NTSR1 antibody (N-Term)

Catalog No. ABIN2777123

There is 1 publication for this product available. The Rabbit Polyclonal anti-NTSR1 antibody is suitable to detect NTSR1 in samples from Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for NTSR1 antibody (N-Term) (ABIN2777123)

Target: NTSR1 (Neurotensin Receptor 1 (High Affinity) (NTSR1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NTSR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NTSR1 Antibody

Binding Specificity: N-Term

Purpose: NTSR1 Antibody - N-terminal region

Sequence: FGNASGNASE RVLAAPSSEL DVNTDIYSKV LVTAVYLALF VVGTVGNTVT

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 86%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against NTSR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NTSR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42048-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-NTSR1 antibody (ABIN2777123)

Carraway, Hassan: "Neurotensin receptor binding and neurotensin-induced growth signaling in prostate cancer PC3 cells are sensitive to metabolic stress." in: Regulatory peptides, Vol. 141, Issue 1-3, pp. 140-53, (2007) (PubMed).

Target Details for NTSR1

Target: NTSR1 (Neurotensin Receptor 1 (High Affinity) (NTSR1))

Alternative Name: NTSR1

Background:

Background Information: Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secre

Gene Name: Neurotensin receptor 1 (high affinity)

Alternative Symbols: NTR

Protein Name: Neurotensin receptor type 1

Molecular Weight: 46kDa

Gene ID: 4923

NCBI Accession: NP_002522

UniProt: P30989