anti-Nicotinamide phosphoribosyltransferase (NAMPT) Antibodies

NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. Additionally we are shipping NAMPT Kits (125) and NAMPT Proteins (54) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NAMPT 10135 P43490
NAMPT 59027 Q99KQ4
NAMPT 297508 Q80Z29
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Top anti-NAMPT Antibodies at antibodies-online.com

Showing 10 out of 364 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Detection of Human PBEF by Western Blot. Samples: Whole cell lysate (20 mcg/lane) from human pulmonary artery endothelial cells. Antibody: Affinity purified rabbit anti-PBEF antibody ABIN152026 used at 0.2 mcg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds. Western Blot: PBEF/Visfatin/NAMPT Antibody [ABIN152026] - Whole cell lysate from 293T, HeLa, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. 100 μL Log in to see 7 to 9 Days
$585.06
Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-PBEF1 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated ICC, FACS, IP, IHC, ELISA, WB Immunofluorescent confocal imaging of HEK293 cells using anti-Nampt (Visfatin-PBEF), mAb (OMNI379) . Nampt (Visfatin/PBEF) (green staining) is localized in the cytoplasm and nucleus (400x magnification). Nuclei are stained with Hoechst (blue staining). Immunohistochemical staining of Nampt using anti-Nampt (OMNI379)  in human kidney tissue (1:500 dilution). Immunoperoxidase staining of formalin-fixed and paraffin-embedded (FFPE) human kidney showing cytoplasmic staining (200x, brown color). 100 μg Log in to see 5 to 8 Days
$419.75
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PBEF1 Antibody Titration: </b>2.5ug/ml<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-PBEF1 <br /> Antibody Titration: 2.5 µg/mL <br /> Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of NAMPT Antibody (Center) (ABIN652958) in A375 cell line lysates (35 µg/lane). NAMPT (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skeletal muscle reacted with NAMPT Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB L1 rat brain, L2 rat liver lysates probed (ABIN727100) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band and observed band size: 54kDa. L1 rat brain, L2 rat liver lysates probed  at 1:200 in 4˚C. Followed by conjugation to secondary antibody -HRP) at 1:3000 90min in 37˚C. Predicted band and observed band size: 54kDa. 100 μL Log in to see 3 to 7 Days
$306.90
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Porcine Heart lysate; Primary Ab: 1µg/ml Rabbit Anti-Human VF Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 13 to 16 Days
$316.00
Details
Human Rabbit Un-conjugated IP 100 μL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB   100 μg Log in to see 4 to 6 Days
$280.00
Details

NAMPT Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-NAMPT Antibodies

  1. Dog (Canine) Polyclonal NAMPT Primary Antibody for ICC, IF - ABIN152026 : Ye, Simon, Maloney, Zambelli-Weiner, Gao, Grant, Easley, McVerry, Tuder, Standiford, Brower, Barnes, Garcia: Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. in American journal of respiratory and critical care medicine 2005 (PubMed)
    Show all 10 Pubmed References

  2. Human Monoclonal NAMPT Primary Antibody for ICC, FACS - ABIN1169028 : Bae, Kim, Kim, Kim, Koo, Jang, Yun, Yoo, Bae: Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1. in FEBS letters 2006 (PubMed)
    Show all 7 Pubmed References

  3. Human Polyclonal NAMPT Primary Antibody for IHC, ELISA - ABIN1169025 : Nowell, Richards, Fielding, Ognjanovic, Topley, Williams, Bryant-Greenwood, Jones: Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis. in Arthritis and rheumatism 2006 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal NAMPT Primary Antibody for IP - ABIN250753 : Krzysik-Walker, Ocón-Grove, Maddineni, Hendricks, Ramachandran: Is visfatin an adipokine or myokine? Evidence for greater visfatin expression in skeletal muscle than visceral fat in chickens. in Endocrinology 2008 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal NAMPT Primary Antibody for ELISA, WB - ABIN967254 : Jin, Zhuo, Guo, Field: p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal NAMPT Primary Antibody for IHC (p), WB - ABIN652958 : Samal, Sun, Stearns, Xie, Suggs, McNiece: Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. in Molecular and cellular biology 1994 (PubMed)
    Show all 3 Pubmed References

  7. Human Monoclonal NAMPT Primary Antibody for ELISA, WB - ABIN969344 : Rongvaux, Shea, Mulks, Gigot, Urbain, Leo, Andris: Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis. in European journal of immunology 2003 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal NAMPT Primary Antibody for WB - ABIN223662 : Gesing, Masternak, Wang, Joseph, Leeuwenburgh, Westbrook, Lewinski, Karbownik-Lewinska, Bartke: Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions. in The journals of gerontology. Series A, Biological sciences and medical sciences 2011 (PubMed)

