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Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. Additionally we are shipping NTSR1 Kits (12) and NTSR1 Proteins (6) and many more products for this protein.
Showing 10 out of 90 products:
Human Monoclonal NTSR1 Primary Antibody for - ABIN1384022
Ovigne, Vermot-Desroches, Lecron, Portier, Lupker, Pecceu, Wijdenes: An antagonistic monoclonal antibody (B-N6) specific for the human neurotensin receptor-1. in Neuropeptides 1999
Human Polyclonal NTSR1 Primary Antibody for IHC (p) - ABIN271365
Gui, Liu, Yan, Gao: Neurotensin receptor 1 overexpression in inflammatory bowel diseases and colitis-associated neoplasia. in World journal of gastroenterology 2013
Cow (Bovine) Polyclonal NTSR1 Primary Antibody for WB - ABIN2777123
Carraway, Hassan: Neurotensin receptor binding and neurotensin-induced growth signaling in prostate cancer PC3 cells are sensitive to metabolic stress. in Regulatory peptides 2007
Show all 2 Pubmed References
The weight loss behaviors are mediated by distinct signaling pathways: Nts (show NTS Antibodies) action via NtsR1 is essential for the anorectic effect of the lateral hypothalamic Nts (show NTS Antibodies) circuit, but not for regulation of locomotor or drinking behavior.
Data demonstrate that the NTR1 can modulate the methamphetamine-induced striatal neuronal apoptosis independent of body temperature regulation. Possible mechanisms of NTR1 modulating methamphetamine-induced apoptosis include the regulation of dopamine and glutamate (show GRIN1 Antibodies) neurotransmission in the striatum.
The roles of neurotensin and its receptor NTR-1 on sperm capacitation and acrosome reaction in mice are reported.
sleep traits and a relationship between Ntsr1 and anxiety and despair behaviors in knockout mice
Data show that NTS1 (show NTS Antibodies)(-/-) mouse is an animal model of schizophrenia, particularly for the dysfunction of the prefrontal cortex.
Ntsr1 knockout mice showed a higher freezing rate than wild type mice at both first and second exposures under the condition where a relatively weak unconditioned stimulus (footshock)
Ntsr1 receptor subtype is necessary for normal dopaminergic function.
These findings support the role for Ntsr1 in the mediation of the metabolic effect of xenin (show COPA Antibodies) as well as neurotensin (show NTS Antibodies).
Neurotensin (show NTS Antibodies) type 1 receptor does not play a role in NT-induced analgesia, but that it is clearly implicated in thermal and feeding regulation, weight control, and NT-induced hypolocomotion.
constant activation of NT1 receptor generates an oncogenic regulation
NTSR1 knockdown impaired glioblastoma invasion and tumor growth through miR (show MLXIP Antibodies)-494 and identified a novel mechanism by which siNTSR1 suppressed glioblastoma invasion through the miR (show MLXIP Antibodies)-494/SOCS6 (show SOCS6 Antibodies) axis in glioblastoma.
This study strongly suggests that the addition of NTSR1 inhibitor in combination with platinum salt-based therapy will improve the response to the drug.
Our findings identify promoter methylation as an important process regulating the differential expression or silencing of NTSR1/2 in Colorectal cancer (CRC (show CALR Antibodies)) cells. Moreover, inhibition of NTSR1 repressed tumorigenic effects in CRC (show CALR Antibodies) cells, suggesting that NTSR1 may be used as a therapeutic target for CRC (show CALR Antibodies).
inducing exogenous neurotensin stimulation and enhancing NTR1 expression promoted tumor invasion rather than proliferation by accelerating epithelial-to-mesenchymal transition in hepatocellular carcinoma cells.
High NTR1 expression is associated with pancreatic ductal adenocarcinoma.
Data suggest that small molecule ligand binding to neurotensin receptor 1 (NTSR1) could facilitate the structure-based design of non-peptide ligands for the evaluation of the pharmacological potential of NTSR1 in neurological disorders and cancer.
The results reveal a positive feedback loop between NTS (show NTS Antibodies)/NTSR1 and Wnt (show WNT2 Antibodies)/beta-Catenin (show CTNNB1 Antibodies) signaling in glioblastoma cells that might be important for tumor development and provide potential therapeutic targets for glioblastoma.
NTSR1 overexpression is a poor prognostic factor in endometrial cancer, highlighting the contribution of NTS (show NTS Antibodies) in endometrial cancer progression
Heterodimerization of the kappa opioid receptor (show OPRK1 Antibodies) and neurotensin receptor 1 contributes to a novel beta-arrestin-2 (show ARRB2 Antibodies)-signaling pathway.
Silencing of miR-133alpha or overexpression of aftiphilin attenuated NTR1 trafficking to plasma membrane in human colonocytes.
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.
neurotensin receptor type 1
, neurotensin receptor 1 (high affinity)
, neurotensin receptor type 1-like
, high-affinity levocabastine-insensitive neurotensin receptor