF, nerve growth factor (NGF) and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic hippocampal and cortical cultures. Thus, neuritin is considered as a downstream effector of activity-induced neurite outgrowth. In clinical, neuritin levels in diabetes were reduced in both dorsal root ganglia and sciatic nerve of rats, and these deficits were reversed in vivo by treatment with NGF. This manipulation of neuritin levels in diabetes may provide a potential target for the therapeutic intervention in the management of neuropathy.
Synonym: dJ380B8.2,MGC44811,NRN
- UniProt
- Q9NPD7
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