  9. Cow (Bovine) Polyclonal NAMPT Primary Antibody for IHC, WB - ABIN2775322 : Chen, Chung, Chang, Tsai, Huang, Shin, Lee: Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. in The Journal of clinical endocrinology and metabolism 2006 (PubMed)
    Show all 2 Pubmed References

More Antibodies against NAMPT Interaction Partners

Human Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. hsa_circ_0005105 can promote extracellular matrix (ECM (show MMRN1 Antibodies)) degradation by regulating the expression of miR (show MLXIP Antibodies)-26a target NAMPT.

  2. Careful characterization of the kinetics of NAMPT inhibition in vivo allowed us to optimize dosing to produce sufficient NAD(+) depletion over time that resulted in efficacy in an HCT116 xenograft model. Our data demonstrate that direct phosphoribosylation of competitive inhibitors by the NAMPT enzyme is not required for potent in vitro cellular activity or in vivo antitumor efficacy.

  3. Results suggested that visfatin -1535C>T polymorphisms might be associated with decreased risk of HBV-HCC (show FAM126A Antibodies) among the ethnic Zhuang population in Guangxi, China.

  4. the present study elucidated the pathophysiological role of visfatin in breast cancer and revealed a proliferative and protective role for visfatin

  5. In this cohort of resistant hypertension patients diagnosed with ambulatory blood pressure measurements, the investigators found an independent correlation between higher visfatin levels and the presence of resistant hypertension and left ventricular hypertrophy.

  6. A potential oncogenic role of Nampt in Waldenstrom macroglobulinemia cells.

  7. factor with strong correlation with high visfatin values (p=0.001). High Visfatin levels seem to be strongly correlated with the presence and severity of peripheral arterial occlusive disease.

  8. These results suggested that the plasma visfatin level is associated with the presence of hepatocellular carcinoma (HCC (show FAM126A Antibodies)), and that a higher plasma visfatin level may be important in the pathogenesis of HCC (show FAM126A Antibodies).

  9. Increased expression of visfatin are associated with a more aggressive phenotype of colorectal carcinoma patients. It can trigger the epithelial mesenchymal transformation of CRC (show CALR Antibodies) cells via Akt (show AKT1 Antibodies)/GSK-3beta/beta-catenin (show CTNNB1 Antibodies) signals.

  10. Results showed that rs34861192 of RETN (show RETN Antibodies) and rs13237989 of NAMPT synergistically affected the levels of insulin (show INS Antibodies) and glycemic index.

Mouse (Murine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. observations demonstrate that NAMPT knockdown exerted antiatherogenic effects by promoting cholesterol efflux and macrophage RCT (show FOXE3 Antibodies) through the PPARalpha (show PPARA Antibodies)- LXRalpha (show NR1H3 Antibodies)- ABCA1 (show ABCA1 Antibodies)/G1pathway in vitro and in vivo

  2. Study found that primary mouse embryonic fibroblast (MEF) cells undergo progressive decline of NAMPT and NAD(+) contents during serial passaging before becoming senescent; further found that constitutive Nampt over-expression increases SIRT1 (show SIRT1 Antibodies) activity, increases the expression of antioxidant genes, superoxide dismutase 2 (show SOD2 Antibodies) and catalase (show CAT Antibodies) and promotes resistance against oxidative stress.

  3. NAMPT-mediated NAD(+) biosynthesis in adipocytes regulates adipose tissue function and multi-organ insulin (show INS Antibodies) sensitivity in mice.

  4. NAMPT-mediated NAD(+) biosynthesis is essential for vision in mice.

  5. NAMPT is involved in key basic cellular functions.

  6. role of Nampt in regulating osteoblast differentiation in primary mouse bone marrow-derived mesenchymal stem cells (BM-MSCs); Nampt expression was progressively elevated during BM-MSCs osteogenic differentiation

  7. The results suggest that NCOA6 (show NCOA6 Antibodies) stimulates insulin (show INS Antibodies) secretion, at least partially, by modulating Nampt expression in pancreatic beta-cells.

  8. the protein expression levels of TIMP-2 (show TIMP2 Antibodies) and PBEF in cloned placentae, were examined.

