NAMPT antibody (AA 400-426)

Catalog No. ABIN3031997

The Rabbit Polyclonal anti-NAMPT antibody is suitable to detect NAMPT in samples from Human. It has been validated for WB, IHC and ELISA.

Quick Overview for NAMPT antibody (AA 400-426) (ABIN3031997)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAMPT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-NAMPT Antibody

Binding Specificity: AA 400-426

Purpose: NAMPT Antibody

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Pig

Purification: Antigen affinity

Immunogen: A portion of amino acids 400-426 from the human protein was used as the immunogen for this NAMPT antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NAMPT antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NAMPT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Alternative Name: NAMPT

Background: NAMPT catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

UniProt: P43490