  9. NAMPT inhibited endothelial progenitor cell senescence through an SIRT1 (show SIRT1 Antibodies) AS lncRNA/miR (show MLXIP Antibodies)-22/SIRT1 (show SIRT1 Antibodies) pathway

  10. Visfatin upregulated CD36 (show CD36 Antibodies) and SRA (show MSR1 Antibodies) expression and downregulated ABCA1 (show ABCA1 Antibodies) and ABCG1 (show ABCG1 Antibodies) expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 Antibodies)-dependent pathways.

Pig (Porcine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. In a wild boar x Meishan F2 family nicotinamide phosphoribosyltransferase nicotinamide phosphoribosyltransferase SNP 669T>C was associated with muscling, fat deposition, growth and fattening, meat quality and other traits.

  2. cloning and characterization of porcine visfatin and its three alternate splicing variants is reported; sequence analysis indicated that variant 1 is the predominant form among species.

  3. The porcine visfatin gene cannot be considered as a marker of fat accumulation since the highest visfatin expression levels were associated with the leaner (show CACNA1A Antibodies) animals.

Cow (Bovine) Nicotinamide phosphoribosyltransferase (NAMPT) interaction partners

  1. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2 (show PTGS2 Antibodies), and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2 (show DAB2 Antibodies), and NR3C1 (show NR3C1 Antibodies). TNF (show TNF Antibodies) and IL6 (show IL6 Antibodies) levels were also decreased while those of NAMPT were unaffected.

  2. the presence of 35bp-insertion in visfatin gene may influence the birth weight and bodyweight in 6-month-old cows.

  3. These results indicate that mammary epithelial cells express the visfatin protein and secrete them into the milk.

NAMPT Antigen Profile

Protein Summary

This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.

Gene names and symbols associated with NAMPT

  • nicotinamide phosphoribosyltransferase (NAMPT) antibody
  • nicotinamide phosphoribosyltransferase (Nampt) antibody
  • nicotinamide phosphoribosyltransferase (nampt) antibody
  • Nicotinamide phosphoribosyltransferase (Smon_0680) antibody
  • Nicotinamide phosphoribosyltransferase (Mrub_2845) antibody
  • nicotinamide phosphoribosyltransferase (Cseg_3704) antibody
  • Nicotinamide phosphoribosyltransferase (BC1002_3997) antibody
  • nicotinamide phosphoribosyltransferase (Ftrac_2686) antibody
  • nicotinamide phosphoribosyltransferase (Varpa_5681) antibody
  • nicotinamide phosphoribosyltransferase (Celal_3900) antibody
  • Nicotinamide phosphoribosyltransferase (Deima_0880) antibody
  • Nicotinamide phosphoribosyltransferase (BC1001_3724) antibody
  • Nicotinamide phosphoribosyltransferase (Celly_1696) antibody
  • Nicotinamide phosphoribosyltransferase (Clole_1542) antibody
  • nicotinamide phosphoribosyltransferase (Tsp_05934) antibody
  • nicotinamide phosphoribosyltransferase S homeolog (nampt.S) antibody
  • 1110035O14Rik antibody
  • AI314458 antibody
  • AI480535 antibody
  • NAmPRTase antibody
  • pbef antibody
  • pbef1 antibody
  • VF antibody
  • visfatin antibody

Protein level used designations for NAMPT

NAmPRTase , pre-B cell-enhancing factor , pre-B-cell colony enhancing factor 1 , pre-B-cell colony-enhancing factor 1 , pre-B-cell colony-enhancing factor 1 homolog , visfatin , PBEF , Nicotinamide phosphoribosyltransferase , nicotinamide phosphoribosyltransferase , pre-B-cell colony-enhancing factor-like protein

GENE ID SPECIES
10135 Homo sapiens
59027 Mus musculus
417707 Gallus gallus
100223583 Taeniopygia guttata
595123 Sus scrofa
463648 Pan troglodytes
520472 Bos taurus
297508 Rattus norvegicus
496856 Xenopus (Silurana) tropicalis
8600403 Streptobacillus moniliformis DSM 12112
8880961 Meiothermus ruber DSM 1279
9105230 Caulobacter segnis ATCC 21756
9113310 Burkholderia sp. CCGE1002
10012838 Marivirga tractuosa DSM 4126
10132554 Variovorax paradoxus EPS
10146329 Cellulophaga algicola DSM 14237
10150218 Deinococcus maricopensis DSM 21211
10225315 Burkholderia sp. CCGE1001
10263712 Cellulophaga lytica DSM 7489
10331257 Clostridium lentocellum DSM 5427
10911088 Trichinella spiralis
398502 Xenopus laevis
100059684 Equus caballus
100856598 Canis lupus familiaris
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